ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.21.1

Subclass Accession number: 314
Subclass: 4.21.1

Type: HE alpha-beta
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : - (>75 %)  1 (>75 %)  1.7 (>75 %)  1.7.2 (>75 %)  14 (>75 %)
GO : GO:0004497 (>75 %)  GO:0016661 (>75 %)  GO:0016662 (>75 %)  GO:0046914 (>75 %)
SCOP : 48263 (>75 %)  48264 (>75 %)  48265 (>75 %)

Number of loops: 5

Average sequence ID (%) : 20.0 +/- 18.1
Average RMSD (Å) : 0.380 +/- 0.303

Consensus geometry

d (Å): 7

delta (°): 45-90

theta (°): 45-90

rho (°): 135-180

Consensus Sequence:	hpchppFS
(φψ)-conformation:	aapaaabb

Pattern:	[KMR]	[EMQ]	[AILV]	[GLMY]	[EGKNQ]	[DNQ]	[fpy]	[EGQRS]	x	[FT]	[KS]
Conservation:	0.065	0.505	0.161	-1.307	-0.661	1.224	-0.750	-0.914	-0.999	1.563	1.112

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1cpt_*_57	1cpt	-	61	71	MQIGKQPGLFS	HHHHH-TTTEE	aaaaabaaabx
1dz4_A_68	1dz4	A	72	82	REAYEDYRHFS	HHHHH-TTTEE	aaaaaxaaabx
1ihu_A_482	1ihu	A	482	492	MMLLQDPERTK	HHHHH-TTTEE	aaaaaxaaabb
1io7_A_26	1io7	A	30	40	KEVLNNFSKFS	HHHHH-TTTEE	aaaaaxaaabx
1lfk_A_48	1lfk	A	52	62	RQVMGDHQQFS	HHHHH-TTTEE	aaaaaxaaabx

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1cpt_*_57	1cpt	*	HEMPROTOPORPHYRIN IX CONTAINING FE	G - 64
1dz4_A_68	1dz4	A	HEMPROTOPORPHYRIN IX CONTAINING FE	Y - 75
1ihu_A_482	1ihu	A	ADPADENOSINE-5'-DIPHOSPHATE	V - 496
1io7_A_26	1io7	A	HEMPROTOPORPHYRIN IX CONTAINING FE	L - 33
1lfk_A_48	1lfk	A	HEMPROTOPORPHYRIN IX CONTAINING FE	M - 55
1lfk_A_48	1lfk	A	HEMPROTOPORPHYRIN IX CONTAINING FE	T - 63

Clusters included in this Subclass

CLUSTER: HE.3.48