PDB: 3lck Compound: proto-oncogene tyrosine-protein kinase Classification: TYROSINE-PROTEIN KINASE Entry date in PDB: 1997-12-03 Resolution [Å]: 1.70 R-Factor: 0.178

CHAIN: - SWISS-PROT/TREMBL: P06239    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Disease mutation    Lipoprotein    Myristate    Palmitate    Phosphorylation    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Lymphocyte kinase (lck)    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation

Image Source: PDB

Loops in ArchDB-KI clusters

3lck_*_378 - AR => SUBCLASS : 5.1.1
3lck_*_360 - AR => SUBCLASS : 8.1.1
3lck_*_313 - EH => SUBCLASS : 6.3.1
3lck_*_257 - HA => SUBCLASS : 3.3.1
3lck_*_370 - HA => SUBCLASS : 4.1.1
3lck_*_282 - HE => SUBCLASS : 8.1.1
3lck_*_467 - HH => SUBCLASS : 9.1.3
3lck_*_419 - HH => SUBCLASS : 10.1.1

Loops not clustered in ArchDB-KI

3lck_*_268 - EH
3lck_*_387 - EH
3lck_*_303 - HA
3lck_*_338 - HE
3lck_*_331 - HH
3lck_*_324 - HH
3lck_*_446 - HH
3lck_*_409 - HH

1fmk - - percentage of sequence identity: 67
1qcf A - percentage of sequence identity: 76
1qpc A - percentage of sequence identity: 100