PDB: 1mdw Compound: calpain ii, catalytic subunit Classification: HYDROLASE Entry date in PDB: 2003-04-29 Resolution [Å]: 1.95 R-Factor: 0.207

CHAIN: A SWISS-PROT/TREMBL: Q07009    KEYWORD: 3D-structure    Calcium-binding    Hydrolase    Multigene family    Repeat    Thiol protease    EC: 3.4.22.53 SCOP: d.3.1.3 Alpha and beta proteins (a+b)    Cysteine proteinases    Cysteine proteinases    Calpain large subunit, catalytic domain (domain II)    Calpain large subunit, catalytic domain (domain II)    Rat (Rattus norvegicus), M-type GO:  intracellular    calcium ion binding    calpain activity    cysteine-type endopeptidase activity    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: Q07009    KEYWORD: 3D-structure    Calcium-binding    Hydrolase    Multigene family    Repeat    Thiol protease    EC: 3.4.22.53 SCOP: d.3.1.3 Alpha and beta proteins (a+b)    Cysteine proteinases    Cysteine proteinases    Calpain large subunit, catalytic domain (domain II)    Calpain large subunit, catalytic domain (domain II)    Rat (Rattus norvegicus), M-type GO:  intracellular    calcium ion binding    calpain activity    cysteine-type endopeptidase activity    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB40 clusters

1mdw_A_224 - HE => SUBCLASS : 1.1.1
1mdw_A_328 - HE => SUBCLASS : 2.3.1
1mdw_A_328 - HE => SUBCLASS : 2.3.8
1mdw_A_328 - HE => SUBCLASS : 2.5.1
1mdw_A_138 - HA => SUBCLASS : 2.1.1
1mdw_A_264 - HA => SUBCLASS : 2.1.5
1mdw_A_74 - EH => SUBCLASS : 1.1.1
1mdw_A_74 - EH => SUBCLASS : 1.1.18
1mdw_A_211 - EH => SUBCLASS : 6.8.2
1mdw_A_148 - AR => SUBCLASS : 1.1.1
1mdw_A_148 - AR => SUBCLASS : 1.1.5
1mdw_A_105 - HH => SUBCLASS : 1.1.6

Loops in ArchDB95 clusters

1mdw_A_74 - EH => SUBCLASS : 1.1.1
1mdw_A_211 - EH => SUBCLASS : 6.23.2
1mdw_A_148 - AR => SUBCLASS : 2.4.2
1mdw_A_105 - HH => SUBCLASS : 1.1.7
1mdw_A_224 - HE => SUBCLASS : 1.1.1
1mdw_A_328 - HE => SUBCLASS : 2.2.1
1mdw_A_328 - HE => SUBCLASS : 2.3.8
1mdw_A_138 - HA => SUBCLASS : 2.1.1
1mdw_A_264 - HA => SUBCLASS : 2.1.3
1mdw_A_138 - HA => SUBCLASS : 2.1.3

Loops in ArchDB-EC clusters

1mdw_A_105 - HH => SUBCLASS : 1.1.9

Loops not clustered in ArchDB

1mdw_A_148 - AR
1mdw_A_25 - EH
1mdw_A_164 - EH
1mdw_A_277 - EH
1mdw_A_323 - EH
1mdw_A_237 - HA
1mdw_A_138 - HA
1mdw_A_158 - HA
1mdw_A_237 - HA
1mdw_A_158 - HA
1mdw_A_264 - HA
1mdw_A_309 - HE
1mdw_A_177 - HE
1mdw_A_118 - HE
1mdw_A_55 - HE
1mdw_A_78 - HH
1mdw_A_32 - HH

1df0 A - percentage of sequence identity: 100
1kfu L - percentage of sequence identity: 93
1kfx L - percentage of sequence identity: 93
1kxr A - percentage of sequence identity: 70
1kxr B - percentage of sequence identity: 70
1mdw A - percentage of sequence identity: 100
1mdw B - percentage of sequence identity: 100
1qxp A - percentage of sequence identity: 73
1qxp B - percentage of sequence identity: 73
1tl9 A - percentage of sequence identity: 70
1tlo A - percentage of sequence identity: 70
1u5i A - percentage of sequence identity: 100
1zcm A - percentage of sequence identity: 70
2ary A - percentage of sequence identity: 71
2ary B - percentage of sequence identity: 71