PDB: 2pgd Compound: 6-phosphogluconate dehydrogenase (6-pgdh) Classification: OXIDOREDUCTASE (CHOH(D)-NADP+(A)) Entry date in PDB: 1995-02-27 Resolution [Å]: 2.00 R-Factor: 0.198

CHAIN: - SWISS-PROT/TREMBL: P00349    KEYWORD: 3D-structure    NADP    Oxidoreductase    Pentose shunt    EC: 1.1.1.44 SCOP: a.100.1.1 All alpha proteins    6-phosphogluconate dehydrogenase C-terminal domain-like    6-phosphogluconate dehydrogenase C-terminal domain-like    Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain    6-phosphogluconate dehydrogenase (6PGD)    Sheep (Ovis orientalis aries) SCOP: c.2.1.6 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    6-phosphogluconate dehydrogenase-like, N-terminal domain    6-phosphogluconate dehydrogenase    Sheep (Ovis orientalis aries) GO:  NADP binding    phosphogluconate dehydrogenase (decarboxylating) activity    pentose-phosphate shunt    pentose-phosphate shunt, oxidative branch

Image Source: PDB

Loops in ArchDB40 clusters

2pgd_*_105 - HE => SUBCLASS : 1.1.1
2pgd_*_12 - HE => SUBCLASS : 2.1.1
2pgd_*_174 - EH => SUBCLASS : 1.2.13
2pgd_*_28 - EH => SUBCLASS : 2.1.1
2pgd_*_52 - EH => SUBCLASS : 2.1.2
2pgd_*_5 - EH => SUBCLASS : 3.32.1
2pgd_*_392 - HH => SUBCLASS : 3.1.4
2pgd_*_178 - HH => SUBCLASS : 3.3.2
2pgd_*_262 - HH => SUBCLASS : 4.7.1
2pgd_*_212 - HH => SUBCLASS : 5.4.1

Loops in ArchDB95 clusters

2pgd_*_28 - EH => SUBCLASS : 2.1.1
2pgd_*_52 - EH => SUBCLASS : 2.1.3
2pgd_*_5 - EH => SUBCLASS : 3.39.1
2pgd_*_178 - HH => SUBCLASS : 3.1.2
2pgd_*_392 - HH => SUBCLASS : 3.1.8
2pgd_*_178 - HH => SUBCLASS : 3.2.1
2pgd_*_262 - HH => SUBCLASS : 4.3.1
2pgd_*_212 - HH => SUBCLASS : 5.3.1
2pgd_*_105 - HE => SUBCLASS : 1.1.1
2pgd_*_12 - HE => SUBCLASS : 2.1.1
2pgd_*_78 - HE => SUBCLASS : 5.5.1

Loops in ArchDB-EC clusters

2pgd_*_212 - HH => SUBCLASS : 5.5.3

Loops not clustered in ArchDB

2pgd_*_69 - EH
2pgd_*_96 - EH
2pgd_*_121 - EH
2pgd_*_139 - EH
2pgd_*_149 - HE
2pgd_*_130 - HE
2pgd_*_57 - HE
2pgd_*_36 - HE
2pgd_*_230 - HH
2pgd_*_278 - HH
2pgd_*_293 - HH
2pgd_*_315 - HH
2pgd_*_354 - HH
2pgd_*_371 - HH
2pgd_*_420 - HH

1pgn - - percentage of sequence identity: 100
1pgo - - percentage of sequence identity: 100
1pgp - - percentage of sequence identity: 100
1pgq - - percentage of sequence identity: 100