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Information on 1ogs
PDB: 1ogs
Compound: glucosylceramidase
Classification: HYDROLASE
Entry date in PDB: 2003-07-03
Resolution [Å]: 2.00
R-Factor: 0.195


CHAIN: A
SWISS-PROT/TREMBL: P04062
   KEYWORD: Alternative initiation    Disease mutation    Gaucher disease    Glycoprotein    Glycosidase    Hydrolase    Lysosome    Membrane    Pharmaceutical    Polymorphism    Signal    Sphingolipid metabolism   
EC: 3.2.1.45
SCOP: b.71.1.2 All beta proteins    Glycosyl hydrolase domain    Glycosyl hydrolase domain    Composite domain of glycosyl hydrolase families 5, 30, 39 and 51    Glucosylceramidase    Human (Homo sapiens)
SCOP: b.71.1.2 All beta proteins    Glycosyl hydrolase domain    Glycosyl hydrolase domain    Composite domain of glycosyl hydrolase families 5, 30, 39 and 51    Glucosylceramidase    Human (Homo sapiens)
SCOP: c.1.8.3 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    (Trans)glycosidases    beta-glycanases    Glucosylceramidase, catalytic domain    Human (Homo sapiens)
GO:  lysosome    glucosylceramidase activity    lysosome organization and biogenesis    sphingolipid metabolism   


CHAIN: B
SWISS-PROT/TREMBL: P04062
   KEYWORD: Alternative initiation    Disease mutation    Gaucher disease    Glycoprotein    Glycosidase    Hydrolase    Lysosome    Membrane    Pharmaceutical    Polymorphism    Signal    Sphingolipid metabolism   
EC: 3.2.1.45
SCOP: b.71.1.2 All beta proteins    Glycosyl hydrolase domain    Glycosyl hydrolase domain    Composite domain of glycosyl hydrolase families 5, 30, 39 and 51    Glucosylceramidase    Human (Homo sapiens)
SCOP: b.71.1.2 All beta proteins    Glycosyl hydrolase domain    Glycosyl hydrolase domain    Composite domain of glycosyl hydrolase families 5, 30, 39 and 51    Glucosylceramidase    Human (Homo sapiens)
SCOP: c.1.8.3 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    (Trans)glycosidases    beta-glycanases    Glucosylceramidase, catalytic domain    Human (Homo sapiens)
GO:  lysosome    glucosylceramidase activity    lysosome organization and biogenesis    sphingolipid metabolism   
1ogs Image
Image Source: PDB

Stored Loops of 1ogs

Loops in ArchDB40 clusters

1ogs_A_444 - HA => SUBCLASS : 3.1.1
1ogs_A_468 - HA => SUBCLASS : 3.2.1
1ogs_A_402 - HA => SUBCLASS : 4.1.1
1ogs_A_410 - EH => SUBCLASS : 1.1.3
1ogs_A_80 - EH => SUBCLASS : 1.1.4
1ogs_A_478 - AR => SUBCLASS : 3.5.4
1ogs_A_456 - AR => SUBCLASS : 3.8.1
1ogs_A_290 - HH => SUBCLASS : 1.1.8
1ogs_A_290 - HH => SUBCLASS : 1.1.21
1ogs_A_87 - HH => SUBCLASS : 2.1.2
1ogs_A_87 - HH => SUBCLASS : 2.1.8

Loops in ArchDB95 clusters

1ogs_A_410 - EH => SUBCLASS : 1.1.4
1ogs_A_80 - EH => SUBCLASS : 2.2.1
1ogs_A_478 - AR => SUBCLASS : 3.6.7
1ogs_A_456 - AR => SUBCLASS : 5.1.1
1ogs_A_290 - HH => SUBCLASS : 1.1.39
1ogs_A_87 - HH => SUBCLASS : 2.1.29
1ogs_A_87 - HH => SUBCLASS : 2.3.2
1ogs_A_444 - HA => SUBCLASS : 3.1.1
1ogs_A_468 - HA => SUBCLASS : 3.3.1
1ogs_A_402 - HA => SUBCLASS : 4.1.1

Loops in ArchDB-EC clusters

1ogs_A_87 - HH => SUBCLASS : 2.1.6

Loops not clustered in ArchDB

1ogs_A_478 - AR
1ogs_A_50 - AR
1ogs_A_65 - AR
1ogs_A_375 - AR
1ogs_A_14 - AR
1ogs_A_50 - AR
1ogs_A_65 - AR
1ogs_A_375 - AR
1ogs_A_456 - AR
1ogs_A_14 - AR
1ogs_A_118 - EH
1ogs_A_335 - EH
1ogs_A_307 - EH
1ogs_A_277 - EH
1ogs_A_229 - EH
1ogs_A_173 - EH
1ogs_A_402 - HA
1ogs_A_432 - HA
1ogs_A_444 - HA
1ogs_A_36 - HA
1ogs_A_468 - HA
1ogs_A_6 - HA
1ogs_A_432 - HA
1ogs_A_36 - HA
1ogs_A_6 - HA
1ogs_A_98 - HE
1ogs_A_320 - HE
1ogs_A_357 - HE
1ogs_A_415 - HE
1ogs_A_299 - HE
1ogs_A_264 - HE
1ogs_A_204 - HE
1ogs_A_157 - HE
1ogs_A_151 - HH
1ogs_A_253 - HH

Homologous structures to 1ogs classified in ArchDB

1ogs A - percentage of sequence identity: 100
1ogs B - percentage of sequence identity: 100
1y7v A - percentage of sequence identity: 100
1y7v B - percentage of sequence identity: 100
2f61 A - percentage of sequence identity: 100
2f61 B - percentage of sequence identity: 100