PDB: 2nac Compound: Nad-dependent formate dehydrogenase (apo form) Classification: OXIDOREDUCTASE(ALDEHYDE(D),NAD+(A)) Entry date in PDB: 1995-01-26 Resolution [Å]: 1.80 R-Factor: 0.146

CHAIN: A SWISS-PROT/TREMBL: P33160    KEYWORD: 3D-structure    NAD    Oxidoreductase    EC: 1.2.1.2 SCOP: c.2.1.4 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Formate/glycerate dehydrogenases, NAD-domain    Formate dehydrogenase    Pseudomonas sp., strain 101 SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    Formate dehydrogenase    Pseudomonas sp., strain 101 SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    Formate dehydrogenase    Pseudomonas sp., strain 101 GO:  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor    L-serine biosynthesis    CHAIN: B SWISS-PROT/TREMBL: P33160    KEYWORD: 3D-structure    NAD    Oxidoreductase    EC: 1.2.1.2 SCOP: c.2.1.4 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Formate/glycerate dehydrogenases, NAD-domain    Formate dehydrogenase    Pseudomonas sp., strain 101 SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    Formate dehydrogenase    Pseudomonas sp., strain 101 SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    Formate dehydrogenase    Pseudomonas sp., strain 101 GO:  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor    L-serine biosynthesis

Image Source: PDB

Loops in ArchDB40 clusters

2nac_A_366 - HA => SUBCLASS : 2.1.1
2nac_A_236 - EH => SUBCLASS : 2.1.6
2nac_A_236 - EH => SUBCLASS : 2.1.18
2nac_A_193 - EH => SUBCLASS : 3.2.1
2nac_A_216 - EH => SUBCLASS : 5.3.1
2nac_A_216 - EH => SUBCLASS : 5.3.2
2nac_A_277 - EH => SUBCLASS : 8.14.1
2nac_A_250 - EH => SUBCLASS : 13.1.1
2nac_A_147 - HH => SUBCLASS : 1.3.1

Loops in ArchDB95 clusters

2nac_A_236 - EH => SUBCLASS : 2.1.6
2nac_A_193 - EH => SUBCLASS : 3.5.1
2nac_A_216 - EH => SUBCLASS : 5.4.1
2nac_A_216 - EH => SUBCLASS : 5.31.1
2nac_A_277 - EH => SUBCLASS : 8.17.1
2nac_A_250 - EH => SUBCLASS : 13.3.1
2nac_A_147 - HH => SUBCLASS : 1.3.1
2nac_A_129 - HE => SUBCLASS : 1.1.1
2nac_A_60 - HE => SUBCLASS : 1.1.1
2nac_A_129 - HE => SUBCLASS : 2.1.1
2nac_A_227 - HE => SUBCLASS : 2.1.3
2nac_A_129 - HE => SUBCLASS : 2.1.3
2nac_A_201 - HE => SUBCLASS : 2.1.18
2nac_A_201 - HE => SUBCLASS : 2.1.20
2nac_A_241 - HE => SUBCLASS : 2.2.9
2nac_A_241 - HE => SUBCLASS : 2.2.10
2nac_A_290 - HE => SUBCLASS : 2.4.1
2nac_A_201 - HE => SUBCLASS : 2.5.6
2nac_A_267 - HE => SUBCLASS : 4.59.1
2nac_A_105 - HE => SUBCLASS : 5.9.1
2nac_A_366 - HA => SUBCLASS : 2.1.1

Loops in ArchDB-EC clusters

2nac_A_147 - HH => SUBCLASS : 1.3.1

Loops not clustered in ArchDB

2nac_A_2 - EH
2nac_A_302 - EH
2nac_A_138 - EH
2nac_A_116 - EH
2nac_A_92 - EH
2nac_A_69 - EH
2nac_A_366 - HA
2nac_A_82 - HE
2nac_A_179 - HE
2nac_A_338 - HE
2nac_A_165 - HH

2nac A - percentage of sequence identity: 100
2nac B - percentage of sequence identity: 100
2nad A - percentage of sequence identity: 100
2nad B - percentage of sequence identity: 100