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Information on 1t2v
PDB: 1t2v
Compound: breast cancer type 1 susceptibility protein
Classification: ANTITUMOR PROTEIN
Entry date in PDB: 2004-05-11
Resolution [Å]: 3.30
R-Factor: 0.261


CHAIN: A
SWISS-PROT/TREMBL: P38398
   KEYWORD: 3D-structure    Anti-oncogene    Disease mutation    DNA repair    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Zinc-finger   
SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens)
SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens)
GO:  intracellular    nucleus    ubiquitin ligase complex    DNA binding    ubiquitin-protein ligase activity    zinc ion binding    DNA repair    protein ubiquitination   


CHAIN: B
SWISS-PROT/TREMBL: P38398
   KEYWORD: 3D-structure    Anti-oncogene    Disease mutation    DNA repair    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Zinc-finger   
SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens)
SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens)
GO:  intracellular    nucleus    ubiquitin ligase complex    DNA binding    ubiquitin-protein ligase activity    zinc ion binding    DNA repair    protein ubiquitination   


CHAIN: C
SWISS-PROT/TREMBL: P38398
   KEYWORD: 3D-structure    Anti-oncogene    Disease mutation    DNA repair    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Zinc-finger   
SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens)
SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens)
GO:  intracellular    nucleus    ubiquitin ligase complex    DNA binding    ubiquitin-protein ligase activity    zinc ion binding    DNA repair    protein ubiquitination   


CHAIN: D
SWISS-PROT/TREMBL: P38398
   KEYWORD: 3D-structure    Anti-oncogene    Disease mutation    DNA repair    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Zinc-finger   
SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens)
SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens)
GO:  intracellular    nucleus    ubiquitin ligase complex    DNA binding    ubiquitin-protein ligase activity    zinc ion binding    DNA repair    protein ubiquitination   


CHAIN: E
SWISS-PROT/TREMBL: P38398
   KEYWORD: 3D-structure    Anti-oncogene    Disease mutation    DNA repair    DNA-binding    Nuclear protein    Phosphorylation    Polymorphism    Repeat    Zinc-finger   
SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens)
SCOP: c.15.1.3 Alpha and beta proteins (a/b)    BRCT domain    BRCT domain    Breast cancer associated protein, BRCA1    Breast cancer associated protein, BRCA1    Human (Homo sapiens)
GO:  intracellular    nucleus    ubiquitin ligase complex    DNA binding    ubiquitin-protein ligase activity    zinc ion binding    DNA repair    protein ubiquitination   
1t2v Image
Image Source: PDB
Homologous structures to 1t2v classified in ArchDB

1l0b A - percentage of sequence identity: 65
1t15 A - percentage of sequence identity: 100