PDB: 1qxp Compound: mu-like calpain Classification: HYDROLASE CHIMERA Entry date in PDB: 2004-02-03 Resolution [Å]: 2.80 R-Factor: 0.233

CHAIN: A SWISS-PROT/TREMBL: P97571    KEYWORD: 3D-structure    Calcium-binding    Hydrolase    Thiol protease    3D-structure    Calcium-binding    Hydrolase    Multigene family    Repeat    Thiol protease    EC: 3.4.22.52 SCOP: a.39.1.8 All alpha proteins    EF Hand-like    EF-hand    Penta-EF-hand proteins    Calpain small (regulatory) subunit (domain VI)    Rat (Rattus norvegicus) SCOP: a.39.1.8 All alpha proteins    EF Hand-like    EF-hand    Penta-EF-hand proteins    Calpain large subunit, C-terminal domain (domain IV)    Rat (Rattus norvegicus), mu-type SCOP: b.14.1.1 All beta proteins    Calpain large subunit, middle domain (domain III)    Calpain large subunit, middle domain (domain III)    Calpain large subunit, middle domain (domain III)    Calpain large subunit, middle domain (domain III)    Rat (Rattus norvegicus), mu-type SCOP: d.3.1.3 Alpha and beta proteins (a+b)    Cysteine proteinases    Cysteine proteinases    Calpain large subunit, catalytic domain (domain II)    Calpain large subunit, catalytic domain (domain II)    Rat (Rattus norvegicus), mu-type GO:  intracellular    intracellular    calcium ion binding    calcium ion binding    calpain activity    calpain activity    cysteine-type endopeptidase activity    cysteine-type endopeptidase activity    proteolysis and peptidolysis    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P97571    KEYWORD: 3D-structure    Calcium-binding    Hydrolase    Thiol protease    3D-structure    Calcium-binding    Hydrolase    Multigene family    Repeat    Thiol protease    EC: 3.4.22.52 SCOP: a.39.1.8 All alpha proteins    EF Hand-like    EF-hand    Penta-EF-hand proteins    Calpain small (regulatory) subunit (domain VI)    Rat (Rattus norvegicus) SCOP: a.39.1.8 All alpha proteins    EF Hand-like    EF-hand    Penta-EF-hand proteins    Calpain large subunit, C-terminal domain (domain IV)    Rat (Rattus norvegicus), mu-type SCOP: b.14.1.1 All beta proteins    Calpain large subunit, middle domain (domain III)    Calpain large subunit, middle domain (domain III)    Calpain large subunit, middle domain (domain III)    Calpain large subunit, middle domain (domain III)    Rat (Rattus norvegicus), mu-type SCOP: d.3.1.3 Alpha and beta proteins (a+b)    Cysteine proteinases    Cysteine proteinases    Calpain large subunit, catalytic domain (domain II)    Calpain large subunit, catalytic domain (domain II)    Rat (Rattus norvegicus), mu-type GO:  intracellular    intracellular    calcium ion binding    calcium ion binding    calpain activity    calpain activity    cysteine-type endopeptidase activity    cysteine-type endopeptidase activity    proteolysis and peptidolysis    proteolysis and peptidolysis

Image Source: PDB

1kxr A - percentage of sequence identity: 96
1mdw A - percentage of sequence identity: 73