PDB: 1nvp Compound: tata box binding protein Classification: TRANSCRIPTION/DNA Entry date in PDB: 2003-10-21 Resolution [Å]: 2.10 R-Factor: 0.229

CHAIN: A SWISS-PROT/TREMBL: P20226    KEYWORD: 3D-structure    Disease mutation    DNA-binding    Nuclear protein    Polymorphism    Repeat    Transcription    Triplet repeat expansion    SCOP: d.129.1.1 Alpha and beta proteins (a+b)    TBP-like    TATA-box binding protein-like    TATA-box binding protein (TBP), C-terminal domain    TATA-box binding protein (TBP), C-terminal domain    Human (Homo sapiens) SCOP: d.129.1.1 Alpha and beta proteins (a+b)    TBP-like    TATA-box binding protein-like    TATA-box binding protein (TBP), C-terminal domain    TATA-box binding protein (TBP), C-terminal domain    Human (Homo sapiens) GO:  nucleus    transcription factor TFIID complex    binding    DNA binding    RNA polymerase II transcription factor activity    regulation of transcription, DNA-dependent    transcription initiation from RNA polymerase II promoter    CHAIN: B SWISS-PROT/TREMBL: P52655    KEYWORD: Alternative initiation    Nuclear protein    Transcription regulation    SCOP: a.32.1.1 All alpha proteins    Transcription factor IIA (TFIIA), alpha-helical domain    Transcription factor IIA (TFIIA), alpha-helical domain    Transcription factor IIA (TFIIA), alpha-helical domain    Large chain TOA1, N-terminal domain    Human (Homo sapiens) GO:  nucleus    transcription initiation factor activity    transcription initiation from RNA polymerase II promoter    CHAIN: C SWISS-PROT/TREMBL: P52655    KEYWORD: Alternative initiation    Nuclear protein    Transcription regulation    SCOP: b.56.1.1 All beta proteins    Transcription factor IIA (TFIIA), beta-barrel domain    Transcription factor IIA (TFIIA), beta-barrel domain    Transcription factor IIA (TFIIA), beta-barrel domain    Large chain TOA1, C-terminal domain    Human (Homo sapiens) GO:  nucleus    transcription initiation factor activity    transcription initiation from RNA polymerase II promoter    CHAIN: D SWISS-PROT/TREMBL: P52657    KEYWORD: Nuclear protein    Transcription regulation    SCOP: a.32.1.1 All alpha proteins    Transcription factor IIA (TFIIA), alpha-helical domain    Transcription factor IIA (TFIIA), alpha-helical domain    Transcription factor IIA (TFIIA), alpha-helical domain    Small chain TOA2, N-terminal domain    Human (Homo sapiens) SCOP: b.56.1.1 All beta proteins    Transcription factor IIA (TFIIA), beta-barrel domain    Transcription factor IIA (TFIIA), beta-barrel domain    Transcription factor IIA (TFIIA), beta-barrel domain    Small chain TOA2, C-terminal domain    Human (Homo sapiens) GO:  transcription factor TFIIA complex    RNA polymerase II transcription factor activity    transcription initiation from RNA polymerase II promoter

Image Source: PDB

Loops in ArchDB40 clusters

1nvp_D_57 - HA => SUBCLASS : 2.1.1
1nvp_B_10 - HH => SUBCLASS : 3.2.10
1nvp_B_10 - HH => SUBCLASS : 3.9.1
1nvp_D_10 - HH => SUBCLASS : 4.1.1
1nvp_D_10 - HH => SUBCLASS : 4.4.1

Loops in ArchDB95 clusters

1nvp_B_10 - HH => SUBCLASS : 3.2.6
1nvp_B_10 - HH => SUBCLASS : 3.4.3
1nvp_D_10 - HH => SUBCLASS : 4.1.1
1nvp_D_57 - HA => SUBCLASS : 2.1.4
1nvp_C_334 - HA => SUBCLASS : 2.3.4

Loops not clustered in ArchDB

1nvp_D_71 - HA
1nvp_C_348 - HA
1nvp_D_30 - HE

1cdw A - percentage of sequence identity: 99
1nh2 A - percentage of sequence identity: 81
1qna A - percentage of sequence identity: 83
null nu - percentage of sequence identity: 0