PDB: 1olu Compound: 2-oxoisovalerate dehydrogenase alpha subunit Classification: OXIDOREDUCTASE Entry date in PDB: 2003-08-28 Resolution [Å]: 1.90 R-Factor: 0.161

CHAIN: A SWISS-PROT/TREMBL: P12694    KEYWORD: 3D-structure    Disease mutation    Flavoprotein    Maple syrup urine disease    Mitochondrion    Oxidoreductase    Phosphorylation    Thiamine pyrophosphate    Transit peptide    EC: 1.2.4.4 SCOP: c.36.1.11 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Branched-chain alpha-keto acid dehydrogenase PP module    Branched-chain alpha-keto acid dehydrogenase, PP module    Human (Homo sapiens) GO:  oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor    metabolism    CHAIN: B SWISS-PROT/TREMBL: P21953    KEYWORD: 3D-structure    Disease mutation    Maple syrup urine disease    Mitochondrion    Oxidoreductase    Transit peptide    EC: 1.2.4.4 SCOP: c.36.1.7 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    Branched-chain alpha-keto acid dehydrogenase Pyr module    Branched-chain alpha-keto acid dehydrogenase, Pyr module    Human (Homo sapiens) SCOP: c.48.1.2 Alpha and beta proteins (a/b)    TK C-terminal domain-like    TK C-terminal domain-like    Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain    Branched-chain alpha-keto acid dehydrogenase    Human (Homo sapiens) GO:

Image Source: PDB

1ols A - percentage of sequence identity: 99