PDB: 1oqs Compound: phospholipase a2 rv-7 Classification: HYDROLASE Entry date in PDB: 2003-09-30 Resolution [Å]: 1.90 R-Factor: 0.223

CHAIN: A SWISS-PROT/TREMBL: P31100    KEYWORD: Calcium    Hydrolase    Lipid degradation    Multigene family    Neurotoxin    Postsynaptic neurotoxin    Signal    Toxin    EC: 3.1.1.4 SCOP: a.133.1.2 All alpha proteins    Phospholipase A2, PLA2    Phospholipase A2, PLA2    Vertebrate phospholipase A2    Snake phospholipase A2    Siamese russell's viper (Daboia russelli siamensis), RV7 inhibitory subunit GO:  calcium ion binding    phospholipase A2 activity    lipid catabolism    CHAIN: B SWISS-PROT/TREMBL: Q02471    KEYWORD: Calcium    Hydrolase    Lipid degradation    Multigene family    Neurotoxin    Postsynaptic neurotoxin    Presynaptic neurotoxin    Signal    Toxin    EC: 3.1.1.4 SCOP: a.133.1.2 All alpha proteins    Phospholipase A2, PLA2    Phospholipase A2, PLA2    Vertebrate phospholipase A2    Snake phospholipase A2    Siamese russell's viper (Daboia russelli siamensis), RV4 catalytic subunit GO:  calcium ion binding    phospholipase A2 activity    lipid catabolism    CHAIN: C SWISS-PROT/TREMBL: P31100    KEYWORD: Calcium    Hydrolase    Lipid degradation    Multigene family    Neurotoxin    Postsynaptic neurotoxin    Signal    Toxin    EC: 3.1.1.4 SCOP: a.133.1.2 All alpha proteins    Phospholipase A2, PLA2    Phospholipase A2, PLA2    Vertebrate phospholipase A2    Snake phospholipase A2    Siamese russell's viper (Daboia russelli siamensis), RV7 inhibitory subunit GO:  calcium ion binding    phospholipase A2 activity    lipid catabolism    CHAIN: D SWISS-PROT/TREMBL: Q02471    KEYWORD: Calcium    Hydrolase    Lipid degradation    Multigene family    Neurotoxin    Postsynaptic neurotoxin    Presynaptic neurotoxin    Signal    Toxin    EC: 3.1.1.4 SCOP: a.133.1.2 All alpha proteins    Phospholipase A2, PLA2    Phospholipase A2, PLA2    Vertebrate phospholipase A2    Snake phospholipase A2    Siamese russell's viper (Daboia russelli siamensis), RV4 catalytic subunit GO:  calcium ion binding    phospholipase A2 activity    lipid catabolism    CHAIN: E SWISS-PROT/TREMBL: P31100    KEYWORD: Calcium    Hydrolase    Lipid degradation    Multigene family    Neurotoxin    Postsynaptic neurotoxin    Signal    Toxin    EC: 3.1.1.4 SCOP: a.133.1.2 All alpha proteins    Phospholipase A2, PLA2    Phospholipase A2, PLA2    Vertebrate phospholipase A2    Snake phospholipase A2    Siamese russell's viper (Daboia russelli siamensis), RV7 inhibitory subunit GO:  calcium ion binding    phospholipase A2 activity    lipid catabolism    CHAIN: F SWISS-PROT/TREMBL: Q02471    KEYWORD: Calcium    Hydrolase    Lipid degradation    Multigene family    Neurotoxin    Postsynaptic neurotoxin    Presynaptic neurotoxin    Signal    Toxin    EC: 3.1.1.4 SCOP: a.133.1.2 All alpha proteins    Phospholipase A2, PLA2    Phospholipase A2, PLA2    Vertebrate phospholipase A2    Snake phospholipase A2    Siamese russell's viper (Daboia russelli siamensis), RV4 catalytic subunit GO:  calcium ion binding    phospholipase A2 activity    lipid catabolism    CHAIN: G SWISS-PROT/TREMBL: P31100    KEYWORD: Calcium    Hydrolase    Lipid degradation    Multigene family    Neurotoxin    Postsynaptic neurotoxin    Signal    Toxin    EC: 3.1.1.4 SCOP: a.133.1.2 All alpha proteins    Phospholipase A2, PLA2    Phospholipase A2, PLA2    Vertebrate phospholipase A2    Snake phospholipase A2    Siamese russell's viper (Daboia russelli siamensis), RV7 inhibitory subunit GO:  calcium ion binding    phospholipase A2 activity    lipid catabolism    CHAIN: H SWISS-PROT/TREMBL: Q02471    KEYWORD: Calcium    Hydrolase    Lipid degradation    Multigene family    Neurotoxin    Postsynaptic neurotoxin    Presynaptic neurotoxin    Signal    Toxin    EC: 3.1.1.4 SCOP: a.133.1.2 All alpha proteins    Phospholipase A2, PLA2    Phospholipase A2, PLA2    Vertebrate phospholipase A2    Snake phospholipase A2    Siamese russell's viper (Daboia russelli siamensis), RV4 catalytic subunit GO:  calcium ion binding    phospholipase A2 activity    lipid catabolism

Image Source: PDB

Loops in ArchDB95 clusters

1oqs_A_81 - EH => SUBCLASS : 4.6.3
1oqs_B_40 - HE => SUBCLASS : 10.3.1
1oqs_A_40 - HE => SUBCLASS : 10.4.1
1oqs_B_75 - HA => SUBCLASS : 2.1.1

Loops in ArchDB-EC clusters

1oqs_A_40 - HE => SUBCLASS : 10.5.1

Loops not clustered in ArchDB

1oqs_B_29 - EH
1oqs_B_81 - EH
1oqs_A_75 - HA
1oqs_B_24 - HA
1oqs_A_75 - HA
1oqs_B_24 - HA
1oqs_B_75 - HA
1oqs_B_2 - HE
1oqs_A_2 - HH

1aok A - percentage of sequence identity: 91
1aok B - percentage of sequence identity: 62
1jlt A - percentage of sequence identity: 92
1jlt B - percentage of sequence identity: 65
1oqs A - percentage of sequence identity: 100
1oqs B - percentage of sequence identity: 65
1oqs C - percentage of sequence identity: 100
1oqs D - percentage of sequence identity: 65
1oqs E - percentage of sequence identity: 100
1oqs F - percentage of sequence identity: 65
1oqs G - percentage of sequence identity: 100
1oqs H - percentage of sequence identity: 65
1oz6 A - percentage of sequence identity: 65
1q5t A - percentage of sequence identity: 90
1q5t B - percentage of sequence identity: 90
1rgb A - percentage of sequence identity: 65
1rgb B - percentage of sequence identity: 65
1rgb K - percentage of sequence identity: 65
1rgb L - percentage of sequence identity: 65
1vap A - percentage of sequence identity: 60
1vap B - percentage of sequence identity: 60
1vip - - percentage of sequence identity: 65
1vpi - - percentage of sequence identity: 93