PDB: 1rkp Compound: cgmp-specific 3',5'-cyclic phosphodiesterase Classification: HYDROLASE Entry date in PDB: 2004-03-30 Resolution [Å]: 2.05 R-Factor: 0.220

CHAIN: A SWISS-PROT/TREMBL: O76074    KEYWORD: Allosteric enzyme    Alternative splicing    cGMP    cGMP-binding    Hydrolase    Magnesium    Metal-binding    Phosphorylation    Zinc    EC: 3.1.4.17 SCOP: a.125.1.1 All alpha proteins    PDEase    PDEase    PDEase    cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx    Human (Homo sapiens) GO:  3',5'-cyclic-nucleotide phosphodiesterase activity    catalytic activity    signal transduction

Image Source: PDB

Loops in ArchDB40 clusters

1rkp_A_706 - HH => SUBCLASS : 1.1.4
1rkp_A_749 - HH => SUBCLASS : 2.1.31
1rkp_A_584 - HH => SUBCLASS : 3.2.2
1rkp_A_673 - HH => SUBCLASS : 3.14.1

Loops in ArchDB95 clusters

1rkp_A_706 - HH => SUBCLASS : 1.1.4
1rkp_A_749 - HH => SUBCLASS : 2.1.27
1rkp_A_584 - HH => SUBCLASS : 3.1.2
1rkp_A_673 - HH => SUBCLASS : 3.10.1
1rkp_A_536 - HH => SUBCLASS : 5.16.1
1rkp_A_592 - HH => SUBCLASS : 9.24.1

Loops not clustered in ArchDB

1rkp_A_551 - HH
1rkp_A_812 - HH
1rkp_A_772 - HH
1rkp_A_725 - HH
1rkp_A_680 - HH
1rkp_A_664 - HH
1rkp_A_640 - HH
1rkp_A_615 - HH
1rkp_A_568 - HH
1rkp_A_825 - HH

1t9r A - percentage of sequence identity: 99
1t9s A - percentage of sequence identity: 94
1t9s B - percentage of sequence identity: 94
1tbf A - percentage of sequence identity: 94
1udt A - percentage of sequence identity: 99
1udu A - percentage of sequence identity: 99
1udu B - percentage of sequence identity: 99
1uho A - percentage of sequence identity: 99
1xoz A - percentage of sequence identity: 94
1xp0 A - percentage of sequence identity: 94