PDB: 1ra9 Compound: dihydrofolate reductase Classification: OXIDOREDUCTASE Entry date in PDB: 1996-12-23 Resolution [Å]: 1.55 R-Factor: 0.169

CHAIN: - SWISS-PROT/TREMBL: P00379    KEYWORD: 3D-structure    Complete proteome    Methotrexate resistance    NADP    One-carbon metabolism    Oxidoreductase    Trimethoprim resistance    EC: 1.5.1.3 SCOP: c.71.1.1 Alpha and beta proteins (a/b)    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductase, prokaryotic type    Escherichia coli GO:  dihydrofolate reductase activity    dihydrofolate reductase activity    dihydrofolate reductase activity    glycine biosynthesis    glycine biosynthesis    glycine biosynthesis    nucleotide biosynthesis    nucleotide biosynthesis    nucleotide biosynthesis

Image Source: PDB

Loops in ArchDB40 clusters

1ra9_*_97 - HE => SUBCLASS : 2.3.2
1ra9_*_25 - HE => SUBCLASS : 2.7.2
1ra9_*_133 - HA => SUBCLASS : 9.5.1
1ra9_*_73 - EH => SUBCLASS : 2.1.1
1ra9_*_91 - EH => SUBCLASS : 3.27.1

Loops in ArchDB95 clusters

1ra9_*_73 - EH => SUBCLASS : 2.1.1
1ra9_*_91 - EH => SUBCLASS : 3.40.1
1ra9_*_97 - HE => SUBCLASS : 2.2.7
1ra9_*_25 - HE => SUBCLASS : 3.8.2
1ra9_*_133 - HA => SUBCLASS : 9.5.1

Loops in ArchDB-EC clusters

1ra9_*_25 - HE => SUBCLASS : 2.8.1

Loops not clustered in ArchDB

1ra9_*_109 - AR
1ra9_*_123 - AR
1ra9_*_109 - AR
1ra9_*_2 - AR
1ra9_*_2 - AR
1ra9_*_123 - AR
1ra9_*_13 - EH
1ra9_*_40 - EH
1ra9_*_59 - HA
1ra9_*_59 - HA
1ra9_*_133 - HA
1ra9_*_78 - HE
1ra9_*_44 - HE

1ddr A - percentage of sequence identity: 99
1ddr B - percentage of sequence identity: 99
1dds A - percentage of sequence identity: 99
1dds B - percentage of sequence identity: 99
1dhi A - percentage of sequence identity: 99
1dhi B - percentage of sequence identity: 99
1dhj A - percentage of sequence identity: 98
1dhj B - percentage of sequence identity: 98
1dra A - percentage of sequence identity: 99
1dra B - percentage of sequence identity: 99
1drb A - percentage of sequence identity: 99
1drb B - percentage of sequence identity: 99
1dre - - percentage of sequence identity: 100
1drh - - percentage of sequence identity: 100
1dyh A - percentage of sequence identity: 100
1dyh B - percentage of sequence identity: 100
1dyi A - percentage of sequence identity: 100
1dyi B - percentage of sequence identity: 100
1dyj A - percentage of sequence identity: 100
1dyj B - percentage of sequence identity: 100
1jol A - percentage of sequence identity: 100
1jol B - percentage of sequence identity: 100
1jom - - percentage of sequence identity: 100
1ra1 - - percentage of sequence identity: 100
1ra2 - - percentage of sequence identity: 100
1ra3 - - percentage of sequence identity: 100
1ra8 - - percentage of sequence identity: 100
1rb2 A - percentage of sequence identity: 100
1rb2 B - percentage of sequence identity: 100
1rb3 A - percentage of sequence identity: 100
1rb3 B - percentage of sequence identity: 100
1rc4 - - percentage of sequence identity: 100
1rd7 A - percentage of sequence identity: 100
1rd7 B - percentage of sequence identity: 100
1re7 A - percentage of sequence identity: 100
1re7 B - percentage of sequence identity: 100
1rf7 - - percentage of sequence identity: 100
1rg7 - - percentage of sequence identity: 100
1rh3 - - percentage of sequence identity: 100
1rx1 - - percentage of sequence identity: 100
1rx2 - - percentage of sequence identity: 100
1rx3 - - percentage of sequence identity: 100
1rx4 - - percentage of sequence identity: 100
1rx5 - - percentage of sequence identity: 100
1rx6 - - percentage of sequence identity: 100
1rx7 - - percentage of sequence identity: 100
1rx8 - - percentage of sequence identity: 100
1rx9 - - percentage of sequence identity: 100
1tdr A - percentage of sequence identity: 99
1tdr B - percentage of sequence identity: 99
2drc A - percentage of sequence identity: 99
2drc B - percentage of sequence identity: 99
3drc A - percentage of sequence identity: 100
3drc B - percentage of sequence identity: 100
4dfr A - percentage of sequence identity: 99
4dfr B - percentage of sequence identity: 99
5dfr - - percentage of sequence identity: 100
6dfr - - percentage of sequence identity: 100
7dfr - - percentage of sequence identity: 100