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Information on 1tgs
PDB: 1tgs
Compound: Trypsinogen complex with porcine pancreatic secret
Classification: COMPLEX (PROTEINASE/INHIBITOR)
Entry date in PDB: 1983-01-18
Resolution [Å]: 1.80
R-Factor: 0.186


CHAIN: I
SWISS-PROT/TREMBL: P00998
   KEYWORD: 3D-structure    Serine protease inhibitor   
SCOP: g.68.1.1 Small proteins    Kazal-type serine protease inhibitors    Kazal-type serine protease inhibitors    Ovomucoid domain III-like    Secretory trypsin inhibitor    Pig (Sus scrofa)
GO:  serine-type endopeptidase inhibitor activity   


CHAIN: Z
SWISS-PROT/TREMBL: P00760
   KEYWORD: 3D-structure    Calcium-binding    Digestion    Hydrolase    Pancreas    Serine protease    Signal    Zymogen   
EC: 3.4.21.4
SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Trypsin(ogen)    Cow (Bos taurus)
GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis   
1tgs Image
Image Source: PDB

Stored Loops of 1tgs

Loops in ArchDB40 clusters

1tgs_I_23 - HA => SUBCLASS : 3.1.1
1tgs_I_23 - HA => SUBCLASS : 4.2.1
1tgs_I_30 - EH => SUBCLASS : 0.1.1

Loops in ArchDB95 clusters

1tgs_I_30 - EH => SUBCLASS : 2.1.4
1tgs_I_34 - HE => SUBCLASS : 6.47.1
1tgs_I_23 - HA => SUBCLASS : 3.1.1
1tgs_I_23 - HA => SUBCLASS : 3.1.2

Homologous structures to 1tgs classified in ArchDB

1a0j A - percentage of sequence identity: 73
1cgi I - percentage of sequence identity: 71
1cgj I - percentage of sequence identity: 71
1f7z A - percentage of sequence identity: 74
1fni A - percentage of sequence identity: 81
1h4w A - percentage of sequence identity: 72
1hj8 A - percentage of sequence identity: 66
1hj9 A - percentage of sequence identity: 100
1s83 A - percentage of sequence identity: 82
1trn A - percentage of sequence identity: 75