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Information on SUBCLASS 6.2.3
Subclass Accession number: 3323
Subclass: 6.2.3 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 5.3 (>75 %)  5.3.1 (>75 %)  5.3.1.5
GO : GO:0000287 (>75 %)  GO:0003677 (>75 %)  GO:0004518 (>75 %)  GO:0004519 (>75 %)  GO:0009045 (>75 %)  GO:0016788 (>75 %)  GO:0016853 (>75 %)  GO:0016860 (>75 %)  GO:0016861 (>75 %)  
SCOP : 51658 (>75 %)  51665 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 67.9 +/- 8.7
Average RMSD (Å) : 0.275 +/- 0.126

Consensus geometry
d (Å): 21 delta (°): 45-90 theta (°): 135-180 rho (°): 315-360
Consensus Sequence: hphXRTEDpp
(φψ)-conformation: bbppaabpaa
Pattern: [R][H][F][D][AFY][HK][AP]x[R][T][DE][DG][EFY][DE][G][V][W][ADE]x[A][AKR][AG][CN][IM][RS]x[Y][L][IL][L][K][E][R][A][AEKL][A][F][R][AE]
Conservation:0.5421.9080.9970.997-0.927-0.550-0.545-1.5790.5420.542-0.038-0.514-0.9720.0370.9970.0863.274-1.150-1.0830.086-1.004-0.569-0.666-0.380-0.822-1.2441.4530.086-0.3680.0860.5420.5420.5420.086-1.6210.0860.9970.542-0.940
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1bxc_A_2831bxc   A283321RHFDAHALRTEDEEGVWAFARGCMRTYLILKERAEAFREEEE-----TT--HHHHHHHHHHHHHHHHHHHHHHHHHHHbxxxbbxpaabxaaaaaaaaaaaaaaaaaaaaaaaaaaa
1mnz_A_2841mnz   A284322RHFDFKPPRTEDFDGVWASAAGCMRNYLILKERAAAFRAEEE-----TT--HHHHHHHHHHHHHHHHHHHHHHHHHHHxxbbbbppaaxxaaaaaaaaaaaaaaaaaaaaaaaaaaa
1xim_A_2891xim   A289327RHFDYKPSRTEDYDGVWESAKANIRMYLLLKERAKAFRAEEE-----TT--HHHHHHHHHHHHHHHHHHHHHHHHHHHbxxbbbwpaabbaaaaaaaaaaaaaaaaaaaaaaaaaaa
4xia_A_2894xia   A289327RHFDYKPSRTDGYDGVWDSAKANMSMYLLLKERALAFRAEEE-----TTS-HHHHHHHHHHHHHHHHHHHHHHHHHHHbxbbbbxpaaxxaaaaaaaaaaaaaaaaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1mnz_A_2841mnz   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL H - 285
1mnz_A_2841mnz   A     MGMAGNESIUM ION D - 287
1mnz_A_2841mnz   A     CACALCIUM ION D - 287
1mnz_A_2841mnz   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL D - 287
1mnz_A_2841mnz   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL K - 289
1mnz_A_2841mnz   A     MPD2-METHYL-2,4-PENTANEDIOL K - 289
1xim_A_2891xim   A     COCOBALT (II) ION D - 292
1xim_A_2891xim   A     XYLD-XYLITOL D - 292
1xim_A_2891xim   A     COCOBALT (II) ION K - 294
1xim_A_2891xim   A     XYLD-XYLITOL K - 294
4xia_A_2894xia   A     SORD-SORBITOL H - 290
4xia_A_2894xia   A     MGMAGNESIUM ION D - 292
4xia_A_2894xia   A     SORD-SORBITOL D - 292
4xia_A_2894xia   A     SORD-SORBITOL K - 294

Clusters included in this Subclass
CLUSTER: EH.8.53