PDB: 1rdr Compound: poliovirus 3d polymerase Classification: NUCLEOTIDYLTRANSFERASE Entry date in PDB: 1998-09-16 Resolution [Å]: 2.40 R-Factor: 0.244

CHAIN: - SWISS-PROT/TREMBL: P03300    KEYWORD: 3D-structure    Coat protein    Core protein    Hydrolase    Lipoprotein    Myristate    Polyprotein    RNA-directed RNA polymerase    Thiol protease    Transferase    EC: 2.7.7.48 SCOP: e.8.1.4 Multi-domain proteins (alpha and beta)    DNA/RNA polymerases    DNA/RNA polymerases    RNA-dependent RNA-polymerase    Viral RNA polymerase    Poliovirus type 1, strain Mahoney GO:  viral capsid    ATP binding    cysteine-type endopeptidase activity    helicase activity    nucleoside-triphosphatase activity    nucleotide binding    peptidase activity    picornain 3C activity    RNA binding    RNA helicase activity    RNA-directed RNA polymerase activity    structural molecule activity    proteolysis and peptidolysis    transcription    viral genome replication    viral life cycle

Image Source: PDB

Loops in ArchDB40 clusters

1rdr_*_377 - HA => SUBCLASS : 6.2.1
1rdr_*_388 - EH => SUBCLASS : 1.1.11
1rdr_*_403 - EH => SUBCLASS : 2.1.2
1rdr_*_233 - EH => SUBCLASS : 2.6.2
1rdr_*_329 - EH => SUBCLASS : 5.12.1
1rdr_*_329 - EH => SUBCLASS : 5.57.1
1rdr_*_237 - HH => SUBCLASS : 2.1.1
1rdr_*_237 - HH => SUBCLASS : 2.1.10

Loops in ArchDB95 clusters

1rdr_*_388 - EH => SUBCLASS : 1.1.9
1rdr_*_233 - EH => SUBCLASS : 1.4.2
1rdr_*_403 - EH => SUBCLASS : 2.1.5
1rdr_*_233 - EH => SUBCLASS : 2.6.4
1rdr_*_329 - EH => SUBCLASS : 5.10.1
1rdr_*_426 - HH => SUBCLASS : 1.1.33
1rdr_*_237 - HH => SUBCLASS : 2.1.1
1rdr_*_237 - HH => SUBCLASS : 2.1.38
1rdr_*_377 - HA => SUBCLASS : 6.3.1

Loops in ArchDB-EC clusters

1rdr_*_237 - HH => SUBCLASS : 2.1.7

Loops not clustered in ArchDB

1rdr_*_354 - AR
1rdr_*_228 - AR
1rdr_*_354 - AR
1rdr_*_228 - AR
1rdr_*_26 - EH
1rdr_*_324 - HA
1rdr_*_324 - HA
1rdr_*_377 - HA
1rdr_*_221 - HE
1rdr_*_293 - HE
1rdr_*_340 - HE
1rdr_*_394 - HE
1rdr_*_214 - HH
1rdr_*_72 - HH
1rdr_*_187 - HH
1rdr_*_440 - HH
1rdr_*_410 - HH
1rdr_*_192 - HH
1rdr_*_243 - HH

1ra6 A - percentage of sequence identity: 99
1ra7 A - percentage of sequence identity: 99
1raj A - percentage of sequence identity: 99
1tql A - percentage of sequence identity: 99
1xr5 A - percentage of sequence identity: 64