PDB: 1pvh Compound: interleukin-6 receptor beta chain Classification: SIGNALING PROTEIN/CYTOKINE Entry date in PDB: 2003-10-14 Resolution [Å]: 2.50 R-Factor: 0.248

CHAIN: A SWISS-PROT/TREMBL: P40189    KEYWORD: 3D-structure    Alternative splicing    Glycoprotein    Immunoglobulin domain    Receptor    Repeat    Signal    Transmembrane    SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Cytokine receptor gp130 cytokine-binding domains    Human (Homo sapiens) SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Cytokine receptor gp130 cytokine-binding domains    Human (Homo sapiens) GO:  membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity    CHAIN: B SWISS-PROT/TREMBL: P40189    KEYWORD: 3D-structure    Alternative splicing    Glycoprotein    Immunoglobulin domain    Receptor    Repeat    Signal    Transmembrane    SCOP: a.26.1.1 All alpha proteins    4-helical cytokines    4-helical cytokines    Long-chain cytokines    Leukemia inhibitory factor (LIF)    Human (Homo sapiens) GO:  extracellular region    cytokine activity    leukemia inhibitory factor receptor binding    immune response    CHAIN: C SWISS-PROT/TREMBL: P15018    KEYWORD: 3D-structure    Cytokine    Glycoprotein    Growth factor    Signal    SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Cytokine receptor gp130 cytokine-binding domains    Human (Homo sapiens) SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Cytokine receptor gp130 cytokine-binding domains    Human (Homo sapiens) GO:  membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity    CHAIN: D SWISS-PROT/TREMBL: P15018    KEYWORD: 3D-structure    Cytokine    Glycoprotein    Growth factor    Signal    SCOP: a.26.1.1 All alpha proteins    4-helical cytokines    4-helical cytokines    Long-chain cytokines    Leukemia inhibitory factor (LIF)    Human (Homo sapiens) GO:  extracellular region    cytokine activity    leukemia inhibitory factor receptor binding    immune response

Image Source: PDB

Loops in ArchDB95 clusters

1pvh_B_22 - HH => SUBCLASS : 3.34.1
1pvh_B_76 - HH => SUBCLASS : 4.2.3

Loops not clustered in ArchDB

1pvh_B_56 - HH
1pvh_B_109 - HH

1a7m - - percentage of sequence identity: 84
1bqu A - percentage of sequence identity: 100
1emr A - percentage of sequence identity: 98
1i1r A - percentage of sequence identity: 100
1lki - - percentage of sequence identity: 76
1pvh B - percentage of sequence identity: 100
1pvh D - percentage of sequence identity: 100