PDB: 1pwu Compound: lethal factor Classification: HYDROLASE Entry date in PDB: 2004-02-03 Resolution [Å]: 2.70 R-Factor: 0.235

CHAIN: A SWISS-PROT/TREMBL: P15917    KEYWORD: 3D-structure    Hydrolase    Metal-binding    Metalloprotease    Plasmid    Repeat    Signal    Toxin    Virulence    Zinc    EC: 3.4.24.83 SCOP: d.92.1.14 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Anthrax toxin lethal factor, N- and C-terminal domains    Anthrax toxin lethal factor, N- and C-terminal domains    Bacillus anthracis SCOP: d.92.1.14 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Anthrax toxin lethal factor, N- and C-terminal domains    Anthrax toxin lethal factor, N- and C-terminal domains    Bacillus anthracis SCOP: d.166.1.1 Alpha and beta proteins (a+b)    ADP-ribosylation    ADP-ribosylation    ADP-ribosylating toxins    Anthrax toxin lethal factor, middle domain    Bacillus anthracis GO:  extracellular region    metallopeptidase activity    zinc ion binding    pathogenesis    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P15917    KEYWORD: 3D-structure    Hydrolase    Metal-binding    Metalloprotease    Plasmid    Repeat    Signal    Toxin    Virulence    Zinc    EC: 3.4.24.83 SCOP: d.92.1.14 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Anthrax toxin lethal factor, N- and C-terminal domains    Anthrax toxin lethal factor, N- and C-terminal domains    Bacillus anthracis SCOP: d.92.1.14 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Anthrax toxin lethal factor, N- and C-terminal domains    Anthrax toxin lethal factor, N- and C-terminal domains    Bacillus anthracis SCOP: d.166.1.1 Alpha and beta proteins (a+b)    ADP-ribosylation    ADP-ribosylation    ADP-ribosylating toxins    Anthrax toxin lethal factor, middle domain    Bacillus anthracis GO:  extracellular region    metallopeptidase activity    zinc ion binding    pathogenesis    proteolysis and peptidolysis

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1j7n A - percentage of sequence identity: 99