ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.20.1

Subclass Accession number: 7381
Subclass: 4.20.1

Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 11

Average sequence ID (%) : 19.3 +/- 26.0
Average RMSD (Å) : 0.936 +/- 0.364

Consensus geometry

d (Å): 11

delta (°): 45-90

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	XXXXhXpX
(φψ)-conformation:	bbaaalaa

Pattern:	[fhim]	x	[acstv]	[aps]	x	x	[afgly]	[aegknqrs]	[dknqt]	[EGR]	x	[AEGNQS]	x	[ags]	[aeklm]	[agnsv]	[afil]
Conservation:	0.161	-0.281	-0.187	0.892	0.755	-1.204	-0.959	-0.807	-0.699	2.220	-0.984	1.227	0.300	1.496	-0.721	-0.589	-0.620

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1afs_A_48	1afs	A	49	65	FDSAYLYEVEEEVGQAI	EE--TTTT-HHHHHHHH	bbbbaaalaaaaaaaaa
1ah4_*_41	1ah4	-	42	58	IDCAHVYQNENEVGLGL	EE--GGGS-HHHHHHHH	bbbbaaavNaaaaaaaa
1foh_A_360	1foh	A	360	376	HTHSPKAGQGMNTSMMD	EE--STT--HHHHHHHH	bbbxaaalaaaaaaaaa
1frb_*_41	1frb	-	42	58	IDCAYAYCNENEVGEAI	EE--GGGT-HHHHHHHH	bxbbaaalNaaaaaaaa
1hqt_A_43	1hqt	A	44	60	IDCAAIFGNELEIGEAL	EE--GGGS-HHHHHHHH	bbbbaaalNaaaaaaaa
1hzy_A_198	1hzy	A	200	216	THTAASQRDGEQQAAIF	EE--GGGTHHHHHHHHH	bbbbaaavaaaaaaaaa
1j96_A_48	1j96	A	49	65	IDSAHVYNNEEQVGLAI	EE--GGGS-HHHHHHHH	bbbbaaalNaaaaaaaa
1k0i_A_289	1k0i	A	289	305	HIVPPTGAKGLNLAASD	EE--GGGT-HHHHHHHH	bbbxaaalaaaaaaaaa
1lw3_A_159	1lw3	A	163	179	FAHKPEGRTRRSIFENL	EE--GGG--HHHHHHHH	bbbxaaalaaaaaaaaa
1mzr_A_45	1mzr	A	46	62	IDTAAAYKNEEGVGKAL	EE--GGGT-HHHHHHHH	bbbbaaalaaaaaaaaa
1nvm_A_196	1nvm	A	199	215	MHAHHNLSLGVANSIVA	EE-B-TTS-HHHHHHHH	bbxbaaavaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1afs_A_48	1afs	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	D - 50
1afs_A_48	1afs	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	S - 51
1afs_A_48	1afs	A	TESTESTOSTERONE	A - 52
1afs_A_48	1afs	A	TESTESTOSTERONE	L - 54
1afs_A_48	1afs	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	Y - 55
1afs_A_48	1afs	A	TESTESTOSTERONE	Y - 55
1ah4_*_41	1ah4	*	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	D - 43
1ah4_*_41	1ah4	*	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	C - 44
1ah4_*_41	1ah4	*	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	Y - 48
1foh_A_360	1foh	A	FADFLAVIN-ADENINE DINUCLEOTIDE	H - 362
1foh_A_360	1foh	A	FADFLAVIN-ADENINE DINUCLEOTIDE	P - 364
1foh_A_360	1foh	A	IPHPHENOL	P - 364
1foh_A_360	1foh	A	IPHPHENOL	K - 365
1foh_A_360	1foh	A	IPHPHENOL	A - 366
1foh_A_360	1foh	A	FADFLAVIN-ADENINE DINUCLEOTIDE	G - 367
1foh_A_360	1foh	A	IPHPHENOL	G - 367
1foh_A_360	1foh	A	FADFLAVIN-ADENINE DINUCLEOTIDE	Q - 368
1foh_A_360	1foh	A	IPHPHENOL	Q - 368
1foh_A_360	1foh	A	FADFLAVIN-ADENINE DINUCLEOTIDE	G - 369
1foh_A_360	1foh	A	FADFLAVIN-ADENINE DINUCLEOTIDE	M - 370
1foh_A_360	1foh	A	FADFLAVIN-ADENINE DINUCLEOTIDE	N - 371
1foh_A_360	1foh	A	FADFLAVIN-ADENINE DINUCLEOTIDE	S - 373
1foh_A_360	1foh	A	FADFLAVIN-ADENINE DINUCLEOTIDE	M - 374
1frb_*_41	1frb	*	ZST3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID	A - 45
1frb_*_41	1frb	*	ZST3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID	A - 47
1frb_*_41	1frb	*	ZST3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID	Y - 48
1hqt_A_43	1hqt	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	D - 45
1hqt_A_43	1hqt	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	C - 46
1hqt_A_43	1hqt	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	F - 50
1hzy_A_198	1hzy	A	ZNZINC ION	T - 200
1hzy_A_198	1hzy	A	CBXCARBOXY GROUP	T - 200
1hzy_A_198	1hzy	A	ZNZINC ION	H - 201
1hzy_A_198	1hzy	A	CBXCARBOXY GROUP	H - 201
1hzy_A_198	1hzy	A	EGLETHYLENE GLYCOL	H - 201
1hzy_A_198	1hzy	A	ZNZINC ION	T - 202
1j96_A_48	1j96	A	ACTACETATE ION	A - 52
1j96_A_48	1j96	A	ACTACETATE ION	V - 54
1j96_A_48	1j96	A	TESTESTOSTERONE	V - 54
1j96_A_48	1j96	A	ACTACETATE ION	Y - 55
1k0i_A_289	1k0i	A	FADFLAVIN-ADENINE DINUCLEOTIDE	H - 289
1k0i_A_289	1k0i	A	PHBP-HYDROXYBENZOIC ACID	H - 289
1k0i_A_289	1k0i	A	FADFLAVIN-ADENINE DINUCLEOTIDE	I - 290
1k0i_A_289	1k0i	A	PHBP-HYDROXYBENZOIC ACID	I - 290
1k0i_A_289	1k0i	A	FADFLAVIN-ADENINE DINUCLEOTIDE	V - 291
1k0i_A_289	1k0i	A	PHBP-HYDROXYBENZOIC ACID	V - 291
1k0i_A_289	1k0i	A	FADFLAVIN-ADENINE DINUCLEOTIDE	P - 293
1k0i_A_289	1k0i	A	PHBP-HYDROXYBENZOIC ACID	P - 293
1k0i_A_289	1k0i	A	PHBP-HYDROXYBENZOIC ACID	T - 294
1k0i_A_289	1k0i	A	PHBP-HYDROXYBENZOIC ACID	G - 295
1k0i_A_289	1k0i	A	FADFLAVIN-ADENINE DINUCLEOTIDE	A - 296
1k0i_A_289	1k0i	A	PHBP-HYDROXYBENZOIC ACID	A - 296
1k0i_A_289	1k0i	A	FADFLAVIN-ADENINE DINUCLEOTIDE	K - 297
1k0i_A_289	1k0i	A	FADFLAVIN-ADENINE DINUCLEOTIDE	G - 298
1k0i_A_289	1k0i	A	PHBP-HYDROXYBENZOIC ACID	G - 298
1k0i_A_289	1k0i	A	FADFLAVIN-ADENINE DINUCLEOTIDE	L - 299
1k0i_A_289	1k0i	A	FADFLAVIN-ADENINE DINUCLEOTIDE	N - 300
1k0i_A_289	1k0i	A	FADFLAVIN-ADENINE DINUCLEOTIDE	A - 302
1mzr_A_45	1mzr	A	GOLGLYCEROL	A - 51
1mzr_A_45	1mzr	A	GOLGLYCEROL	Y - 52
1mzr_A_45	1mzr	A	GOLGLYCEROL	K - 53
1nvm_A_196	1nvm	A	MNMANGANESE (II) ION	H - 200
1nvm_A_196	1nvm	A	OXLOXALATE ION	H - 200
1nvm_A_196	1nvm	A	MNMANGANESE (II) ION	A - 201
1nvm_A_196	1nvm	A	MNMANGANESE (II) ION	H - 202
1nvm_A_196	1nvm	A	OXLOXALATE ION	H - 202
1nvm_A_196	1nvm	A	MPD2-METHYL-2,4-PENTANEDIOL	L - 205

Clusters included in this Subclass