ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 6.5.1

Subclass Accession number: 415
Subclass: 6.5.1

Type: HE alpha-beta
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1.1 (>75 %)  1.1.1 (>75 %)
GO : GO:0005489 (>75 %)
SCOP : 51734 (>50 %)  51735 (>50 %)  51736 (>50 %)  52832 (>75 %)  52833 (>75 %)  52834 (>75 %)

Number of loops: 13

Average sequence ID (%) : 23.0 +/- 19.3
Average RMSD (Å) : 0.646 +/- 0.320

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 45-90

rho (°): 315-360

Consensus Sequence:	pXXhXXhPXh
(φψ)-conformation:	aalpabbwbb

Pattern:	[ailvw]	[ailv]	[cdkqrst]	[adekqr]	[cltvy]	[DEGNQR]	[AFILV]	x	x	[AILMV]	[P]	[aktv]	[FILMTV]	[fikltv]	[AFILV]
Conservation:	-0.525	-0.113	-0.586	-0.398	-0.542	-0.143	0.262	-0.590	-0.790	0.452	3.381	-0.013	-0.079	-0.447	0.131

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a8l_*_182	1a8l	-	184	198	WADQYNVMAVPKIVI	HHHHTT--SS-EEEE	aaaaalxaxbwbbbb
1a8l_*_65	1a8l	-	70	84	LAKRYRIDRAPATTI	HHHHTT--SSSEEEE	aaaaalbabbwbbbx
1aiu_*_63	1aiu	-	65	79	VASECEVKCMPTFQF	HHHHTT--SSSEEEE	aaaaalxabbwbbbb
1f9m_A_78	1f9m	A	80	94	LAKELGIRVVPTFKI	HHHHH--SSSSEEEE	aaaaavbabbwbbbb
1fvk_A_129	1fvk	A	141	155	AAADVQLRGVPAMFV	HHHHTT--SSSEEEE	aaaaalxabbwbbbb
1h75_A_37	1h75	A	42	56	ALRAQGFRQLPVVIA	HHHHTT--SS-EEEE	aaaaavxabbwbbbb
1hyu_A_160	1hyu	A	162	176	EITERNVMGVPAVFV	HHHHTT--SSSEEEE	aaaaavxabbwbbbb
1kte_*_53	1kte	-	60	74	LQQLTGARTVPRVFI	HHHHHS---S-EEEE	aaaaavbaxbwbbbb
1r26_A_61	1r26	A	63	77	IVSKCRVLQLPTFII	HHHHTT--SSSEEEE	aaaaalxabbwbbbb
1r4w_A_162	1r4w	A	174	188	AACKYGAFGLPTTVA	HHHHTT--SS-EEEE	aaaaagpabbwbbbb
1st9_A_129	1st9	A	130	144	VLDAYDVSPLPTTFL	HHHHTT--SS-EEEE	aaaaalxawbwbbbb
1uc7_A_75	1uc7	A	80	94	LLKHLNVLGLPTILF	HHHHHT--SSSEEEE	aaaaavbabbwbbbb
2trx_A_66	2trx	A	66	80	TAPKYGIRGIPTLLL	HHHHTT--SSSEEEE	aaaaavxabbwbbbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1r4w_A_162	1r4w	A	GSHGLUTHATHIONE	F - 181
1r4w_A_162	1r4w	A	GSHGLUTHATHIONE	G - 182
1r4w_A_162	1r4w	A	GSHGLUTHATHIONE	L - 183
1r4w_A_162	1r4w	A	GSHGLUTHATHIONE	P - 184
1st9_A_129	1st9	A	EGLETHYLENE GLYCOL	A - 133
1st9_A_129	1st9	A	EGLETHYLENE GLYCOL	Y - 134
1st9_A_129	1st9	A	EGLETHYLENE GLYCOL	D - 135
1st9_A_129	1st9	A	EGLETHYLENE GLYCOL	F - 143
1st9_A_129	1st9	A	EGLETHYLENE GLYCOL	I - 145
2trx_A_66	2trx	A	MPD2-METHYL-2,4-PENTANEDIOL	A - 67
2trx_A_66	2trx	A	MPD2-METHYL-2,4-PENTANEDIOL	P - 68
2trx_A_66	2trx	A	MPD2-METHYL-2,4-PENTANEDIOL	Y - 70
2trx_A_66	2trx	A	MPD2-METHYL-2,4-PENTANEDIOL	G - 71
2trx_A_66	2trx	A	MPD2-METHYL-2,4-PENTANEDIOL	I - 72
2trx_A_66	2trx	A	MPD2-METHYL-2,4-PENTANEDIOL	R - 73
2trx_A_66	2trx	A	MPD2-METHYL-2,4-PENTANEDIOL	G - 74
2trx_A_66	2trx	A	MPD2-METHYL-2,4-PENTANEDIOL	I - 75
2trx_A_66	2trx	A	MPD2-METHYL-2,4-PENTANEDIOL	T - 77
2trx_A_66	2trx	A	MPD2-METHYL-2,4-PENTANEDIOL	L - 78
2trx_A_66	2trx	A	MPD2-METHYL-2,4-PENTANEDIOL	L - 79

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1fvk_A_129	1fvk	A	CAATHE ACTIVE SITE.	P - 151

Clusters included in this Subclass

CLUSTER: HE.6.13

CLUSTER: HE.7.4

CLUSTER: HE.8.4