PDB: 1pl0 Compound: bifunctional purine biosynthesis protein purh Classification: TRANSFERASE, HYDROLASE Entry date in PDB: 2004-04-27 Resolution [Å]: 2.60 R-Factor: 0.213

CHAIN: A SWISS-PROT/TREMBL: P31939    KEYWORD: Hydrolase    Multifunctional enzyme    Purine biosynthesis    Transferase    EC: 2.1.2.3 SCOP: c.24.1.3 Alpha and beta proteins (a/b)    Methylglyoxal synthase-like    Methylglyoxal synthase-like    Inosicase    IMP cyclohydrolase domain of bifunctional purine biosynthesis enzyme ATIC    Human (Homo sapiens) SCOP: c.97.2.1 Alpha and beta proteins (a/b)    Cytidine deaminase-like    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    Human (Homo sapiens) GO:  IMP cyclohydrolase activity    phosphoribosylaminoimidazolecarboxamide formyltransferase activity    purine nucleotide biosynthesis    CHAIN: B SWISS-PROT/TREMBL: P31939    KEYWORD: Hydrolase    Multifunctional enzyme    Purine biosynthesis    Transferase    EC: 2.1.2.3 SCOP: c.24.1.3 Alpha and beta proteins (a/b)    Methylglyoxal synthase-like    Methylglyoxal synthase-like    Inosicase    IMP cyclohydrolase domain of bifunctional purine biosynthesis enzyme ATIC    Human (Homo sapiens) SCOP: c.97.2.1 Alpha and beta proteins (a/b)    Cytidine deaminase-like    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    Human (Homo sapiens) GO:  IMP cyclohydrolase activity    phosphoribosylaminoimidazolecarboxamide formyltransferase activity    purine nucleotide biosynthesis    CHAIN: C SWISS-PROT/TREMBL: P31939    KEYWORD: Hydrolase    Multifunctional enzyme    Purine biosynthesis    Transferase    EC: 2.1.2.3 SCOP: c.24.1.3 Alpha and beta proteins (a/b)    Methylglyoxal synthase-like    Methylglyoxal synthase-like    Inosicase    IMP cyclohydrolase domain of bifunctional purine biosynthesis enzyme ATIC    Human (Homo sapiens) SCOP: c.97.2.1 Alpha and beta proteins (a/b)    Cytidine deaminase-like    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    Human (Homo sapiens) GO:  IMP cyclohydrolase activity    phosphoribosylaminoimidazolecarboxamide formyltransferase activity    purine nucleotide biosynthesis    CHAIN: D SWISS-PROT/TREMBL: P31939    KEYWORD: Hydrolase    Multifunctional enzyme    Purine biosynthesis    Transferase    EC: 2.1.2.3 SCOP: c.24.1.3 Alpha and beta proteins (a/b)    Methylglyoxal synthase-like    Methylglyoxal synthase-like    Inosicase    IMP cyclohydrolase domain of bifunctional purine biosynthesis enzyme ATIC    Human (Homo sapiens) SCOP: c.97.2.1 Alpha and beta proteins (a/b)    Cytidine deaminase-like    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC    Human (Homo sapiens) GO:  IMP cyclohydrolase activity    phosphoribosylaminoimidazolecarboxamide formyltransferase activity    purine nucleotide biosynthesis

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1g8m A - percentage of sequence identity: 83
1pkx A - percentage of sequence identity: 100