PDB: 1mld Compound: Malate dehydrogenase Classification: OXIDOREDUCTASE(NAD(A)-CHOH(D)) Entry date in PDB: 1995-01-26 Resolution [Å]: 1.90 R-Factor: 0.211

CHAIN: A SWISS-PROT/TREMBL: P00346    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    Tricarboxylic acid cycle    EC: 1.1.1.37 SCOP: c.2.1.5 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    LDH N-terminal domain-like    Malate dehydrogenase    Pig (Sus scrofa) SCOP: d.162.1.1 Alpha and beta proteins (a+b)    LDH C-terminal domain-like    LDH C-terminal domain-like    Lactate & malate dehydrogenases, C-terminal domain    Malate dehydrogenase    Pig (Sus scrofa) GO:  L-lactate dehydrogenase activity    L-malate dehydrogenase activity    malate dehydrogenase activity    oxidoreductase activity    glycolysis    malate metabolism    tricarboxylic acid cycle intermediate metabolism    CHAIN: B SWISS-PROT/TREMBL: P00346    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    Tricarboxylic acid cycle    EC: 1.1.1.37 SCOP: c.2.1.5 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    LDH N-terminal domain-like    Malate dehydrogenase    Pig (Sus scrofa) SCOP: d.162.1.1 Alpha and beta proteins (a+b)    LDH C-terminal domain-like    LDH C-terminal domain-like    Lactate & malate dehydrogenases, C-terminal domain    Malate dehydrogenase    Pig (Sus scrofa) GO:  L-lactate dehydrogenase activity    L-malate dehydrogenase activity    malate dehydrogenase activity    oxidoreductase activity    glycolysis    malate metabolism    tricarboxylic acid cycle intermediate metabolism    CHAIN: C SWISS-PROT/TREMBL: P00346    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    Tricarboxylic acid cycle    EC: 1.1.1.37 SCOP: c.2.1.5 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    LDH N-terminal domain-like    Malate dehydrogenase    Pig (Sus scrofa) SCOP: d.162.1.1 Alpha and beta proteins (a+b)    LDH C-terminal domain-like    LDH C-terminal domain-like    Lactate & malate dehydrogenases, C-terminal domain    Malate dehydrogenase    Pig (Sus scrofa) GO:  L-lactate dehydrogenase activity    L-malate dehydrogenase activity    malate dehydrogenase activity    oxidoreductase activity    glycolysis    malate metabolism    tricarboxylic acid cycle intermediate metabolism    CHAIN: D SWISS-PROT/TREMBL: P00346    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    Tricarboxylic acid cycle    EC: 1.1.1.37 SCOP: c.2.1.5 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    LDH N-terminal domain-like    Malate dehydrogenase    Pig (Sus scrofa) SCOP: d.162.1.1 Alpha and beta proteins (a+b)    LDH C-terminal domain-like    LDH C-terminal domain-like    Lactate & malate dehydrogenases, C-terminal domain    Malate dehydrogenase    Pig (Sus scrofa) GO:  L-lactate dehydrogenase activity    L-malate dehydrogenase activity    malate dehydrogenase activity    oxidoreductase activity    glycolysis    malate metabolism    tricarboxylic acid cycle intermediate metabolism

Image Source: PDB

Loops in ArchDB95 clusters

1mld_A_112 - EH => SUBCLASS : 4.17.1
1mld_A_71 - EH => SUBCLASS : 11.3.1
1mld_A_90 - HE => SUBCLASS : 4.1.1
1mld_A_62 - HE => SUBCLASS : 4.12.1
1mld_A_13 - HE => SUBCLASS : 5.2.5
1mld_A_13 - HE => SUBCLASS : 5.34.1

Loops in ArchDB-EC clusters

1mld_A_13 - HE => SUBCLASS : 5.5.2

Loops not clustered in ArchDB

1mld_A_2 - EH
1mld_A_274 - EH
1mld_A_181 - EH
1mld_A_142 - EH
1mld_A_52 - EH
1mld_A_28 - EH
1mld_A_249 - HA
1mld_A_172 - HA
1mld_A_263 - HA
1mld_A_249 - HA
1mld_A_172 - HA
1mld_A_263 - HA
1mld_A_225 - HE
1mld_A_120 - HE
1mld_A_37 - HE
1mld_A_147 - HE
1mld_A_196 - HH

1mld A - percentage of sequence identity: 100
1mld B - percentage of sequence identity: 100
1mld C - percentage of sequence identity: 100
1mld D - percentage of sequence identity: 100