Logo
Information on SUBCLASS 2.1.5
Subclass Accession number: 2754
Subclass: 2.1.5 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 47

Average sequence ID (%) : 10.3 +/- 14.1
Average RMSD (Å) : 0.674 +/- 0.191

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 135-180 rho (°): 0-45
Consensus Sequence: XXXpXX
(φψ)-conformation: bbabaa
Pattern: [afgiltv]xxx[degknqrst]x[adegknqrst]x[afgiklmtv][adegnpqst]x[afgilmv]
Conservation:0.545-0.937-0.160-1.0452.461-0.9430.397-0.626-0.2080.137-0.5450.923
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1bjn_A_2991bjn   A302313FQLADSALDKLFEEESSGGGHHHHbbxabaaaaaaa
1c7q_A_2621c7q   A265276LVNYEPSLHYVSEEESSGGGHHHHxbbabaaaaaaa
1cdo_A_2191cdo   A222233AVDLNPDKFEKAEE-S-GGGHHHHxbbaxaaaaaaa
1coz_A_671coz   A6980IPEKNWEQKKQDEEE--STTHHHHbxbabaaaaaaa
1d1t_A_2181d1t   A221232GIDLNKDKFEKAEE-S-GGGHHHHxbbaxaaaaaaa
1d9e_A_10911d9e   A10941105TDVHEPSQAQPVEE--SGGGHHHHbxbabaaaaaaa
1dkr_A_1681dkr   A170181IVSPDHGGVTRAEEESSTT-HHHHxbxabaaaaaaa
1e3i_A_2221e3i   A225236AIDINGEKFPKAEE-S-GGGHHHHbbbabaaaaaaa
1ejb_A_521ejb   A5566ETVPGSYELPWGEE-SSGGGHHHHbbbabaaaaaaa
1ek8_A_641ek8   A6778INVFDRSMSPAVEEESSGGGHHHHbbxabaaaaaaa
1ezv_A_3251ezv   A331342TATRNVTMIDDLEEES-TT-HHHHbbbaxaaaaaaa
1gyt_A_1561gyt   A159170FNVPTRRELTSGEE-SSGGGHHHHxxbabaaaaaaa
1het_A_2181het   A221232GVDINKDKFAKAEE-S-GGGHHHHxbbabaaaaaaa
1id1_A_1031id1   A105116LAVSDSKNLNKIEE-SSGGGHHHHbbbabaaaaaaa
1ijb_A_6751ijb   A675686FVLSSVDELEQQEEESSGGGHHHHbbbabaaaaaaa
1is1_A_641is1   A6778ITVFDKELTQKVEEESSTTTHHHHbbxaxaaaaaaa
1izc_A_2501izc   A252263GGALSVDMVPSLEE-SSGGGHHHHbbbabaaaaaaa
1jd1_A_741jd1   A7990IFLADINHFAEFEEES-GGGHHHHbbbabaaaaaaa
1jmj_A_3341jmj   A339350VVPHKMSGMKTLEEESSTTHHHHHbbxaxaaaaaaa
1jwq_A_921jwq   A94105TYYQRSASKAFAEEE-SGGGHHHHbbbabaaaaaaa
1khd_A_2011khd   A204215IGVYSPELVLPIEE-SSGGGHHHHbxbabaaaaaaa
1kz1_A_541kz1   A5768ESVPGSWELPQGEE-SSGGGHHHHbbbabaaaaaaa
1l7d_A_1971l7d   A200211ATDVRAATKEQVEE-S-STTHHHHbbbaxaaaaaaa
1lss_A_941lss   A96107ARISEIEYKDVFEE-SSTTHHHHHbxbaxaaaaaaa
1n0u_A_4891n0u   A493504VEVKNANDLPKLEEESSGGGHHHHbbxabaaaaaaa
1n57_A_2571n57   A258269LTGDSPFAANALEEESSGGGHHHHbbbabaaaaaaa
1nqu_A_481nqu   A5162VRVPGSWEIPVAEEESSGGGHHHHbbbabaaaaaaa
1o1z_A_931o1z   A96107IEIKEREAADAVEEE--GGGHHHHxxxabaaaaaaa
1o89_A_1741o89   A176187AVSGRESTHEYLEEES-GGGHHHHxbbaxaaaaaaa
1p0c_A_12171p0c   A12201231GVGTHKDKFPKAEE-S-GGGHHHHxbbabaaaaaaa
1qah_A_751qah   A8091VLLADINDFGTVEEES-GGGHHHHbbbabaaaaaaa
1qd9_A_711qd9   A7687VFIADMEQFAEVEEES-GGGHHHHbbbabaaaaaaa
1qsg_A_341qsg   A3748FTYQNDKLKGRVEEESSTTTHHHHbbbabaaaaaaa
1qu9_A_711qu9   A7687VFVKDLNDFATVEEES-GGGHHHHbbbabaaaaaaa
1qyi_A_3611qyi   A361372YVINHLGELRGVEEESSGGGHHHHbbbabaaaaaaa
1qz9_A_1481qz9   A150161RLVDSPEELPQAEEESSGGGHHHHbxbabaaaaaaa
1rdr_*_4031rdr   -403413.WTKDPRNTQDH.EES-TTSHHHH.bbabaaaaaaa
1rql_A_2441rql   A244255FTIETMQELESVEEESSGGGHHHHbbbabaaaaaaa
1rvv_1_481rvv   15162AWVPGAFEIPFAEEESSGGGHHHHbxbabaaaaaaa
1sek_*_2391sek   -244255ILPNQVDGITALEEESSTTTHHHHbbxaxaaaaaaa
1tgo_A_371tgo   A4051ALLKDDSAIEDVEEESSGGGHHHHbxbabaaaaaaa
1ufk_A_1441ufk   A147158GVDIDPMVLPQAEEES-GGGHHHHbbbabaaaaaaa
1uuf_A_2001uuf   A203214AFTTSEAKREAAEEESSGGGHHHHxbbabaaaaaaa
1v7z_A_1131v7z   A116127LMNGHYENSMFIEEE-SGGGHHHHxbxabaaaaaaa
1v8g_A_1871v8g   A190201LGVFSPEWLAPMEE-SSGGGHHHHbxbabaaaaaaa
2scu_A_1442scu   A149160IVSRSGTLTYEAEEES-SHHHHHHbbbabaaaaaaa
8abp_*_608abp   -6374ICTPDPKLGSAIEE-S-GGGHHHHbbxabaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1cdo_A_2191cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 223
1cdo_A_2191cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE D - 224
1cdo_A_2191cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 225
1cdo_A_2191cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 226
1cdo_A_2191cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE K - 229
1d1t_A_2181d1t   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 222
1d1t_A_2181d1t   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE D - 223
1d1t_A_2181d1t   A     ZNZINC ION L - 224
1d1t_A_2181d1t   A     ACTACETATE ION L - 224
1d1t_A_2181d1t   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 224
1d1t_A_2181d1t   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 225
1d1t_A_2181d1t   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE K - 228
1d1t_A_2181d1t   A     CACCACODYLATE ION M - 233
1d1t_A_2181d1t   A     CACCACODYLATE ION A - 234
1d1t_A_2181d1t   A     CACCACODYLATE ION V - 235
1e3i_A_2221e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 226
1e3i_A_2221e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE D - 227
1e3i_A_2221e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 228
1e3i_A_2221e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 229
1e3i_A_2221e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE K - 232
1ejb_A_521ejb   A     INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID P - 58
1ejb_A_521ejb   A     INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID G - 59
1ejb_A_521ejb   A     INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID S - 60
1ejb_A_521ejb   A     INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID Y - 61
1ejb_A_521ejb   A     INJ5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID E - 62
1ek8_A_641ek8   A     HGMERCURY (II) ION V - 69
1ek8_A_641ek8   A     HGMERCURY (II) ION F - 70
1ek8_A_641ek8   A     HGMERCURY (II) ION D - 71
1ek8_A_641ek8   A     HGMERCURY (II) ION R - 72
1ek8_A_641ek8   A     HGMERCURY (II) ION M - 74
1het_A_2181het   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 222
1het_A_2181het   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 224
1lss_A_941lss   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE R - 97
1lss_A_941lss   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE S - 99
1lss_A_941lss   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE E - 100
1n0u_A_4891n0u   A     SO1[1R-(1.ALPHA.,3A.BETA.,4.BETA.,4A.BETA.,7.BETA., 7A.ALPHA.,8A.BETA.)]8A-[(6-DEOXY-4-O-METHYL-BETA-D-ALTROPYRANOSYLOXY)METHYL]-4-FORMYL-4,4A,5,6,7,7A,8,8A-OCTAHYDRO-7-METHYL-3-(1-METHYLETHYL)-1,4-METHANO-S-INDACENE-3A(1H)-CARBOXYLIC ACID Q - 490
1n57_A_2571n57   A     MSESELENOMETHIONINE L - 257
1n57_A_2571n57   A     MSESELENOMETHIONINE L - 258
1n57_A_2571n57   A     MSESELENOMETHIONINE L - 272
1n57_A_2571n57   A     MSESELENOMETHIONINE A - 273
1n57_A_2571n57   A     MSESELENOMETHIONINE A - 274
1n57_A_2571n57   A     MSESELENOMETHIONINE Q - 275
1nqu_A_481nqu   A     RDL6,7-DIOXO-5H-8-RIBITYLAMINOLUMAZINE P - 54
1nqu_A_481nqu   A     RDL6,7-DIOXO-5H-8-RIBITYLAMINOLUMAZINE G - 55
1nqu_A_481nqu   A     RDL6,7-DIOXO-5H-8-RIBITYLAMINOLUMAZINE S - 56
1nqu_A_481nqu   A     RDL6,7-DIOXO-5H-8-RIBITYLAMINOLUMAZINE W - 57
1nqu_A_481nqu   A     RDL6,7-DIOXO-5H-8-RIBITYLAMINOLUMAZINE E - 58
1p0c_A_12171p0c   A     CRYPROPANE-1,2,3-TRIOL V - 1221
1p0c_A_12171p0c   A     CRYPROPANE-1,2,3-TRIOL G - 1222
1p0c_A_12171p0c   A     CRYPROPANE-1,2,3-TRIOL T - 1223
1p0c_A_12171p0c   A     CRYPROPANE-1,2,3-TRIOL H - 1224
1p0c_A_12171p0c   A     CRYPROPANE-1,2,3-TRIOL K - 1227
1qd9_A_711qd9   A     HGMERCURY (II) ION V - 76
1qd9_A_711qd9   A     HGMERCURY (II) ION I - 78
1qd9_A_711qd9   A     HGMERCURY (II) ION M - 81
1qd9_A_711qd9   A     HGMERCURY (II) ION F - 84
1qd9_A_711qd9   A     HGMERCURY (II) ION V - 87
1qd9_A_711qd9   A     HGMERCURY (II) ION N - 88
1qsg_A_341qsg   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE Y - 39
1qsg_A_341qsg   A     GLCGLUCOSE Q - 40
1qsg_A_341qsg   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE Q - 40
1qsg_A_341qsg   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 44
1qu9_A_711qu9   A     CSPS-PHOSPHOCYSTEINE T - 74
1qu9_A_711qu9   A     CSPS-PHOSPHOCYSTEINE T - 75
1qu9_A_711qu9   A     CSPS-PHOSPHOCYSTEINE V - 76
1qu9_A_711qu9   A     CSPS-PHOSPHOCYSTEINE F - 77
1qu9_A_711qu9   A     CSPS-PHOSPHOCYSTEINE V - 78
1qu9_A_711qu9   A     CSPS-PHOSPHOCYSTEINE L - 81
1qu9_A_711qu9   A     CSPS-PHOSPHOCYSTEINE F - 84
1qu9_A_711qu9   A     CSPS-PHOSPHOCYSTEINE N - 88
1rvv_1_481rvv   1     INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE P - 54
1rvv_1_481rvv   1     INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE G - 55
1rvv_1_481rvv   1     INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE A - 56
1rvv_1_481rvv   1     INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE F - 57
1rvv_1_481rvv   1     INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE E - 58
1rvv_1_481rvv   1     INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE I - 59
1v7z_A_1131v7z   A     MNMANGANESE (II) ION G - 119
1v7z_A_1131v7z   A     ZNZINC ION G - 119
1v7z_A_1131v7z   A     CRNN-[(E)-AMINO(IMINO)METHYL]-N-METHYLGLYCINE G - 119
1v7z_A_1131v7z   A     MNMANGANESE (II) ION H - 120
1v7z_A_1131v7z   A     ZNZINC ION H - 120
1v7z_A_1131v7z   A     CRNN-[(E)-AMINO(IMINO)METHYL]-N-METHYLGLYCINE H - 120
1v7z_A_1131v7z   A     MNMANGANESE (II) ION Y - 121
1v7z_A_1131v7z   A     CRNN-[(E)-AMINO(IMINO)METHYL]-N-METHYLGLYCINE Y - 121
1v7z_A_1131v7z   A     MNMANGANESE (II) ION E - 122
1v7z_A_1131v7z   A     CRNN-[(E)-AMINO(IMINO)METHYL]-N-METHYLGLYCINE E - 122
2scu_A_1442scu   A     NEPN1-PHOSPHONOHISTIDINE R - 152
2scu_A_1442scu   A     NEPN1-PHOSPHONOHISTIDINE S - 153
2scu_A_1442scu   A     NEPN1-PHOSPHONOHISTIDINE G - 154
2scu_A_1442scu   A     COACOENZYME A G - 154
2scu_A_1442scu   A     NEPN1-PHOSPHONOHISTIDINE T - 155
2scu_A_1442scu   A     COACOENZYME A T - 155
2scu_A_1442scu   A     NEPN1-PHOSPHONOHISTIDINE L - 156
2scu_A_1442scu   A     COACOENZYME A Y - 158
8abp_*_608abp   *     GLAALPHA D-GALACTOSE C - 64
8abp_*_608abp   *     GLBBETA-D-GALACTOSE C - 64

Clusters included in this Subclass
CLUSTER: EH.4.397
CLUSTER: EH.4.45
CLUSTER: EH.4.73
CLUSTER: EH.4.80
CLUSTER: EH.5.3
CLUSTER: EH.5.361
CLUSTER: EH.7.4