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Information on 1os2

PDB: 1os2
Compound: macrophage metalloelastase
Classification: HYDROLASE
Entry date in PDB: 2003-08-05
Resolution [Å]: 2.15
R-Factor: 0.215

CHAIN: A

SWISS-PROT/TREMBL: P39900
   KEYWORD: 3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen    3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen
EC: 3.4.24.65
SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Macrophage elastase (MMP-12)    Human (Homo sapiens)
GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis

CHAIN: B

SWISS-PROT/TREMBL: P39900
   KEYWORD: 3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen    3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen
EC: 3.4.24.65
SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Macrophage elastase (MMP-12)    Human (Homo sapiens)
GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis

CHAIN: C

SWISS-PROT/TREMBL: P39900
   KEYWORD: 3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen    3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen
EC: 3.4.24.65
SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Macrophage elastase (MMP-12)    Human (Homo sapiens)
GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis

CHAIN: D

SWISS-PROT/TREMBL: P39900
   KEYWORD: 3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen    3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen
EC: 3.4.24.65
SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Macrophage elastase (MMP-12)    Human (Homo sapiens)
GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis

CHAIN: E

SWISS-PROT/TREMBL: P39900
   KEYWORD: 3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen    3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen
EC: 3.4.24.65
SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Macrophage elastase (MMP-12)    Human (Homo sapiens)
GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis

CHAIN: F

SWISS-PROT/TREMBL: P39900
   KEYWORD: 3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen    3D-structure    Calcium-binding    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen
EC: 3.4.24.65
SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Macrophage elastase (MMP-12)    Human (Homo sapiens)
GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis

1os2 Image

Image Source: PDB

Homologous structures to 1os2 classified in ArchDB

1jk3 A - percentage of sequence identity: 98