PDB: 1o6z Compound: malate dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 2003-02-06 Resolution [Å]: 1.95 R-Factor: 0.194

CHAIN: A SWISS-PROT/TREMBL: Q07841    KEYWORD: 3D-structure    NAD    Oxidoreductase    Tricarboxylic acid cycle    EC: 1.1.1.37 SCOP: c.2.1.5 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    LDH N-terminal domain-like    Malate dehydrogenase    Archaeon Haloarcula marismortui SCOP: d.162.1.1 Alpha and beta proteins (a+b)    LDH C-terminal domain-like    LDH C-terminal domain-like    Lactate & malate dehydrogenases, C-terminal domain    Malate dehydrogenase    Archaeon Haloarcula marismortui GO:  L-lactate dehydrogenase activity    oxidoreductase activity    glycolysis    tricarboxylic acid cycle intermediate metabolism    CHAIN: B SWISS-PROT/TREMBL: Q07841    KEYWORD: 3D-structure    NAD    Oxidoreductase    Tricarboxylic acid cycle    EC: 1.1.1.37 SCOP: c.2.1.5 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    LDH N-terminal domain-like    Malate dehydrogenase    Archaeon Haloarcula marismortui SCOP: d.162.1.1 Alpha and beta proteins (a+b)    LDH C-terminal domain-like    LDH C-terminal domain-like    Lactate & malate dehydrogenases, C-terminal domain    Malate dehydrogenase    Archaeon Haloarcula marismortui GO:  L-lactate dehydrogenase activity    oxidoreductase activity    glycolysis    tricarboxylic acid cycle intermediate metabolism    CHAIN: C SWISS-PROT/TREMBL: Q07841    KEYWORD: 3D-structure    NAD    Oxidoreductase    Tricarboxylic acid cycle    EC: 1.1.1.37 SCOP: c.2.1.5 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    LDH N-terminal domain-like    Malate dehydrogenase    Archaeon Haloarcula marismortui SCOP: d.162.1.1 Alpha and beta proteins (a+b)    LDH C-terminal domain-like    LDH C-terminal domain-like    Lactate & malate dehydrogenases, C-terminal domain    Malate dehydrogenase    Archaeon Haloarcula marismortui GO:  L-lactate dehydrogenase activity    oxidoreductase activity    glycolysis    tricarboxylic acid cycle intermediate metabolism    CHAIN: D SWISS-PROT/TREMBL: Q07841    KEYWORD: 3D-structure    NAD    Oxidoreductase    Tricarboxylic acid cycle    EC: 1.1.1.37 SCOP: c.2.1.5 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    LDH N-terminal domain-like    Malate dehydrogenase    Archaeon Haloarcula marismortui SCOP: d.162.1.1 Alpha and beta proteins (a+b)    LDH C-terminal domain-like    LDH C-terminal domain-like    Lactate & malate dehydrogenases, C-terminal domain    Malate dehydrogenase    Archaeon Haloarcula marismortui GO:  L-lactate dehydrogenase activity    oxidoreductase activity    glycolysis    tricarboxylic acid cycle intermediate metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1o6z_A_283 - HA => SUBCLASS : 2.2.15
1o6z_A_48 - EH => SUBCLASS : 1.1.10
1o6z_A_23 - EH => SUBCLASS : 4.14.1
1o6z_A_134 - EH => SUBCLASS : 4.28.1
1o6z_A_297 - EH => SUBCLASS : 6.12.1
1o6z_A_199 - AR => SUBCLASS : 5.2.1

Loops in ArchDB95 clusters

1o6z_A_48 - EH => SUBCLASS : 1.1.10
1o6z_A_23 - EH => SUBCLASS : 4.7.1
1o6z_A_134 - EH => SUBCLASS : 4.17.1
1o6z_A_297 - EH => SUBCLASS : 6.8.1
1o6z_A_199 - AR => SUBCLASS : 3.2.1
1o6z_A_77 - AR => SUBCLASS : 10.1.1
1o6z_A_31 - HE => SUBCLASS : 4.2.1
1o6z_A_165 - HE => SUBCLASS : 6.1.1
1o6z_A_109 - HE => SUBCLASS : 6.39.1
1o6z_A_283 - HA => SUBCLASS : 2.2.22
1o6z_A_191 - HA => SUBCLASS : 3.5.1

Loops in ArchDB-EC clusters

1o6z_A_165 - HE => SUBCLASS : 6.2.1

Loops not clustered in ArchDB

1o6z_A_187 - AR
1o6z_A_199 - AR
1o6z_A_187 - AR
1o6z_A_77 - AR
1o6z_A_93 - EH
1o6z_A_207 - EH
1o6z_A_160 - EH
1o6z_A_268 - HA
1o6z_A_191 - HA
1o6z_A_283 - HA
1o6z_A_268 - HA
1o6z_A_56 - HE
1o6z_A_142 - HE
1o6z_A_248 - HE
1o6z_A_222 - HH

1d3a A - percentage of sequence identity: 99
1d3a B - percentage of sequence identity: 99
1gt2 A - percentage of sequence identity: 100
1gt2 B - percentage of sequence identity: 100
1hlp A - percentage of sequence identity: 99
1hlp B - percentage of sequence identity: 99
1o6z A - percentage of sequence identity: 100
1o6z B - percentage of sequence identity: 100
1o6z C - percentage of sequence identity: 100
1o6z D - percentage of sequence identity: 100
2hlp A - percentage of sequence identity: 99
2hlp B - percentage of sequence identity: 99