PDB: 1nfi Compound: nf-kappa-b p65 Classification: COMPLEX (TRANSCRIPTION REG/ANK REPEAT) Entry date in PDB: 1998-11-18 Resolution [Å]: 2.70 R-Factor: 0.223

CHAIN: A SWISS-PROT/TREMBL: P19838    KEYWORD: 3D-structure    Activator    Alternative splicing    ANK repeat    Apoptosis    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Transcription regulation    Ubl conjugation    SCOP: b.1.18.1 All beta proteins    Immunoglobulin-like beta-sandwich    E set domains    NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain    p65 subunit of NF-kappa B (NFKB), dimerization domain    Human (Homo sapiens) SCOP: b.2.5.3 All beta proteins    Common fold of diphtheria toxin/transcription factors/cytochrome f    p53-like transcription factors    Rel/Dorsal transcription factors, DNA-binding domain    p65 subunit of NF-kappa B (NFKB), N-terminal domain    Human (Homo sapiens) GO:  nucleus    transcription factor activity    regulation of transcription    regulation of transcription, DNA-dependent    CHAIN: B SWISS-PROT/TREMBL: P19838    KEYWORD: 3D-structure    Activator    ANK repeat    Apoptosis    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Transcription regulation    Ubl conjugation    SCOP: b.1.18.1 All beta proteins    Immunoglobulin-like beta-sandwich    E set domains    NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain    p50 subunit of NF-kappa B transcription factor    Human (Homo sapiens) GO:  nucleus    protein binding    transcription factor activity    regulation of transcription    regulation of transcription, DNA-dependent    signal transduction    CHAIN: C SWISS-PROT/TREMBL: P19838    KEYWORD: 3D-structure    Activator    Alternative splicing    ANK repeat    Apoptosis    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Transcription regulation    Ubl conjugation    SCOP: b.1.18.1 All beta proteins    Immunoglobulin-like beta-sandwich    E set domains    NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain    p65 subunit of NF-kappa B (NFKB), dimerization domain    Human (Homo sapiens) SCOP: b.2.5.3 All beta proteins    Common fold of diphtheria toxin/transcription factors/cytochrome f    p53-like transcription factors    Rel/Dorsal transcription factors, DNA-binding domain    p65 subunit of NF-kappa B (NFKB), N-terminal domain    Human (Homo sapiens) GO:  nucleus    transcription factor activity    regulation of transcription    regulation of transcription, DNA-dependent    CHAIN: D SWISS-PROT/TREMBL: P19838    KEYWORD: 3D-structure    Activator    ANK repeat    Apoptosis    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Transcription regulation    Ubl conjugation    SCOP: b.1.18.1 All beta proteins    Immunoglobulin-like beta-sandwich    E set domains    NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain    p50 subunit of NF-kappa B transcription factor    Human (Homo sapiens) GO:  nucleus    protein binding    transcription factor activity    regulation of transcription    regulation of transcription, DNA-dependent    signal transduction    CHAIN: E SWISS-PROT/TREMBL: P25963    KEYWORD: 3D-structure    ANK repeat    Phosphorylation    Repeat    Ubl conjugation    SCOP: d.211.1.1 Alpha and beta proteins (a+b)    beta-hairpin-alpha-hairpin repeat    Ankyrin repeat    Ankyrin repeat    I-kappa-B-alpha    Human (Homo sapiens) GO:   CHAIN: F SWISS-PROT/TREMBL: P25963    KEYWORD: 3D-structure    ANK repeat    Phosphorylation    Repeat    Ubl conjugation    SCOP: d.211.1.1 Alpha and beta proteins (a+b)    beta-hairpin-alpha-hairpin repeat    Ankyrin repeat    Ankyrin repeat    I-kappa-B-alpha    Human (Homo sapiens) GO:

Image Source: PDB

1a3q A - percentage of sequence identity: 64
1bfs - - percentage of sequence identity: 99
1ikn D - percentage of sequence identity: 100
1k3z B - percentage of sequence identity: 99
1my7 A - percentage of sequence identity: 99
1ooa A - percentage of sequence identity: 99