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Information on 4nos
PDB: 4nos
Compound: inducible nitric oxide synthase
Classification: OXIDOREDUCTASE
Entry date in PDB: 2000-02-04
Resolution [Å]: 2.25
R-Factor: 0.199


CHAIN: A
SWISS-PROT/TREMBL: P35228
   KEYWORD: 3D-structure    Alternative splicing    Calcium-binding    Calmodulin-binding    FAD    FMN    Heme    Metal-binding    Multigene family    NADP    Oxidoreductase    Phosphorylation    Zinc   
EC: 1.14.13.39
SCOP: d.174.1.1 Alpha and beta proteins (a+b)    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Human (Homo sapiens)
GO:  electron transporter activity    FMN binding    nitric-oxide synthase activity    oxidoreductase activity    electron transport    nitric oxide biosynthesis   


CHAIN: B
SWISS-PROT/TREMBL: P35228
   KEYWORD: 3D-structure    Alternative splicing    Calcium-binding    Calmodulin-binding    FAD    FMN    Heme    Metal-binding    Multigene family    NADP    Oxidoreductase    Phosphorylation    Zinc   
EC: 1.14.13.39
SCOP: d.174.1.1 Alpha and beta proteins (a+b)    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Human (Homo sapiens)
GO:  electron transporter activity    FMN binding    nitric-oxide synthase activity    oxidoreductase activity    electron transport    nitric oxide biosynthesis   


CHAIN: C
SWISS-PROT/TREMBL: P35228
   KEYWORD: 3D-structure    Alternative splicing    Calcium-binding    Calmodulin-binding    FAD    FMN    Heme    Metal-binding    Multigene family    NADP    Oxidoreductase    Phosphorylation    Zinc   
EC: 1.14.13.39
SCOP: d.174.1.1 Alpha and beta proteins (a+b)    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Human (Homo sapiens)
GO:  electron transporter activity    FMN binding    nitric-oxide synthase activity    oxidoreductase activity    electron transport    nitric oxide biosynthesis   


CHAIN: D
SWISS-PROT/TREMBL: P35228
   KEYWORD: 3D-structure    Alternative splicing    Calcium-binding    Calmodulin-binding    FAD    FMN    Heme    Metal-binding    Multigene family    NADP    Oxidoreductase    Phosphorylation    Zinc   
EC: 1.14.13.39
SCOP: d.174.1.1 Alpha and beta proteins (a+b)    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Nitric oxide (NO) synthase oxygenase domain    Human (Homo sapiens)
GO:  electron transporter activity    FMN binding    nitric-oxide synthase activity    oxidoreductase activity    electron transport    nitric oxide biosynthesis   
4nos Image
Image Source: PDB

Stored Loops of 4nos

Loops in ArchDB95 clusters

4nos_A_433 - EH => SUBCLASS : 1.1.2
4nos_A_433 - EH => SUBCLASS : 1.1.11
4nos_A_488 - EH => SUBCLASS : 4.10.1
4nos_A_210 - EH => SUBCLASS : 6.14.1
4nos_A_258 - AR => SUBCLASS : 9.13.1
4nos_A_159 - HH => SUBCLASS : 6.55.1
4nos_A_392 - HH => SUBCLASS : 10.5.1
4nos_A_410 - HE => SUBCLASS : 2.1.1
4nos_A_183 - HE => SUBCLASS : 11.2.1
4nos_A_284 - HE => SUBCLASS : 13.1.1
4nos_A_461 - HE => SUBCLASS : 23.1.1
4nos_A_269 - HA => SUBCLASS : 3.1.1
4nos_A_85 - HA => SUBCLASS : 4.1.1
4nos_A_307 - HA => SUBCLASS : 5.32.1
4nos_A_328 - HA => SUBCLASS : 14.3.1

Loops in ArchDB-EC clusters

4nos_A_392 - HH => SUBCLASS : 10.4.1

Loops not clustered in ArchDB

4nos_A_369 - AR
4nos_A_362 - AR
4nos_A_369 - AR
4nos_A_243 - AR
4nos_A_258 - AR
4nos_A_317 - AR
4nos_A_345 - AR
4nos_A_351 - AR
4nos_A_362 - AR
4nos_A_351 - AR
4nos_A_345 - AR
4nos_A_317 - AR
4nos_A_243 - AR
4nos_A_277 - EH
4nos_A_373 - EH
4nos_A_95 - EH
4nos_A_307 - HA
4nos_A_269 - HA
4nos_A_356 - HA
4nos_A_356 - HA
4nos_A_328 - HA
4nos_A_85 - HA
4nos_A_220 - HE
4nos_A_136 - HH
4nos_A_436 - HH
4nos_A_375 - HH

Homologous structures to 4nos classified in ArchDB

1dd7 A - percentage of sequence identity: 88
1df1 A - percentage of sequence identity: 86
1df1 B - percentage of sequence identity: 86
1dwv A - percentage of sequence identity: 87
1dwv B - percentage of sequence identity: 87
1dww A - percentage of sequence identity: 87
1dww B - percentage of sequence identity: 87
1dwx A - percentage of sequence identity: 87
1dwx B - percentage of sequence identity: 87
1jwj A - percentage of sequence identity: 86
1jwj B - percentage of sequence identity: 86
1jwk A - percentage of sequence identity: 86
1jwk B - percentage of sequence identity: 86
1k2r A - percentage of sequence identity: 65
1k2r B - percentage of sequence identity: 65
1k2s A - percentage of sequence identity: 65
1k2s B - percentage of sequence identity: 65
1k2t A - percentage of sequence identity: 65
1k2t B - percentage of sequence identity: 65
1k2u A - percentage of sequence identity: 65
1k2u B - percentage of sequence identity: 65
1lzx A - percentage of sequence identity: 65
1lzx B - percentage of sequence identity: 65
1lzz A - percentage of sequence identity: 65
1lzz B - percentage of sequence identity: 65
1m00 A - percentage of sequence identity: 65
1m00 B - percentage of sequence identity: 65
1m8d A - percentage of sequence identity: 86
1m8d B - percentage of sequence identity: 86
1m8e A - percentage of sequence identity: 86
1m8e B - percentage of sequence identity: 86
1m8h A - percentage of sequence identity: 86
1m8h B - percentage of sequence identity: 86
1m8i A - percentage of sequence identity: 86
1m8i B - percentage of sequence identity: 86
1m9j A - percentage of sequence identity: 60
1m9j B - percentage of sequence identity: 60
1m9k A - percentage of sequence identity: 60
1m9k B - percentage of sequence identity: 60
1m9m A - percentage of sequence identity: 60
1m9m B - percentage of sequence identity: 60
1m9q A - percentage of sequence identity: 60
1m9q B - percentage of sequence identity: 60
1m9r A - percentage of sequence identity: 60
1m9r B - percentage of sequence identity: 60
1m9t A - percentage of sequence identity: 86
1m9t B - percentage of sequence identity: 86
1mmv A - percentage of sequence identity: 65
1mmv B - percentage of sequence identity: 65
1mmw A - percentage of sequence identity: 65
1mmw B - percentage of sequence identity: 65
1n2n A - percentage of sequence identity: 87
1n2n B - percentage of sequence identity: 87
1noc A - percentage of sequence identity: 88
1nod A - percentage of sequence identity: 86
1nod B - percentage of sequence identity: 86
1nos - - percentage of sequence identity: 88
1nsi A - percentage of sequence identity: 99
1nsi B - percentage of sequence identity: 99
1nsi C - percentage of sequence identity: 99
1nsi D - percentage of sequence identity: 99
1om4 A - percentage of sequence identity: 65
1om4 B - percentage of sequence identity: 65
1om5 A - percentage of sequence identity: 65
1om5 B - percentage of sequence identity: 65
1p6h A - percentage of sequence identity: 65
1p6h B - percentage of sequence identity: 65
1p6i A - percentage of sequence identity: 65
1p6i B - percentage of sequence identity: 65
1p6j A - percentage of sequence identity: 65
1p6j B - percentage of sequence identity: 65
1p6k A - percentage of sequence identity: 65
1p6k B - percentage of sequence identity: 65
1q2o A - percentage of sequence identity: 60
1q2o B - percentage of sequence identity: 60
1qom A - percentage of sequence identity: 86
1qom B - percentage of sequence identity: 86
1qw4 A - percentage of sequence identity: 87
1qw4 B - percentage of sequence identity: 87
1qw5 A - percentage of sequence identity: 87
1qw5 B - percentage of sequence identity: 87
1qw6 A - percentage of sequence identity: 65
1qwc A - percentage of sequence identity: 65
1r35 A - percentage of sequence identity: 86
1r35 B - percentage of sequence identity: 86
1rs6 A - percentage of sequence identity: 65
1rs6 B - percentage of sequence identity: 65
1rs7 A - percentage of sequence identity: 65
1rs7 B - percentage of sequence identity: 65
1vaf A - percentage of sequence identity: 87
1vaf B - percentage of sequence identity: 87
1vag A - percentage of sequence identity: 65
1zvi A - percentage of sequence identity: 65
1zvl A - percentage of sequence identity: 65
1zvl B - percentage of sequence identity: 65
1zzq A - percentage of sequence identity: 65
1zzq B - percentage of sequence identity: 65
1zzr A - percentage of sequence identity: 65
1zzr B - percentage of sequence identity: 65
1zzs A - percentage of sequence identity: 60
1zzs B - percentage of sequence identity: 60
1zzt A - percentage of sequence identity: 60
1zzt B - percentage of sequence identity: 60
1zzu A - percentage of sequence identity: 65
1zzu B - percentage of sequence identity: 65
2bhj A - percentage of sequence identity: 86
2nod A - percentage of sequence identity: 86
2nod B - percentage of sequence identity: 86
2nos - - percentage of sequence identity: 88
2nsi A - percentage of sequence identity: 99
2nsi B - percentage of sequence identity: 99
2nsi C - percentage of sequence identity: 99
2nsi D - percentage of sequence identity: 99
3nod A - percentage of sequence identity: 86
3nod B - percentage of sequence identity: 86
3nos A - percentage of sequence identity: 60
3nos B - percentage of sequence identity: 60
4nos A - percentage of sequence identity: 100
4nos B - percentage of sequence identity: 100
4nos C - percentage of sequence identity: 100
4nos D - percentage of sequence identity: 100