PDB: 1qme Compound: penicillin-binding protein 2x Classification: PEPTIDOGLYCAN SYNTHESIS Entry date in PDB: 2000-05-25 Resolution [Å]: 2.40 R-Factor: 0.197

CHAIN: A SWISS-PROT/TREMBL: P14677    KEYWORD: 3D-structure    Antibiotic resistance    Cell division    Cell wall    Complete proteome    Peptidoglycan synthesis    Transmembrane    SCOP: d.11.1.1 Alpha and beta proteins (a+b)    Penicillin-binding protein 2x (pbp-2x), c-terminal domain    Penicillin-binding protein 2x (pbp-2x), c-terminal domain    Penicillin-binding protein 2x (pbp-2x), c-terminal domain    Penicillin-binding protein 2x (pbp-2x), c-terminal domain    Streptococcus pneumoniae SCOP: d.11.1.1 Alpha and beta proteins (a+b)    Penicillin-binding protein 2x (pbp-2x), c-terminal domain    Penicillin-binding protein 2x (pbp-2x), c-terminal domain    Penicillin-binding protein 2x (pbp-2x), c-terminal domain    Penicillin-binding protein 2x (pbp-2x), c-terminal domain    Streptococcus pneumoniae SCOP: d.175.1.1 Alpha and beta proteins (a+b)    Penicillin binding protein dimerisation domain    Penicillin binding protein dimerisation domain    Penicillin binding protein dimerisation domain    Penicillin-binding protein 2x (pbp-2x), N-terminal domain    Streptococcus pneumoniae SCOP: e.3.1.1 Multi-domain proteins (alpha and beta)    beta-lactamase/transpeptidase-like    beta-lactamase/transpeptidase-like    beta-Lactamase/D-ala carboxypeptidase    Penicillin-binding protein 2x (pbp-2x), transpeptidase domain    Streptococcus pneumoniae GO:  penicillin binding    cell wall biosynthesis (sensu Bacteria)

Image Source: PDB

Loops in ArchDB40 clusters

1qme_A_646 - HE => SUBCLASS : 1.1.1
1qme_A_704 - HE => SUBCLASS : 1.1.1
1qme_A_267 - HE => SUBCLASS : 3.1.2
1qme_A_267 - HE => SUBCLASS : 3.1.5
1qme_A_364 - HA => SUBCLASS : 2.1.1
1qme_A_201 - HA => SUBCLASS : 3.1.1
1qme_A_480 - HA => SUBCLASS : 4.1.1
1qme_A_528 - HA => SUBCLASS : 4.1.1
1qme_A_288 - HA => SUBCLASS : 4.1.2
1qme_A_528 - HA => SUBCLASS : 4.1.2
1qme_A_79 - HA => SUBCLASS : 5.1.6
1qme_A_79 - HA => SUBCLASS : 5.3.1
1qme_A_79 - HA => SUBCLASS : 5.3.2
1qme_A_369 - EH => SUBCLASS : 1.1.5
1qme_A_369 - EH => SUBCLASS : 1.1.21
1qme_A_260 - EH => SUBCLASS : 3.6.3
1qme_A_358 - AR => SUBCLASS : 2.4.2
1qme_A_358 - AR => SUBCLASS : 3.7.5
1qme_A_474 - AR => SUBCLASS : 4.16.1
1qme_A_490 - AR => SUBCLASS : 4.26.2
1qme_A_388 - HH => SUBCLASS : 2.2.5

Loops in ArchDB95 clusters

1qme_A_369 - EH => SUBCLASS : 1.1.3
1qme_A_369 - EH => SUBCLASS : 1.1.16
1qme_A_260 - EH => SUBCLASS : 3.4.3
1qme_A_358 - AR => SUBCLASS : 3.11.1
1qme_A_474 - AR => SUBCLASS : 4.16.3
1qme_A_490 - AR => SUBCLASS : 4.24.1
1qme_A_397 - HH => SUBCLASS : 1.4.1
1qme_A_388 - HH => SUBCLASS : 2.2.3
1qme_A_646 - HE => SUBCLASS : 1.1.1
1qme_A_704 - HE => SUBCLASS : 1.1.1
1qme_A_267 - HE => SUBCLASS : 3.1.2
1qme_A_364 - HA => SUBCLASS : 2.1.1
1qme_A_201 - HA => SUBCLASS : 3.1.1
1qme_A_528 - HA => SUBCLASS : 4.1.1
1qme_A_480 - HA => SUBCLASS : 4.1.1
1qme_A_288 - HA => SUBCLASS : 4.1.2
1qme_A_79 - HA => SUBCLASS : 4.3.2
1qme_A_79 - HA => SUBCLASS : 5.1.1
1qme_A_288 - HA => SUBCLASS : 5.5.1

Loops not clustered in ArchDB

1qme_A_534 - AR
1qme_A_659 - AR
1qme_A_717 - AR
1qme_A_498 - EH
1qme_A_211 - EH
1qme_A_185 - EH
1qme_A_385 - EH
1qme_A_301 - EH
1qme_A_583 - EH
1qme_A_685 - EH
1qme_A_86 - HA
1qme_A_726 - HA
1qme_A_669 - HA
1qme_A_568 - HA
1qme_A_545 - HA
1qme_A_505 - HE
1qme_A_458 - HE
1qme_A_374 - HE
1qme_A_340 - HE
1qme_A_224 - HE
1qme_A_195 - HE
1qme_A_218 - HH
1qme_A_409 - HH
1qme_A_442 - HH
1qme_A_597 - HH

1k25 A - percentage of sequence identity: 88
1k25 B - percentage of sequence identity: 88
1k25 C - percentage of sequence identity: 88
1k25 D - percentage of sequence identity: 88
1pmd - - percentage of sequence identity: 100
1pyy A - percentage of sequence identity: 99
1qmf A - percentage of sequence identity: 100
1rp5 A - percentage of sequence identity: 96
1rp5 B - percentage of sequence identity: 96