Logo
Information on SUBCLASS 6.5.1
Subclass Accession number: 8644
Subclass: 6.5.1 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 15

Average sequence ID (%) : 31.8 +/- 31.1
Average RMSD (Å) : 0.627 +/- 0.252

Consensus geometry
d (Å): 13 delta (°): 45-90 theta (°): 135-180 rho (°): 225-270
Consensus Sequence: XhchpXGXXh
(φψ)-conformation: aalpbpgpbb
Pattern: x[AFGIMV][AFILMV][dekn][iltvwy][AGKLV][DGKN][ILV][DEGKT][kpqr][DG]x[nrst][CILV][aglvy]x[AFILMV]
Conservation:-1.140-0.707-0.036-0.754-1.017-0.4120.3041.536-0.192-0.2722.825-0.123-0.3100.934-0.872-0.1190.353
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1amu_A_671amu   A7995RIFIEKGIGKDTLVGIMHHHHHTT--TT-EEEEEaaaaaavxbpvxxbxbb
1cdo_A_1761cdo   A183199AAVNTAKVEPGSTCAVFHHHTTT---TT-EEEEEaaaaaavpbxvxbbbbx
1d1t_A_1751d1t   A182198AAVKTGKVKPGSTCVVFHHHTTS---TT-EEEEEaaaaaalpxxvxbbbbx
1dl5_A_611dl5   A6682LFMEWVGLDKGMRVLEIHHHHHTT--TT-EEEEEaaaaaavpbpvxbbbxb
1dzf_A_1831dzf   A183199PVALYLGLKRGEVVKIIHHHHHHT--TT-EEEEEaaaaaavxbpgxbbxbb
1e3i_A_1791e3i   A186202AAINTAKVTPGSTCAVFHHHTTS---TT-EEEEEaaaaaalpbpvxbbbbb
1ht0_A_1751ht0   A182198SAVKVAKVTPGSTCAVFHHHTTT---TT-EEEEEaaaaaalpbpvxbbbbx
1jg1_A_771jg1   A8298IMLEIANLKPGMNILEVHHHHHHT--TT--EEEEaaaaaalxbpvxbbbbb
1jqb_A_11511jqb   A11571173HGAELADIEMGSSVVVIHHHHHTT--TT--EEEEaaaaaalxbpvxxbbbx
1kol_A_1701kol   A176192HGAVTAGVGPGSTVYVAHHHHHTT--TT-EEEEEaaaaaavxbpvxxbbbx
1kpi_A_531kpi   A6379LALDKLNLEPGMTLLDIHHHHTT---TT-EEEEEaaaaaalxbxgxbxbbx
1m6h_A_1741m6h   A181197AAVNTAKLEPGSVCAVFHHHTTT---TT-EEEEEaaaaaalxxpvxxbbbx
1n8k_A_1751n8k   A182198SAVKVAKVTQGSTCAVFHHHTTT---TT-EEEEEaaaaaalpbxvxbbbbx
1p0f_A_11741p0f   A11811197AAVNTAKVTPGSTCAVFHHHTTT---TT-EEEEEaaaaaavpbpvxbbbbb
1ykf_A_1511ykf   A157173HGAELADIELGATVAVLHHHHHTT--TT--EEEEaaaaaalxbpvxbbbbx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1cdo_A_1761cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE G - 176
1cdo_A_1761cdo   A     ZNZINC ION G - 176
1cdo_A_1761cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 179
1cdo_A_1761cdo   A     ZNZINC ION T - 179
1cdo_A_1761cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE F - 199
1d1t_A_1751d1t   A     ZNZINC ION G - 175
1d1t_A_1751d1t   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE G - 175
1d1t_A_1751d1t   A     ZNZINC ION T - 178
1d1t_A_1751d1t   A     ACTACETATE ION T - 178
1d1t_A_1751d1t   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 178
1d1t_A_1751d1t   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE F - 198
1dl5_A_611dl5   A     SAHS-ADENOSYL-L-HOMOCYSTEINE M - 64
1dl5_A_611dl5   A     SAHS-ADENOSYL-L-HOMOCYSTEINE E - 81
1dl5_A_611dl5   A     SAHS-ADENOSYL-L-HOMOCYSTEINE I - 82
1e3i_A_1791e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE G - 179
1e3i_A_1791e3i   A     ZNZINC ION G - 179
1e3i_A_1791e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE S - 182
1e3i_A_1791e3i   A     CXFCYCLOHEXYLFORMAMIDE S - 182
1e3i_A_1791e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE F - 202
1jg1_A_771jg1   A     SAHS-ADENOSYL-L-HOMOCYSTEINE V - 80
1jg1_A_771jg1   A     SAHS-ADENOSYL-L-HOMOCYSTEINE E - 97
1jg1_A_771jg1   A     SAHS-ADENOSYL-L-HOMOCYSTEINE V - 98
1jqb_A_11511jqb   A     ZNZINC ION M - 1151
1kol_A_1701kol   A     ZNZINC ION I - 170
1kol_A_1701kol   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 170
1kol_A_1701kol   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 173
1kol_A_1701kol   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE H - 176
1kol_A_1701kol   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE Y - 190
1kol_A_1701kol   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE A - 192
1kpi_A_531kpi   A     CO3CARBONATE ION K - 60
1kpi_A_531kpi   A     SAHS-ADENOSYL-L-HOMOCYSTEINE K - 60
1kpi_A_531kpi   A     SAHS-ADENOSYL-L-HOMOCYSTEINE D - 78
1kpi_A_531kpi   A     SAHS-ADENOSYL-L-HOMOCYSTEINE I - 79
1m6h_A_1741m6h   A     ZNZINC ION G - 174
1m6h_A_1741m6h   A     PO4PHOSPHATE ION G - 174
1m6h_A_1741m6h   A     ZNZINC ION T - 177
1m6h_A_1741m6h   A     PO4PHOSPHATE ION T - 185
1n8k_A_1751n8k   A     NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) G - 175
1n8k_A_1751n8k   A     NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) T - 178
1n8k_A_1751n8k   A     PZOPYRAZOLE T - 178
1n8k_A_1751n8k   A     NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) F - 198
1p0f_A_11741p0f   A     ZNZINC ION G - 1174
1p0f_A_11741p0f   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 1174
1p0f_A_11741p0f   A     ZNZINC ION T - 1177
1p0f_A_11741p0f   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE T - 1177
1p0f_A_11741p0f   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE F - 1197
1ykf_A_1511ykf   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE M - 151
1ykf_A_1511ykf   A     ZNZINC ION M - 151
1ykf_A_1511ykf   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE T - 154
1ykf_A_1511ykf   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 173
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1e3i_A_1791e3i   A AC1NAD BINDING SITE FOR CHAIN AS - 182

Clusters included in this Subclass
CLUSTER: HE.6.120
CLUSTER: HE.7.39
CLUSTER: HE.8.3
CLUSTER: HE.9.4