PDB: 1pjl Compound: nad-dependent malic enzyme, mitochondrial Classification: OXIDOREDUCTASE Entry date in PDB: 2003-06-17 Resolution [Å]: 2.90 R-Factor: 0.204

CHAIN: A SWISS-PROT/TREMBL: P23368    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    EC: 1.1.1.38 SCOP: c.2.1.7 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Aminoacid dehydrogenase-like, C-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) SCOP: c.58.1.3 Alpha and beta proteins (a/b)    Aminoacid dehydrogenase-like, N-terminal domain    Aminoacid dehydrogenase-like, N-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) GO:  malic enzyme activity    malate metabolism    CHAIN: B SWISS-PROT/TREMBL: P23368    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    EC: 1.1.1.38 SCOP: c.2.1.7 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Aminoacid dehydrogenase-like, C-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) SCOP: c.58.1.3 Alpha and beta proteins (a/b)    Aminoacid dehydrogenase-like, N-terminal domain    Aminoacid dehydrogenase-like, N-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) GO:  malic enzyme activity    malate metabolism    CHAIN: C SWISS-PROT/TREMBL: P23368    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    EC: 1.1.1.38 SCOP: c.2.1.7 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Aminoacid dehydrogenase-like, C-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) SCOP: c.58.1.3 Alpha and beta proteins (a/b)    Aminoacid dehydrogenase-like, N-terminal domain    Aminoacid dehydrogenase-like, N-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) GO:  malic enzyme activity    malate metabolism    CHAIN: D SWISS-PROT/TREMBL: P23368    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    EC: 1.1.1.38 SCOP: c.2.1.7 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Aminoacid dehydrogenase-like, C-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) SCOP: c.58.1.3 Alpha and beta proteins (a/b)    Aminoacid dehydrogenase-like, N-terminal domain    Aminoacid dehydrogenase-like, N-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) GO:  malic enzyme activity    malate metabolism    CHAIN: E SWISS-PROT/TREMBL: P23368    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    EC: 1.1.1.38 SCOP: c.2.1.7 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Aminoacid dehydrogenase-like, C-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) SCOP: c.58.1.3 Alpha and beta proteins (a/b)    Aminoacid dehydrogenase-like, N-terminal domain    Aminoacid dehydrogenase-like, N-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) GO:  malic enzyme activity    malate metabolism    CHAIN: F SWISS-PROT/TREMBL: P23368    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    EC: 1.1.1.38 SCOP: c.2.1.7 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Aminoacid dehydrogenase-like, C-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) SCOP: c.58.1.3 Alpha and beta proteins (a/b)    Aminoacid dehydrogenase-like, N-terminal domain    Aminoacid dehydrogenase-like, N-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) GO:  malic enzyme activity    malate metabolism    CHAIN: G SWISS-PROT/TREMBL: P23368    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    EC: 1.1.1.38 SCOP: c.2.1.7 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Aminoacid dehydrogenase-like, C-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) SCOP: c.58.1.3 Alpha and beta proteins (a/b)    Aminoacid dehydrogenase-like, N-terminal domain    Aminoacid dehydrogenase-like, N-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) GO:  malic enzyme activity    malate metabolism    CHAIN: H SWISS-PROT/TREMBL: P23368    KEYWORD: 3D-structure    Mitochondrion    NAD    Oxidoreductase    Transit peptide    EC: 1.1.1.38 SCOP: c.2.1.7 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Aminoacid dehydrogenase-like, C-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) SCOP: c.58.1.3 Alpha and beta proteins (a/b)    Aminoacid dehydrogenase-like, N-terminal domain    Aminoacid dehydrogenase-like, N-terminal domain    Mitochondrial NAD(P)-dependent malic enzyme    Mitochondrial NAD(P)-dependent malic enzyme    Human (Homo sapiens) GO:  malic enzyme activity    malate metabolism

Image Source: PDB

1gz3 A - percentage of sequence identity: 99
1pj3 A - percentage of sequence identity: 100