PDB: 7req Compound: methylmalonyl-coa mutase Classification: ISOMERASE Entry date in PDB: 1998-09-16 Resolution [Å]: 2.20 R-Factor: 0.195

CHAIN: A SWISS-PROT/TREMBL: P11653    KEYWORD: 3D-structure    Cobalt    Isomerase    Vitamin B12    EC: 5.4.99.2 SCOP: c.1.19.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Cobalamin (vitamin B12)-dependent enzymes    Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain    Methylmalonyl-CoA mutase alpha subunit, domain 1    Propionibacterium freudenreichii, subsp. shermanii SCOP: c.23.6.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Cobalamin (vitamin B12)-binding domain    Cobalamin (vitamin B12)-binding domain    Methylmalonyl-CoA mutase alpha subunit, C-terminal domain    Propionibacterium freudenreichii, subsp. shermanii GO:  cobalt ion binding    isomerase activity    methylmalonyl-CoA mutase activity    metabolism    CHAIN: B SWISS-PROT/TREMBL: P11652    KEYWORD: 3D-structure    Cobalt    Isomerase    Vitamin B12    EC: 5.4.99.2 SCOP: c.1.19.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Cobalamin (vitamin B12)-dependent enzymes    Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain    Methylmalonyl-CoA mutase beta subunit, domain 1    Propionibacterium freudenreichii, subsp. shermanii SCOP: c.23.6.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Cobalamin (vitamin B12)-binding domain    Cobalamin (vitamin B12)-binding domain    Methylmalonyl-CoA mutase beta subunit, C-terminal domain    Propionibacterium freudenreichii, subsp. shermanii GO:  cobalt ion binding    methylmalonyl-CoA mutase activity    metabolism    propionate fermentation    CHAIN: C SWISS-PROT/TREMBL: P11653    KEYWORD: 3D-structure    Cobalt    Isomerase    Vitamin B12    EC: 5.4.99.2 SCOP: c.1.19.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Cobalamin (vitamin B12)-dependent enzymes    Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain    Methylmalonyl-CoA mutase alpha subunit, domain 1    Propionibacterium freudenreichii, subsp. shermanii SCOP: c.23.6.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Cobalamin (vitamin B12)-binding domain    Cobalamin (vitamin B12)-binding domain    Methylmalonyl-CoA mutase alpha subunit, C-terminal domain    Propionibacterium freudenreichii, subsp. shermanii GO:  cobalt ion binding    isomerase activity    methylmalonyl-CoA mutase activity    metabolism    CHAIN: D SWISS-PROT/TREMBL: P11652    KEYWORD: 3D-structure    Cobalt    Isomerase    Vitamin B12    EC: 5.4.99.2 SCOP: c.1.19.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Cobalamin (vitamin B12)-dependent enzymes    Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain    Methylmalonyl-CoA mutase beta subunit, domain 1    Propionibacterium freudenreichii, subsp. shermanii SCOP: c.23.6.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Cobalamin (vitamin B12)-binding domain    Cobalamin (vitamin B12)-binding domain    Methylmalonyl-CoA mutase beta subunit, C-terminal domain    Propionibacterium freudenreichii, subsp. shermanii GO:  cobalt ion binding    methylmalonyl-CoA mutase activity    metabolism    propionate fermentation

Image Source: PDB

Loops in ArchDB40 clusters

7req_A_38 - HA => SUBCLASS : 3.1.1
7req_B_64 - HA => SUBCLASS : 3.1.1
7req_B_232 - EH => SUBCLASS : 0.1.16
7req_A_238 - EH => SUBCLASS : 0.1.69
7req_A_113 - EH => SUBCLASS : 1.1.6
7req_A_113 - EH => SUBCLASS : 1.1.12
7req_A_284 - EH => SUBCLASS : 2.1.7
7req_B_280 - EH => SUBCLASS : 2.1.7
7req_B_514 - EH => SUBCLASS : 2.5.1
7req_B_163 - EH => SUBCLASS : 3.1.7
7req_B_163 - EH => SUBCLASS : 3.9.6
7req_A_651 - EH => SUBCLASS : 3.15.1
7req_A_701 - EH => SUBCLASS : 4.23.2
7req_B_615 - EH => SUBCLASS : 5.5.3
7req_A_235 - AR => SUBCLASS : 1.1.7
7req_B_429 - HH => SUBCLASS : 1.1.16
7req_A_433 - HH => SUBCLASS : 1.3.1
7req_A_485 - HH => SUBCLASS : 2.1.5
7req_A_407 - HH => SUBCLASS : 2.6.1
7req_B_403 - HH => SUBCLASS : 2.6.1
7req_A_252 - HH => SUBCLASS : 3.1.1
7req_A_531 - HH => SUBCLASS : 3.3.1
7req_A_243 - HH => SUBCLASS : 3.3.1
7req_B_239 - HH => SUBCLASS : 3.3.1
7req_B_248 - HH => SUBCLASS : 3.3.1

Loops in ArchDB95 clusters

7req_B_232 - EH => SUBCLASS : 0.1.15
7req_A_238 - EH => SUBCLASS : 0.1.32
7req_A_113 - EH => SUBCLASS : 1.1.3
7req_A_113 - EH => SUBCLASS : 1.1.55
7req_A_284 - EH => SUBCLASS : 2.1.12
7req_B_280 - EH => SUBCLASS : 2.1.12
7req_B_369 - EH => SUBCLASS : 2.1.33
7req_B_163 - EH => SUBCLASS : 3.2.5
7req_B_163 - EH => SUBCLASS : 3.9.7
7req_B_514 - EH => SUBCLASS : 3.41.1
7req_B_108 - EH => SUBCLASS : 4.6.3
7req_B_615 - EH => SUBCLASS : 5.20.1
7req_A_627 - EH => SUBCLASS : 6.20.1
7req_A_235 - AR => SUBCLASS : 1.2.5
7req_B_429 - HH => SUBCLASS : 1.1.24
7req_A_433 - HH => SUBCLASS : 1.3.1
7req_A_485 - HH => SUBCLASS : 2.1.1
7req_B_403 - HH => SUBCLASS : 2.6.1
7req_A_407 - HH => SUBCLASS : 2.6.1
7req_A_243 - HH => SUBCLASS : 3.1.1
7req_A_252 - HH => SUBCLASS : 3.1.1
7req_B_248 - HH => SUBCLASS : 3.1.1
7req_A_531 - HH => SUBCLASS : 3.2.1
7req_A_243 - HH => SUBCLASS : 3.2.1
7req_B_239 - HH => SUBCLASS : 3.2.1
7req_B_248 - HH => SUBCLASS : 3.2.1
7req_B_606 - HE => SUBCLASS : 2.3.8
7req_B_550 - HE => SUBCLASS : 3.1.1
7req_B_571 - HE => SUBCLASS : 3.1.1
7req_B_571 - HE => SUBCLASS : 3.1.4
7req_B_521 - HE => SUBCLASS : 5.10.1
7req_A_38 - HA => SUBCLASS : 3.1.1
7req_B_64 - HA => SUBCLASS : 3.1.1

Loops not clustered in ArchDB

7req_A_45 - AR
7req_A_85 - AR
7req_B_71 - AR
7req_B_357 - AR
7req_B_195 - EH
7req_B_322 - EH
7req_B_476 - EH
7req_B_544 - EH
7req_B_564 - EH
7req_B_592 - EH
7req_B_135 - EH
7req_A_681 - EH
7req_A_89 - EH
7req_A_163 - EH
7req_A_194 - EH
7req_A_327 - EH
7req_A_362 - EH
7req_A_599 - EH
7req_B_55 - HE
7req_B_118 - HE
7req_B_150 - HE
7req_B_172 - HE
7req_B_217 - HE
7req_B_273 - HE
7req_B_290 - HE
7req_B_338 - HE
7req_B_437 - HE
7req_B_495 - HE
7req_A_693 - HE
7req_A_661 - HE
7req_A_637 - HE
7req_A_21 - HE
7req_A_95 - HE
7req_A_146 - HE
7req_A_171 - HE
7req_A_214 - HE
7req_A_277 - HE
7req_A_294 - HE
7req_A_343 - HE
7req_A_578 - HE
7req_A_612 - HE
7req_B_201 - HH
7req_B_32 - HH
7req_A_569 - HH
7req_A_545 - HH
7req_A_505 - HH
7req_A_441 - HH
7req_A_377 - HH
7req_A_201 - HH
7req_A_119 - HH
7req_B_374 - HH

1e1c A - percentage of sequence identity: 99
1e1c C - percentage of sequence identity: 99
1req A - percentage of sequence identity: 100
1req C - percentage of sequence identity: 100
2req A - percentage of sequence identity: 100
2req C - percentage of sequence identity: 100
3req A - percentage of sequence identity: 100
4req A - percentage of sequence identity: 100
4req C - percentage of sequence identity: 100
5req A - percentage of sequence identity: 99
5req C - percentage of sequence identity: 99
6req A - percentage of sequence identity: 100
6req C - percentage of sequence identity: 100
7req A - percentage of sequence identity: 100
7req C - percentage of sequence identity: 100