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Information on SUBCLASS 1.1.4
Subclass Accession number: 2633
Subclass: 1.1.4 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 86

Average sequence ID (%) : 8.6 +/- 13.0
Average RMSD (Å) : 0.470 +/- 0.195

Consensus geometry
d (Å): 7 delta (°): 0-45 theta (°): 45-90 rho (°): 180-225
Consensus Sequence: XhXXX
(φψ)-conformation: bbpaa
Pattern: xx[acfgilmpvwy][adegknqrst]x[adegknqrst]xx
Conservation:-1.000-0.7850.7560.776-1.1501.465-0.830-0.232
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
16pk_*_18816pk   -188194.AAGYLME.EE-HHHH.bxxaaaa
1aln_*_321aln   -3238.LLTGEQV.EE-HHHH.bbxaaaa
1avs_A_361avs   A3642.DISTKEL.EE-HHHH.bxxaaaa
1b8z_A_781b8z   A7986FKPGKALKEEE-HHHHbbxxaaaa
1bd0_A_3381bd0   A338345EVISIDDVEEE-HHHHbbbbaaaa
1be4_A_341be4   A4148MRASEDLLEE--HHHHbxxxaaaa
1bup_A_1101bup   A112119KSFYPEEVEEE-HHHHbbbxaaaa
1cbg_*_4741cbg   -475482RHPKLSAHEEE-HHHHxbpxaaaa
1coz_A_301coz   A3441AISTDEFNEEE-HHHHxbpxaaaa
1cpo_*_1471cpo   -147153.HFDYADM.EE-HHHH.bbbaaaa
1d4o_A_241d4o   A2734ITPGYGLCEEE-HHHHbbxbaaaa
1dbt_A_311dbt   A3239VKVGMELFEEE-HHHHbbbbaaaa
1dcs_*_2221dcs   -224231VFCGAIATEEE-HHHHbbxbaaaa
1dvi_A_2251dvi   A225231.NMDFDNF.EE-HHHH.bbxaaaa
1dzf_A_871dzf   A8793.SVGVKTM.EE-HHHH.bxxaaaa
1e3m_B_4981e3m   B500507RYIIPELKEE--HHHHbbbbaaaa
1e4m_M_4821e4m   M486493RDLKKSGQEEE-HHHHbbpxaaaa
1f1e_A_1341f1e   A134140.TVQGEDV.EE-HHHH.bxbaaaa
1gef_A_551gef   A5562LYVGKRDMEEE-HHHHbxbpaaaa
1ggz_A_261ggz   A2632.CITTREL.EE-HHHH.bbxaaaa
1ggz_A_991ggz   A99105.FVSAAEL.EE-HHHH.bxxaaaa
1gnx_A_4571gnx   A458465RIPKASAREEE-HHHHbbpxaaaa
1gs4_A_7681gs4   A768775LVFNEYRMEEE-HHHHbxxbaaaa
1gsa_*_2411gsa   -245252RPLTESDWEE--HHHHbpxxaaaa
1gyt_A_2181gyt   A221228RVIGEQQMEEE-HHHHbbxxaaaa
1h49_A_4851h49   A486493RYMKESAKEEE-HHHHxbpxaaaa
1hc7_A_371hc7   A3744IVVRPYGYEEE-HHHHbbxxaaaa
1htr_B_3011htr   B302309WILGDVFLEEE-HHHHbbxbaaaa
1ie9_A_2941ie9   A294300.KYRVSDV.EE-HHHH.bbbaaaa
1iq0_A_4551iq0   A455462IDFRYQEAEEE-HHHHbbxbaaaa
1j79_A_1941j79   A196203ATITPQHLEEE-HHHHbbbxaaaa
1jfl_A_2101jfl   A210216.LIDPMDV.EE-HHHH.bbbaaaa
1jk7_A_2251jk7   A225232FTFGAEVVEEE-HHHHbbbbaaaa
1jmm_A_5261jmm   A526533KFLKASAVEEE-HHHHbxbpaaaa
1jp4_A_451jp4   A4552DLQTKADREEE-HHHHbbbbaaaa
1jvn_A_3431jvn   A343349.KIPALEV.EE-HHHH.xbxaaaa
1k6k_A_241k6k   A2430.FMTVEHL.EE-HHHH.bbbaaaa
1k6k_A_791k6k   A7985.QPTLSFQ.EE-HHHH.bxxaaaa
1kek_A_1801kek   A184191EVLDYADMEEE-HHHHbbxxaaaa
1kfu_L_6561kfu   L656662.IIDFDNF.EE-HHHH.bbxaaaa
1kic_A_2051kic   A206213IMFSLDSTEEE-HHHHbbxxaaaa
1ko7_A_501ko7   A5158QLLGTTELEEE-HHHHbbbbaaaa
1kyz_A_1021kyz   A106113YGLATVAKEEE-HHHHbbxxaaaa
1lam_*_1981lam   -201208FIRPKSWIEEE-HHHHbxxxaaaa
1ly1_A_291ly1   A3037YNINRDDYEEE-HHHHbxbbaaaa
1m2o_A_6611m2o   A664671IYHGEQIAEEE-HHHHbbbxaaaa
1mr8_A_651mr8   A6571.AVNFQEF.EE-HHHH.bbxaaaa
1mul_A_741mul   A7986FVSGKALKEEE-HHHHbbxxaaaa
1mum_A_421mum   A4249IYLSGGGVEEE-HHHHbbbxaaaa
1mxr_A_1801mxr   A182189VTVSLRELEEE-HHHHbxbbaaaa
1n40_A_3041n40   A305312VLVLLEGAEEE-HHHHbbxxaaaa
1n7z_A_1871n7z   A192199FEIPPDVSEEE-HHHHbbbxaaaa
1o58_A_2281o58   A230237ITVEDEEAEEE-HHHHbxbxaaaa
1ogs_A_4101ogs   A411418FYKQPMFYEEE-HHHHbbxxaaaa
1oim_A_4251oim   A426433RIVKDSGYEEE-HHHHxbpxaaaa
1on2_A_591on2   A6067LVLTSKGKEEE-HHHHxbxxaaaa
1orf_A_2261orf   A229236ILLSKKHLEE--HHHHxxxxaaaa
1otj_A_1501otj   A151158AEHDFRKSEEE-HHHHbxbbaaaa
1owf_A_761owf   A8188FRPGQKLKEEE-HHHHbbpxaaaa
1p71_A_741p71   A7986FSAGKLFREEE-HHHHbbxxaaaa
1pfv_A_3701pfv   A370377IDLNLEDFEEE-HHHHbbbxaaaa
1pj5_A_6831pj5   A683690IAAGRAAFEEE-HHHHbxbbaaaa
1q8f_A_1841q8f   A185192VMMGLDLTEEE-HHHHbbxxaaaa
1q8f_A_1961q8f   A196202.VCTPDVI.EE-HHHH.pxxaaaa
1qnx_A_781qnx   A7884.VWNDELA.EE-HHHH.bxbaaaa
1qpo_A_1691qpo   A169176ALIKDNHVEEE-HHHHxbxbaaaa
1qus_A_3231qus   A326333WYGLPNFYEEE-HHHHbxxbaaaa
1qv0_A_1291qv0   A129135.TITLDEW.EE-HHHH.bbxaaaa
1qwi_A_321qwi   A3239QPYGFNTREEE-HHHHxwbbaaaa
1qyc_A_2401qyc   A242249AYVPEEEVEEE-HHHHbbbxaaaa
1qyi_A_2631qyi   A263269.IATASDV.EE-HHHH.bxbaaaa
1rhs_*_1611rhs   -161167.LKTYEQV.EE-HHHH.bbxaaaa
1s3j_A_931s3j   A95102LSLTDEGDEEE-HHHHbbxxaaaa
1s6c_A_1891s6c   A189195.IVTLDEF.EE-HHHH.bbxaaaa
1sbp_*_2791sbp   -279286KLFTIDEVEEE-HHHHxbbbaaaa
1so2_A_10571so2   A10571063.IFCQLMH.EE-HHHH.bbbaaaa
1st0_A_1481st0   A151158IRETGDDYEEE-HHHHbbxxaaaa
1ubl_L_4921ubl   L497504QLVVPSTWEEE-HHHHbbbbaaaa
1ug6_A_4121ug6   A413420RIPKRSALEEEBHHHHbbxxaaaa
1v39_*_2211v39   -222229TRVTKSDAEEE-HHHHbxbbaaaa
1viu_A_591viu   A6471RQFRVATWEEE-HHHHbbxbaaaa
2hlc_A_1562hlc   A161168LVIDNDRCEEE-HHHHxxbxaaaa
2mas_A_1862mas   A187194TMVGLDLTEEE-HHHHbxxxaaaa
2prd_*_1502prd   -154161GWRDRKAAEEE-HHHHebbxaaaa
2sak_*_542sak   -5460.TLTKEKI.EE-HHHH.xxbaaaa
3pvi_A_1083pvi   A113120YRLEPKDLEEE-HHHHbbbxaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1avs_A_361avs   A     CACALCIUM ION D - 36
1avs_A_361avs   A     CACALCIUM ION I - 37
1avs_A_361avs   A     CACALCIUM ION S - 38
1avs_A_361avs   A     CACALCIUM ION E - 41
1be4_A_341be4   A     PCGCYCLIC GUANOSINE MONOPHOSPHATE H - 51
1be4_A_341be4   A     PCGCYCLIC GUANOSINE MONOPHOSPHATE Y - 52
1cpo_*_1471cpo   *     MANALPHA-D-MANNOSE D - 149
1cpo_*_1471cpo   *     MANALPHA-D-MANNOSE Y - 150
1cpo_*_1471cpo   *     MANALPHA-D-MANNOSE A - 151
1cpo_*_1471cpo   *     MANALPHA-D-MANNOSE D - 152
1cpo_*_1471cpo   *     MANALPHA-D-MANNOSE E - 155
1cpo_*_1471cpo   *     MANALPHA-D-MANNOSE I - 156
1cpo_*_1471cpo   *     MANALPHA-D-MANNOSE Q - 159
1cpo_*_1471cpo   *     MANALPHA-D-MANNOSE S - 162
1d4o_A_241d4o   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE P - 29
1d4o_A_241d4o   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 30
1d4o_A_241d4o   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Y - 31
1d4o_A_241d4o   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 32
1d4o_A_241d4o   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 33
1d4o_A_241d4o   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE A - 35
1dbt_A_311dbt   A     U5PURIDINE-5'-MONOPHOSPHATE K - 33
1dbt_A_311dbt   A     U5PURIDINE-5'-MONOPHOSPHATE G - 35
1dvi_A_2251dvi   A     CACALCIUM ION N - 225
1dvi_A_2251dvi   A     CACALCIUM ION D - 227
1dvi_A_2251dvi   A     CACALCIUM ION F - 228
1dvi_A_2251dvi   A     CACALCIUM ION D - 229
1dvi_A_2251dvi   A     CACALCIUM ION N - 230
1e3m_B_4981e3m   B     MSESELENOMETHIONINE R - 500
1e3m_B_4981e3m   B     MSESELENOMETHIONINE Y - 501
1e3m_B_4981e3m   B     MSESELENOMETHIONINE I - 502
1e3m_B_4981e3m   B     MSESELENOMETHIONINE I - 503
1e3m_B_4981e3m   B     MSESELENOMETHIONINE P - 504
1e3m_B_4981e3m   B     MSESELENOMETHIONINE L - 535
1e4m_M_4821e4m   M     NAGN-ACETYL-D-GLUCOSAMINE N - 482
1e4m_M_4821e4m   M     NAGN-ACETYL-D-GLUCOSAMINE T - 484
1e4m_M_4821e4m   M     NAGN-ACETYL-D-GLUCOSAMINE D - 485
1e4m_M_4821e4m   M     NAGN-ACETYL-D-GLUCOSAMINE I - 499
1f1e_A_1341f1e   A     MSESELENOMETHIONINE A - 143
1f1e_A_1341f1e   A     MSESELENOMETHIONINE I - 144
1f1e_A_1341f1e   A     MSESELENOMETHIONINE T - 145
1f1e_A_1341f1e   A     MSESELENOMETHIONINE Y - 146
1ggz_A_261ggz   A     CACALCIUM ION C - 26
1ggz_A_261ggz   A     CACALCIUM ION I - 27
1ggz_A_261ggz   A     CACALCIUM ION T - 28
1ggz_A_261ggz   A     CACALCIUM ION E - 31
1ggz_A_991ggz   A     CACALCIUM ION F - 99
1ggz_A_991ggz   A     CACALCIUM ION V - 100
1ggz_A_991ggz   A     CACALCIUM ION S - 101
1ggz_A_991ggz   A     CACALCIUM ION E - 104
1gs4_A_7681gs4   A     PO4PHOSPHATE ION K - 777
1ie9_A_2941ie9   A     VDX5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL Y - 295
1ie9_A_2941ie9   A     VDX5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL V - 300
1jmm_A_5261jmm   A     MSESELENOMETHIONINE F - 527
1jmm_A_5261jmm   A     MSESELENOMETHIONINE L - 528
1jp4_A_451jp4   A     PO4PHOSPHATE ION D - 45
1jp4_A_451jp4   A     MGMAGNESIUM ION D - 45
1jp4_A_451jp4   A     AMPADENOSINE MONOPHOSPHATE D - 45
1jp4_A_451jp4   A     PO4PHOSPHATE ION L - 46
1jp4_A_451jp4   A     MGMAGNESIUM ION L - 46
1jp4_A_451jp4   A     PO4PHOSPHATE ION D - 51
1jp4_A_451jp4   A     MGMAGNESIUM ION D - 51
1kic_A_2051kic   A     NOSINOSINE L - 210
1ko7_A_501ko7   A     PO4PHOSPHATE ION G - 54
1ko7_A_501ko7   A     PO4PHOSPHATE ION T - 55
1ko7_A_501ko7   A     PO4PHOSPHATE ION T - 56
1ko7_A_501ko7   A     PO4PHOSPHATE ION E - 57
1mr8_A_651mr8   A     OC1CALCIUM ION, 1 WATER COORDINATED A - 65
1mr8_A_651mr8   A     OC1CALCIUM ION, 1 WATER COORDINATED V - 66
1mr8_A_651mr8   A     OC1CALCIUM ION, 1 WATER COORDINATED N - 67
1mr8_A_651mr8   A     OC1CALCIUM ION, 1 WATER COORDINATED E - 70
1mum_A_421mum   A     MGMAGNESIUM ION G - 46
1mum_A_421mum   A     MGMAGNESIUM ION G - 47
1mxr_A_1801mxr   A     HGMERCURY (II) ION Y - 194
1mxr_A_1801mxr   A     HGMERCURY (II) ION L - 195
1mxr_A_1801mxr   A     HGMERCURY (II) ION C - 196
1mxr_A_1801mxr   A     HGMERCURY (II) ION L - 197
1mxr_A_1801mxr   A     HGMERCURY (II) ION M - 198
1mxr_A_1801mxr   A     HGMERCURY (II) ION S - 199
1mxr_A_1801mxr   A     HGMERCURY (II) ION V - 200
1mxr_A_1801mxr   A     FEFE (III) ION L - 203
1mxr_A_1801mxr   A     FEFE (III) ION E - 204
1n40_A_3041n40   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 309
1n7z_A_1871n7z   A     MSESELENOMETHIONINE R - 202
1on2_A_591on2   A     MNMANGANESE (II) ION L - 73
1on2_A_591on2   A     MNMANGANESE (II) ION H - 77
1orf_A_2261orf   A     MAIDEOXO-METHYLARGININE G - 226
1orf_A_2261orf   A     MAIDEOXO-METHYLARGININE V - 227
1orf_A_2261orf   A     MAIDEOXO-METHYLARGININE Y - 228
1otj_A_1501otj   A     TAU2-AMINOETHANESULFONIC ACID F - 155
1otj_A_1501otj   A     TAU2-AMINOETHANESULFONIC ACID S - 158
1q8f_A_1841q8f   A     GOLGLYCEROL L - 189
1qv0_A_1291qv0   A     CZHC2-HYDROPEROXY-COELENTERAZINE I - 130
1qv0_A_1291qv0   A     CZHC2-HYDROPEROXY-COELENTERAZINE W - 135
1qv0_A_1291qv0   A     CZHC2-HYDROPEROXY-COELENTERAZINE Y - 138
1qv0_A_1291qv0   A     CZHC2-HYDROPEROXY-COELENTERAZINE S - 142
1qwi_A_321qwi   A     MSESELENOMETHIONINE Y - 34
1qwi_A_321qwi   A     MSESELENOMETHIONINE G - 35
1qwi_A_321qwi   A     MSESELENOMETHIONINE F - 36
1qwi_A_321qwi   A     MSESELENOMETHIONINE R - 39
1qwi_A_321qwi   A     MSESELENOMETHIONINE F - 40
1qyi_A_2631qyi   A     MSESELENOMETHIONINE D - 268
1qyi_A_2631qyi   A     MSESELENOMETHIONINE L - 270
1qyi_A_2631qyi   A     MSESELENOMETHIONINE E - 271
1qyi_A_2631qyi   A     MSESELENOMETHIONINE A - 272
1qyi_A_2631qyi   A     MSESELENOMETHIONINE E - 273
1s3j_A_931s3j   A     MSESELENOMETHIONINE V - 108
1s3j_A_931s3j   A     MSESELENOMETHIONINE G - 111
1s3j_A_931s3j   A     MSESELENOMETHIONINE R - 112
1s3j_A_931s3j   A     MSESELENOMETHIONINE K - 113
1s3j_A_931s3j   A     MSESELENOMETHIONINE A - 114
1s6c_A_1891s6c   A     CACALCIUM ION I - 189
1s6c_A_1891s6c   A     CACALCIUM ION V - 190
1s6c_A_1891s6c   A     CACALCIUM ION T - 191
1s6c_A_1891s6c   A     CASS-(DIMETHYLARSENIC)CYSTEINE E - 194
1s6c_A_1891s6c   A     CACALCIUM ION E - 194
1s6c_A_1891s6c   A     CASS-(DIMETHYLARSENIC)CYSTEINE F - 195
1s6c_A_1891s6c   A     CACALCIUM ION F - 195
1s6c_A_1891s6c   A     CASS-(DIMETHYLARSENIC)CYSTEINE L - 196
1s6c_A_1891s6c   A     CACALCIUM ION L - 196
1s6c_A_1891s6c   A     CASS-(DIMETHYLARSENIC)CYSTEINE E - 197
1s6c_A_1891s6c   A     CACALCIUM ION E - 197
1so2_A_10571so2   A     HG91-DEOXY-1-[(2-HYDROXYETHYL)(NONANOYL)AMINO]HEXITOL K - 1070
1so2_A_10571so2   A     HG91-DEOXY-1-[(2-HYDROXYETHYL)(NONANOYL)AMINO]HEXITOL I - 1071
1so2_A_10571so2   A     HG91-DEOXY-1-[(2-HYDROXYETHYL)(NONANOYL)AMINO]HEXITOL W - 1072
1ubl_L_4921ubl   L     MGMAGNESIUM ION Q - 497
1ubl_L_4921ubl   L     MGMAGNESIUM ION L - 498
1ubl_L_4921ubl   L     MGMAGNESIUM ION V - 499
1ubl_L_4921ubl   L     MGMAGNESIUM ION V - 500
1ubl_L_4921ubl   L     FNE(MU-SULPHIDO)-BIS(MU-CYS,S)-[TRICARBONYLIRON-DI-(CYS, S)NICKEL(II)](FE-NI) V - 500
1ubl_L_4921ubl   L     FNE(MU-SULPHIDO)-BIS(MU-CYS,S)-[TRICARBONYLIRON-DI-(CYS, S)NICKEL(II)](FE-NI) P - 501
1ubl_L_4921ubl   L     FNE(MU-SULPHIDO)-BIS(MU-CYS,S)-[TRICARBONYLIRON-DI-(CYS, S)NICKEL(II)](FE-NI) S - 502
1ubl_L_4921ubl   L     MGMAGNESIUM ION T - 503
1ubl_L_4921ubl   L     FNE(MU-SULPHIDO)-BIS(MU-CYS,S)-[TRICARBONYLIRON-DI-(CYS, S)NICKEL(II)](FE-NI) T - 503
1v39_*_2211v39   *     MDG7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE E - 233
1v39_*_2211v39   *     MDG7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE Y - 237
1v39_*_2211v39   *     MDG7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE N - 240
1viu_A_591viu   A     MSESELENOMETHIONINE T - 59
1viu_A_591viu   A     MSESELENOMETHIONINE V - 60
2mas_A_1862mas   A     PIR2-(4-AMINO-PHENYL)-5-HYDROXYMETHYL-PYRROLIDINE-3,4-DIOL L - 191
2mas_A_1862mas   A     PIR2-(4-AMINO-PHENYL)-5-HYDROXYMETHYL-PYRROLIDINE-3,4-DIOL T - 194
2sak_*_542sak   *     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL V - 64
2sak_*_542sak   *     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL E - 65
2sak_*_542sak   *     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL W - 66
2sak_*_542sak   *     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL L - 68
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1be4_A_341be4   A NULC-GMP BINDING SITE.Y - 52
1gs4_A_7681gs4   A AC2PO4 BINDING SITE FOR CHAIN AK - 777
1mr8_A_651mr8   A EF2CALCIUM BINDING SITE IN EF HANDA - 65

Clusters included in this Subclass
CLUSTER: EH.0.1
CLUSTER: EH.1.3
CLUSTER: EH.2.3