ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 2.2.10

Subclass Accession number: 4571
Subclass: 2.2.10

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Number of loops: 11

Average sequence ID (%) : 9.6 +/- 12.5
Average RMSD (Å) : 0.609 +/- 0.234

Consensus geometry

d (Å): 9

delta (°): 90-135

theta (°): 135-180

rho (°): 180-225

Consensus Sequence:	XXXpXX
(φψ)-conformation:	aalpaa

Pattern:	x	x	x	[aglmy]	x	x	[aenqt]	[agknqs]	[adknqr]	x	[cdeqrsty]	x	x	x
Conservation:	-1.367	-0.306	-0.274	0.312	-0.171	1.515	1.752	1.114	-0.065	-0.040	-1.453	-1.037	0.731	-0.711

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ed8_A_325	1ed8	A	326	339	IDKQDHAANPCGQI	HHHHHHTT-HHHHH	aaaaaaalbaaaaa
1eex_G_133	1eex	G	141	154	DDLESRYQAKICAA	HHHHHHH--HHHHH	aaaaaaalxaaaaa
1ew2_A_315	1ew2	A	315	328	IDHGHHESRAYRAL	HHHHHHTT-HHHHH	aaaaaaavbaaaaa
1ia6_A_210	1ia6	A	218	231	TWLYTATNDSTYIT	HHHHHHH--THHHH	aaaaaaavxaaaaa
1k7h_A_313	1k7h	A	314	327	IDHMHHANQIRQSL	HHHHHHTT-HHHHH	aaaaaaavxaaaaa
1mty_D_213	1mty	D	221	234	TEWAAANGDEITPT	HHHHHHTT--HHHH	aaaaaaavxaaaaa
1pqm_A_116	1pqm	A	117	130	SLRMLQQKRWDEAA	HHHHHHHTT-HHHH	aaaaaaavxaaaaa
1qba_*_454	1qba	-	464	477	YKKLHAAGKEQEAN	HHHHHHTT-HHHHH	aaaaaaavxaaaaa
1rxw_A_88	1rxw	A	105	118	WIAALQAGDKDAKK	HHHHHHHT-TTHHH	aaaaaaavxaaaaa
2erl_*_2	2erl	-	3	16	CEQAAIQCVESACE	HHHHHHTT-HHHHH	aaaaaaavbaaaaa
2mhr_*_41	2mhr	-	59	72	EAMMDAAKYSEVVP	HHHHHHTT-TTHHH	aaaaaaalxaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ed8_A_325	1ed8	A	ZNZINC ION	D - 327
1ed8_A_325	1ed8	A	MGMAGNESIUM ION	D - 327
1ed8_A_325	1ed8	A	PO4PHOSPHATE ION	D - 327
1ed8_A_325	1ed8	A	ZNZINC ION	K - 328
1ed8_A_325	1ed8	A	MGMAGNESIUM ION	K - 328
1ed8_A_325	1ed8	A	PO4PHOSPHATE ION	K - 328
1ed8_A_325	1ed8	A	ZNZINC ION	H - 331
1ed8_A_325	1ed8	A	PO4PHOSPHATE ION	H - 331
1ew2_A_315	1ew2	A	ZNZINC ION	D - 316
1ew2_A_315	1ew2	A	MGMAGNESIUM ION	D - 316
1ew2_A_315	1ew2	A	PO4PHOSPHATE ION	D - 316
1ew2_A_315	1ew2	A	ZNZINC ION	H - 317
1ew2_A_315	1ew2	A	MGMAGNESIUM ION	H - 317
1ew2_A_315	1ew2	A	PO4PHOSPHATE ION	H - 317
1ew2_A_315	1ew2	A	ZNZINC ION	H - 320
1ew2_A_315	1ew2	A	PO4PHOSPHATE ION	H - 320
1ia6_A_210	1ia6	A	CACALCIUM ION	G - 210
1ia6_A_210	1ia6	A	CACALCIUM ION	D - 211
1ia6_A_210	1ia6	A	CACALCIUM ION	D - 212
1k7h_A_313	1k7h	A	ZNZINC ION	D - 315
1k7h_A_313	1k7h	A	ZNZINC ION	H - 316
1k7h_A_313	1k7h	A	ZNZINC ION	H - 319
1mty_D_213	1mty	D	FEFE (III) ION	T - 213
1mty_D_213	1mty	D	FEFE (III) ION	I - 239
1mty_D_213	1mty	D	FEFE (III) ION	D - 242
1mty_D_213	1mty	D	FEFE (III) ION	E - 243
1mty_D_213	1mty	D	FEFE (III) ION	H - 246
1pqm_A_116	1pqm	A	PO4PHOSPHATE ION	K - 124
1pqm_A_116	1pqm	A	PO4PHOSPHATE ION	R - 125
1pqm_A_116	1pqm	A	PO4PHOSPHATE ION	W - 126
1pqm_A_116	1pqm	A	PO4PHOSPHATE ION	D - 127
1pqm_A_116	1pqm	A	PO4PHOSPHATE ION	E - 128
1pqm_A_116	1pqm	A	PO4PHOSPHATE ION	A - 129
2mhr_*_41	2mhr	*	AZIAZIDE ION	T - 51
2mhr_*_41	2mhr	*	FEOMU-OXO-DIIRON	H - 54
2mhr_*_41	2mhr	*	AZIAZIDE ION	H - 54
2mhr_*_41	2mhr	*	FEOMU-OXO-DIIRON	F - 55
2mhr_*_41	2mhr	*	AZIAZIDE ION	F - 55
2mhr_*_41	2mhr	*	FEOMU-OXO-DIIRON	E - 58
2mhr_*_41	2mhr	*	AZIAZIDE ION	E - 58
2mhr_*_41	2mhr	*	FEOMU-OXO-DIIRON	E - 59
2mhr_*_41	2mhr	*	FEOMU-OXO-DIIRON	M - 62
2mhr_*_41	2mhr	*	FEOMU-OXO-DIIRON	H - 73
2mhr_*_41	2mhr	*	AZIAZIDE ION	H - 73
2mhr_*_41	2mhr	*	FEOMU-OXO-DIIRON	H - 77
2mhr_*_41	2mhr	*	AZIAZIDE ION	H - 77
2mhr_*_41	2mhr	*	AZIAZIDE ION	F - 80

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1mty_D_213	1mty	D	FE1FE BINDING SITE.	E - 243

Clusters included in this Subclass