PDB: 1ook Compound: human alpha thrombin Classification: HYDROLASE Entry date in PDB: 2003-07-22 Resolution [Å]: 2.30 R-Factor: 0.212

CHAIN: A SWISS-PROT/TREMBL: P00734    KEYWORD: 3D-structure    Acute phase    Blood coagulation    Calcium-binding    Disease mutation    Gamma-carboxyglutamic acid    Glycoprotein    Hydrolase    Kringle    Plasma    Polymorphism    Repeat    Serine protease    Signal    Vitamin K    Zymogen    EC: 3.4.21.5 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Thrombin    Human (Homo sapiens) GO:  extracellular region    calcium ion binding    chymotrypsin activity    thrombin activity    trypsin activity    blood coagulation    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P00734    KEYWORD: 3D-structure    Acute phase    Blood coagulation    Calcium-binding    Disease mutation    Gamma-carboxyglutamic acid    Glycoprotein    Hydrolase    Kringle    Plasma    Polymorphism    Repeat    Serine protease    Signal    Vitamin K    Zymogen    EC: 3.4.21.5 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Thrombin    Human (Homo sapiens) GO:  extracellular region    calcium ion binding    chymotrypsin activity    thrombin activity    trypsin activity    blood coagulation    proteolysis and peptidolysis    CHAIN: G SWISS-PROT/TREMBL: P07359    KEYWORD: 3D-structure    Bernard Soulier syndrome    Blood coagulation    Cell adhesion    Disease mutation    Glycoprotein    Hemostasis    Leucine-rich repeat    Platelet    Polymorphism    Repeat    Signal    Sulfation    Transmembrane    von Willebrand disease    SCOP: c.10.2.7 Alpha and beta proteins (a/b)    Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)    L domain-like    Ngr ectodomain-like    von Willebrand factor binding domain of glycoprotein Ib alpha    Human (Homo sapiens) GO:

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1etr H - percentage of sequence identity: 87
1h8d H - percentage of sequence identity: 97
1jou B - percentage of sequence identity: 99
1ucy H - percentage of sequence identity: 85
1vr1 H - percentage of sequence identity: 96
2hnt F - percentage of sequence identity: 100
null nu - percentage of sequence identity: 0