PDB: 2hpe Compound: Hiv-2 protease mutant with lys 57 replaced by leu Classification: HYDROLASE(ACID PROTEASE) Entry date in PDB: 1994-10-15 Resolution [Å]: 2.00 R-Factor: 0.150

CHAIN: A SWISS-PROT/TREMBL: P04584    KEYWORD: 3D-structure    AIDS    Aspartyl protease    Endonuclease    Hydrolase    Metal-binding    Nuclease    Polyprotein    RNA-directed DNA polymerase    Transferase    Zinc    Zinc-finger    EC: 2.7.7.49 SCOP: b.50.1.1 All beta proteins    Acid proteases    Acid proteases    Retroviral protease (retropepsin)    Human immunodeficiency virus type 2 (HIV-2) protease    Human immunodeficiency virus type 2 GO:  aspartic-type endopeptidase activity    DNA binding    integrase activity    nucleic acid binding    ribonuclease H activity    RNA binding    RNA-directed DNA polymerase activity    zinc ion binding    DNA integration    DNA recombination    proteolysis and peptidolysis    RNA-dependent DNA replication    CHAIN: B SWISS-PROT/TREMBL: P04584    KEYWORD: 3D-structure    AIDS    Aspartyl protease    Endonuclease    Hydrolase    Metal-binding    Nuclease    Polyprotein    RNA-directed DNA polymerase    Transferase    Zinc    Zinc-finger    EC: 2.7.7.49 SCOP: b.50.1.1 All beta proteins    Acid proteases    Acid proteases    Retroviral protease (retropepsin)    Human immunodeficiency virus type 2 (HIV-2) protease    Human immunodeficiency virus type 2 GO:  aspartic-type endopeptidase activity    DNA binding    integrase activity    nucleic acid binding    ribonuclease H activity    RNA binding    RNA-directed DNA polymerase activity    zinc ion binding    DNA integration    DNA recombination    proteolysis and peptidolysis    RNA-dependent DNA replication

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1ida A - percentage of sequence identity: 98