PDB: 1ovl Compound: orphan nuclear receptor nurr1 (mse 414, 496, 511) Classification: TRANSCRIPTION Entry date in PDB: 2003-06-03 Resolution [Å]: 2.20 R-Factor: 0.217

CHAIN: A SWISS-PROT/TREMBL: P43354    KEYWORD: 3D-structure    DNA-binding    Nuclear protein    Receptor    Transcription regulation    Zinc-finger    SCOP: a.123.1.1 All alpha proteins    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Orphan nuclear receptor NURR1    Human (Homo sapiens) GO:  nucleus    DNA binding    ligand-dependent nuclear receptor activity    steroid hormone receptor activity    transcription factor activity    regulation of transcription, DNA-dependent    CHAIN: B SWISS-PROT/TREMBL: P43354    KEYWORD: 3D-structure    DNA-binding    Nuclear protein    Receptor    Transcription regulation    Zinc-finger    SCOP: a.123.1.1 All alpha proteins    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Orphan nuclear receptor NURR1    Human (Homo sapiens) GO:  nucleus    DNA binding    ligand-dependent nuclear receptor activity    steroid hormone receptor activity    transcription factor activity    regulation of transcription, DNA-dependent    CHAIN: C SWISS-PROT/TREMBL: P43354    KEYWORD: 3D-structure    DNA-binding    Nuclear protein    Receptor    Transcription regulation    Zinc-finger    SCOP: a.123.1.1 All alpha proteins    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Orphan nuclear receptor NURR1    Human (Homo sapiens) GO:  nucleus    DNA binding    ligand-dependent nuclear receptor activity    steroid hormone receptor activity    transcription factor activity    regulation of transcription, DNA-dependent    CHAIN: D SWISS-PROT/TREMBL: P43354    KEYWORD: 3D-structure    DNA-binding    Nuclear protein    Receptor    Transcription regulation    Zinc-finger    SCOP: a.123.1.1 All alpha proteins    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Orphan nuclear receptor NURR1    Human (Homo sapiens) GO:  nucleus    DNA binding    ligand-dependent nuclear receptor activity    steroid hormone receptor activity    transcription factor activity    regulation of transcription, DNA-dependent    CHAIN: E SWISS-PROT/TREMBL: P43354    KEYWORD: 3D-structure    DNA-binding    Nuclear protein    Receptor    Transcription regulation    Zinc-finger    SCOP: a.123.1.1 All alpha proteins    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Orphan nuclear receptor NURR1    Human (Homo sapiens) GO:  nucleus    DNA binding    ligand-dependent nuclear receptor activity    steroid hormone receptor activity    transcription factor activity    regulation of transcription, DNA-dependent    CHAIN: F SWISS-PROT/TREMBL: P43354    KEYWORD: 3D-structure    DNA-binding    Nuclear protein    Receptor    Transcription regulation    Zinc-finger    SCOP: a.123.1.1 All alpha proteins    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Nuclear receptor ligand-binding domain    Orphan nuclear receptor NURR1    Human (Homo sapiens) GO:  nucleus    DNA binding    ligand-dependent nuclear receptor activity    steroid hormone receptor activity    transcription factor activity    regulation of transcription, DNA-dependent

Image Source: PDB

Loops in ArchDB95 clusters

1ovl_A_551 - HH => SUBCLASS : 6.1.1
1ovl_A_400 - HH => SUBCLASS : 8.1.1
1ovl_E_416 - HH => SUBCLASS : 8.1.1
1ovl_E_416 - HH => SUBCLASS : 8.1.2
1ovl_A_432 - HE => SUBCLASS : 6.45.1
1ovl_E_432 - HE => SUBCLASS : 6.45.1
1ovl_A_461 - HA => SUBCLASS : 3.1.1

Loops not clustered in ArchDB

1ovl_A_469 - EH
1ovl_E_469 - EH
1ovl_E_461 - HA
1ovl_E_521 - HH
1ovl_E_500 - HH
1ovl_E_482 - HH
1ovl_E_472 - HH
1ovl_E_399 - HH
1ovl_E_364 - HH
1ovl_E_338 - HH
1ovl_A_521 - HH
1ovl_A_500 - HH
1ovl_A_482 - HH
1ovl_A_472 - HH
1ovl_A_364 - HH
1ovl_E_549 - HH

1cit A - percentage of sequence identity: 100
1ovl A - percentage of sequence identity: 100
1ovl B - percentage of sequence identity: 100
1ovl C - percentage of sequence identity: 100
1ovl D - percentage of sequence identity: 100
1ovl E - percentage of sequence identity: 100
1ovl F - percentage of sequence identity: 100
1yje A - percentage of sequence identity: 62