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Information on 2abl
PDB: 2abl
Compound: abl tyrosine kinase
Classification: TRANSFERASE
Entry date in PDB: 1997-09-04
Resolution [Å]: 2.50
R-Factor: 0.183


CHAIN: -
SWISS-PROT/TREMBL: P00519
   KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Phosphorylation    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase   
EC: 2.7.1.112
SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    Abl tyrosine kinase, SH3 domain    Human (Homo sapiens)
SCOP: d.93.1.1 Alpha and beta proteins (a+b)    SH2-like    SH2 domain    SH2 domain    Abl tyrosine kinase    Human (Homo sapiens)
GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation   
2abl Image
Image Source: PDB

Stored Loops of 2abl

Loops in ArchDB95 clusters

2abl_*_210 - EH => SUBCLASS : 2.1.1
2abl_*_203 - HA => SUBCLASS : 4.2.1
2abl_*_168 - HA => SUBCLASS : 6.3.1

Loops not clustered in ArchDB

2abl_*_126 - AR
2abl_*_135 - AR
2abl_*_147 - EH
2abl_*_84 - HA
2abl_*_106 - HA
2abl_*_118 - HA
2abl_*_180 - HA
2abl_*_189 - HA
2abl_*_153 - HE

Homologous structures to 2abl classified in ArchDB

1ab2 - - percentage of sequence identity: 100
1abo A - percentage of sequence identity: 100
1abo B - percentage of sequence identity: 100
1abq - - percentage of sequence identity: 100
1awo - - percentage of sequence identity: 96
1bbz C - percentage of sequence identity: 100
1bbz E - percentage of sequence identity: 98
1bbz G - percentage of sequence identity: 100
1ju5 C - percentage of sequence identity: 100
1opl A - percentage of sequence identity: 100
1opl B - percentage of sequence identity: 100