PDB: 2pka Compound: Kallikrein a Classification: SERINE PROTEINASE Entry date in PDB: 1984-07-19 Resolution [Å]: 2.05 R-Factor: 0.220

CHAIN: A SWISS-PROT/TREMBL: P00752    KEYWORD: 3D-structure    Glycoprotein    Hydrolase    Pancreas    Serine protease    Zymogen    EC: 3.4.21.35 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Kallikrein A    Pig (Sus scrofa) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P00752    KEYWORD: 3D-structure    Glycoprotein    Hydrolase    Pancreas    Serine protease    Zymogen    EC: 3.4.21.35 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Kallikrein A    Pig (Sus scrofa) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis    CHAIN: X SWISS-PROT/TREMBL: P00752    KEYWORD: 3D-structure    Glycoprotein    Hydrolase    Pancreas    Serine protease    Zymogen    EC: 3.4.21.35 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Kallikrein A    Pig (Sus scrofa) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis    CHAIN: Y SWISS-PROT/TREMBL: P00752    KEYWORD: 3D-structure    Glycoprotein    Hydrolase    Pancreas    Serine protease    Zymogen    EC: 3.4.21.35 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Kallikrein A    Pig (Sus scrofa) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB95 clusters

2pka_B_226 - EH => SUBCLASS : 0.1.2
2pka_B_156 - EH => SUBCLASS : 1.1.5
2pka_A_51 - AR => SUBCLASS : 7.7.1
2pka_B_180 - AR => SUBCLASS : 16.1.1
2pka_B_198 - HA => SUBCLASS : 2.1.1
2pka_A_39 - HA => SUBCLASS : 2.2.15
2pka_A_30 - HA => SUBCLASS : 2.5.5
2pka_A_64 - HA => SUBCLASS : 12.3.1

Loops in ArchDB-EC clusters

2pka_B_165 - HE => SUBCLASS : 8.4.1

Loops not clustered in ArchDB

2pka_A_51 - AR
2pka_B_180 - AR
2pka_B_135 - HA
2pka_A_39 - HA
2pka_A_30 - HA
2pka_B_208 - HA
2pka_B_198 - HA
2pka_B_135 - HA
2pka_B_208 - HA
2pka_A_64 - HA

1gvz A - percentage of sequence identity: 66
1hia B - percentage of sequence identity: 100
1hia Y - percentage of sequence identity: 100
1sgf A - percentage of sequence identity: 60
1sgf G - percentage of sequence identity: 64
1sgf X - percentage of sequence identity: 60
1sgf Z - percentage of sequence identity: 64
1spj A - percentage of sequence identity: 65
2kai B - percentage of sequence identity: 100
2pka B - percentage of sequence identity: 100
2pka Y - percentage of sequence identity: 100