Information on SUBCLASS 5.12.1 |
Subclass Accession number: 371
Subclass: 5.12.1 Type: HE alpha-beta DB: ArchDB40 Image coordinates: Consensus coordinates: Conserved Annotation EC : 2.1 (>75 %) 2.1.1 (>75 %) 22 (>75 %) 3 (>75 %) 4 (>75 %) GO : GO:0003677 (>75 %) GO:0005489 (>75 %) GO:0005506 (>75 %) GO:0008168 (>75 %) GO:0016741 (>75 %) GO:0046914 (>75 %) SCOP : 52128 (>75 %) 52129 (>75 %) 52130 (>75 %) 54861 (>75 %) 54862 (>75 %) |
Number of loops: 6 Average sequence ID (%) : 15.6 +/- 16.5 Average RMSD (Å) : 1.150 +/- 0.259 Consensus geometry
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Consensus Sequence: | XXhXXhpXh |
(φψ)-conformation: | aappplpbb |
Pattern: | x | [EHKQT] | [dgv] | [AFLY] | x | [DEKRSW] | x | [flt] | [AEK] | [gnv] | [ALMV] | [KPR] | x | [gq] | [EGS] | x | [FILV] | [dstv] |
Conservation: | -1.199 | 0.629 | -0.955 | 0.406 | -1.326 | -0.632 | -1.076 | -0.202 | 0.770 | 0.234 | 1.011 | 1.462 | -1.028 | 0.683 | 1.030 | -0.874 | 1.761 | -0.694 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1ajs_A_170 | 1ajs | A | 170 | 187 | LQGFLSDLENAPEFSIFV | HHHHHHHHHHS-TT-EEE | aaaaaaaaaaxppvpxbx |
1d7y_A_132 | 1d7y | A | 132 | 149 | LEDARRIQAGLRPQSRLL | HHHHHHHHHH--TT-EEE | aaaaaaaaaaxxxvxbbb |
1mgt_A_91 | 1mgt | A | 94 | 111 | KKVYEWLTKNVKRGSVIT | HHHHHHHHHHS-TT--EE | aaaaaaaaaaxxpvbbbx |
1nw3_A_247 | 1nw3 | A | 250 | 267 | DHQLKERFANMKEGGRIV | HHHHHHHHTT--TT-EEE | aaaaaaaaaaxxpvxbbb |
1odo_A_108 | 1odo | A | 122 | 139 | VTGLVDRLAELPAGEPVD | HHHHHHHHHHS-TTS-EE | aaaaaaaaaaxpxvxxbx |
1qnt_A_94 | 1qnt | A | 96 | 113 | RQVLWKLLKVVKFGEVIS | HHHHHHHHHH--TT--EE | aaaaaaaaaaxxxvbbbx |
PDB ligands within a cut-off distance of 6 Å in this subclass |
Loop | PDB | Chain | Ligands | Residue |
1ajs_A_170 | 1ajs | A | PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID | H - 189 |
1nw3_A_247 | 1nw3 | A | SAMS-ADENOSYLMETHIONINE | V - 249 |
Clusters included in this Subclass |
CLUSTER: HE.5.174 |
CLUSTER: HE.6.48 |