PDB: 1p4o Compound: insulin-like growth factor i receptor protein Classification: HORMONE/GROWTH FACTOR Entry date in PDB: 2003-04-29 Resolution [Å]: 1.50 R-Factor: 0.209

CHAIN: A SWISS-PROT/TREMBL: P08069    KEYWORD: 3D-structure    ATP-binding    Glycoprotein    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Insulin-like growth factor 1 receptor    Human (Homo sapiens) GO:  membrane    ATP binding    epidermal growth factor receptor activity    protein kinase activity    protein-tyrosine kinase activity    transmembrane receptor protein tyrosine kinase activity    protein amino acid phosphorylation    transmembrane receptor protein tyrosine kinase signaling pathway    CHAIN: B SWISS-PROT/TREMBL: P08069    KEYWORD: 3D-structure    ATP-binding    Glycoprotein    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Insulin-like growth factor 1 receptor    Human (Homo sapiens) GO:  membrane    ATP binding    epidermal growth factor receptor activity    protein kinase activity    protein-tyrosine kinase activity    transmembrane receptor protein tyrosine kinase activity    protein amino acid phosphorylation    transmembrane receptor protein tyrosine kinase signaling pathway

Image Source: PDB

Loops in ArchDB40 clusters

1p4o_A_1079 - HE => SUBCLASS : 11.1.1
1p4o_A_1136 - HA => SUBCLASS : 2.1.1
1p4o_A_969 - HA => SUBCLASS : 2.2.10
1p4o_A_1111 - HA => SUBCLASS : 3.1.1
1p4o_A_969 - HA => SUBCLASS : 6.7.1
1p4o_A_995 - EH => SUBCLASS : 5.1.7
1p4o_A_1143 - EH => SUBCLASS : 5.4.1
1p4o_A_1046 - EH => SUBCLASS : 6.9.1
1p4o_A_1151 - HH => SUBCLASS : 4.7.1
1p4o_A_1188 - HH => SUBCLASS : 11.1.1

Loops in ArchDB95 clusters

1p4o_A_995 - EH => SUBCLASS : 5.1.6
1p4o_A_1143 - EH => SUBCLASS : 5.2.2
1p4o_A_1046 - EH => SUBCLASS : 6.7.1
1p4o_A_1229 - HH => SUBCLASS : 2.1.45
1p4o_A_1151 - HH => SUBCLASS : 4.3.1
1p4o_A_1209 - HH => SUBCLASS : 9.1.2
1p4o_A_1161 - HH => SUBCLASS : 10.8.1
1p4o_A_1188 - HH => SUBCLASS : 11.1.1
1p4o_A_1011 - HE => SUBCLASS : 8.2.1
1p4o_A_1079 - HE => SUBCLASS : 11.1.1
1p4o_A_969 - HA => SUBCLASS : 2.2.2
1p4o_A_1111 - HA => SUBCLASS : 3.1.1
1p4o_A_969 - HA => SUBCLASS : 4.50.1
1p4o_A_1035 - HA => SUBCLASS : 6.17.1

Loops in ArchDB-EC clusters

1p4o_A_1188 - HH => SUBCLASS : 11.1.1

Loops not clustered in ArchDB

1p4o_A_1119 - AR
1p4o_A_1119 - AR
1p4o_A_982 - HA
1p4o_A_969 - HA
1p4o_A_982 - HA
1p4o_A_1035 - HA
1p4o_A_1111 - HA
1p4o_A_1136 - HA
1p4o_A_1057 - HH

1gag A - percentage of sequence identity: 79
1i44 A - percentage of sequence identity: 79
1ir3 A - percentage of sequence identity: 79
1irk - - percentage of sequence identity: 79
1jqh A - percentage of sequence identity: 99
1jqh B - percentage of sequence identity: 99
1jqh C - percentage of sequence identity: 99
1k3a A - percentage of sequence identity: 98
1m7n A - percentage of sequence identity: 99
1m7n B - percentage of sequence identity: 99
1p14 A - percentage of sequence identity: 79
1p4o A - percentage of sequence identity: 100
1p4o B - percentage of sequence identity: 100
1rqq A - percentage of sequence identity: 79
1rqq B - percentage of sequence identity: 79
2auh A - percentage of sequence identity: 79
2b4s B - percentage of sequence identity: 79
2b4s D - percentage of sequence identity: 79