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| Information on SUBCLASS 2.1.21 |
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Subclass Accession number: 2770
Subclass: 2.1.21 
Type: EH beta-alpha DB: ArchDB95 Image coordinates: 
 Consensus coordinates:
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Number of loops: 6 Average sequence ID (%) : 14.3 +/- 22.1 Average RMSD (Å) : 0.800 +/- 0.190 Consensus geometry
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| Consensus Sequence: | XXXpXX |
| (φψ)-conformation: | bbabaa |
| Pattern: | [AIMV] | [AGIT] | [agit] | [de] | [fimv] | [hl] | [DES] | x | x | [DKQST] | [aclp] | [EKPQ] | [APVY] | [lmv] |
| Conservation: | 1.100 | -0.856 | -0.467 | 0.806 | -0.053 | -0.900 | 2.118 | -0.592 | -1.138 | 0.145 | -1.171 | 1.214 | -0.526 | 0.321 |
| Loops included in this Subclass |
| Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
| 1gjw_A_410 | 1gjw | A | 411 | 424 | MIAEELDMEKDKAS | EEE----GGGHHHH | xbxxbaxaaaaaaa |
| 1n8f_A_140 | 1n8f | A | 140 | 153 | AAGEFLDMITPQYL | EEEE---SSTHHHH | bbbxxaxaaaaaaa |
| 1o4v_A_3 | 1o4v | A | 4 | 17 | VGIIMGSDSDLPVM | EEEEES-GGGHHHH | bbbbbabaaaaaaa |
| 1o60_A_91 | 1o60 | A | 92 | 105 | IITDVHEIYQCQPV | EEEE--SGGGHHHH | bbbbbabaaaaaaa |
| 1of8_A_155 | 1of8 | A | 155 | 168 | IGSEMLDTISPQYL | EEEE--SSSTHHHH | bbbxxaxaaaaaaa |
| 1pe1_A_1077 | 1pe1 | A | 1078 | 1091 | ITTDIHESWQAEPV | EEEE-SSGGGHHHH | bbbbbabaaaaaaa |
| PDB ligands within a cut-off distance of 6 Å in this subclass |
| Loop | PDB | Chain | Ligands | Residue |
| 1gjw_A_410 | 1gjw | A | GLCGLUCOSE | A - 413 |
| 1gjw_A_410 | 1gjw | A | MALMALTOSE | E - 414 |
| 1gjw_A_410 | 1gjw | A | GLCGLUCOSE | E - 414 |
| 1gjw_A_410 | 1gjw | A | GLCGLUCOSE | E - 415 |
| 1gjw_A_410 | 1gjw | A | GLCGLUCOSE | K - 420 |
| 1gjw_A_410 | 1gjw | A | GLCGLUCOSE | A - 423 |
| 1gjw_A_410 | 1gjw | A | GLCGLUCOSE | S - 424 |
| 1gjw_A_410 | 1gjw | A | GLCGLUCOSE | A - 427 |
| 1n8f_A_140 | 1n8f | A | PEPPHOSPHOENOLPYRUVATE | E - 143 |
| 1o60_A_91 | 1o60 | A | MSESELENOMETHIONINE | V - 96 |
| 1o60_A_91 | 1o60 | A | MSESELENOMETHIONINE | Y - 100 |
| 1o60_A_91 | 1o60 | A | MSESELENOMETHIONINE | Q - 101 |
| 1o60_A_91 | 1o60 | A | MSESELENOMETHIONINE | C - 102 |
| 1o60_A_91 | 1o60 | A | MSESELENOMETHIONINE | P - 104 |
| 1o60_A_91 | 1o60 | A | MSESELENOMETHIONINE | V - 105 |
| 1of8_A_155 | 1of8 | A | PEPPHOSPHOENOLPYRUVATE | E - 158 |
| 1of8_A_155 | 1of8 | A | G3P3-PHOSPHOGLYCEROL | E - 158 |
| 1of8_A_155 | 1of8 | A | GOLGLYCEROL | L - 160 |
| 1of8_A_155 | 1of8 | A | GOLGLYCEROL | D - 161 |
| 1pe1_A_1077 | 1pe1 | A | 2PG2-PHOSPHOGLYCERIC ACID | D - 1081 |
| 1pe1_A_1077 | 1pe1 | A | 2PG2-PHOSPHOGLYCERIC ACID | H - 1083 |
| PDB Site Annotated loops in this subclass |
| Loop | PDB | Chain | Site | Residue |
| 1gjw_A_410 | 1gjw | A | GLCGLC BINDING SITE FOR CHAIN A | E - 415 |
| 1gjw_A_410 | 1gjw | A | GLCGLC BINDING SITE FOR CHAIN A | A - 423 |
| 1gjw_A_410 | 1gjw | A | GLCGLC BINDING SITE FOR CHAIN A | S - 424 |
| 1gjw_A_410 | 1gjw | A | GLCGLC BINDING SITE FOR CHAIN A | A - 427 |
| 1of8_A_155 | 1of8 | A | AC2PEP BINDING SITE FOR CHAIN A | E - 158 |
| 1of8_A_155 | 1of8 | A | AC5GOL BINDING SITE FOR CHAIN B | D - 161 |
| Clusters included in this Subclass |
| CLUSTER: EH.5.103 |
| CLUSTER: EH.7.78 |
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