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Information on SUBCLASS 4.22.1
Subclass Accession number: 2412
Subclass: 4.22.1 PSSM
Type: HH alpha-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1.3 (>75 %)  1.3.99 (>75 %)  1.3.99.22.3 (>75 %)  2.3 (>75 %)  2.3.1 (>75 %)  2.3.1 (>75 %)  2.3.1.412.3.1.41
GO : GO:0003995 (>75 %)  GO:0004085 (>75 %)  GO:0008415 (>75 %)  GO:0008415 (>75 %)  GO:0016627 (>75 %)  GO:0016746 (>75 %)  GO:0016746 (>75 %)  GO:0016747 (>75 %)  GO:0016747 (>75 %)  
SCOP : 47203 (>75 %)  47204 (>75 %)  47363 (>75 %)  53900 (>75 %)  53900 (>75 %)  53901 (>75 %)  53901 (>75 %)  53902 (>75 %)  53902 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 35.1 +/- 25.0
Average RMSD (Å) : 0.350 +/- 0.129

Consensus geometry
d (Å): 15 delta (°): 0-45 theta (°): 45-90 rho (°): 0-45
Consensus Sequence: XXhEGppp
(φψ)-conformation: aaplepaa
Pattern: [AIV][AEP][KNR][HILY][MY]x[DT][AF][KRT][IP]x[CEQ][IT][FY][E][G][ET][ANS][EQT][IV][MQ]x[ILM]x[IT][AG][GR]x[HL]
Conservation:-0.138-0.7570.112-0.9300.353-0.7140.402-0.493-0.247-0.748-0.891-0.746-0.2392.2172.1802.9460.081-0.268-0.2671.0350.431-0.6950.390-0.722-0.2500.264-0.309-1.409-0.588
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1buc_A_3531buc   A353381VARHMRDAKITQIYEGTNEVQLMVTGGALHHHHHHHHGGGGTTTS-HHHHHHHHHHHHaaaaaaaaaaaaaxvepaaaaaaaaaaaa
1is2_A_4071is2   A407435IPNIYVTFTPACTFEGENTVMMLQTARFLHHHHHHHHGGGGTTTS-HHHHHHHHHHHHaaaaaaaaaaaaaxlMpaaaaaaaaaaaa
1jqi_A_3541jqi   A354382AERYYRDARITEIYEGTSEIQRLVIAGHLHHHHHHHHGGGGTTTS-HHHHHHHHHHHHaaaaaaaaaaaaaxvexaaaaaaaaaaaa
3mdd_A_3623mdd   A362390VEKLMRDAKIYQIYEGTAQIQRIIIAREHHHHHHHHHGGGGTSSS-HHHHHHHHHHHHaaaaaaaaaaaaaxlMpaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1buc_A_3531buc   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 362
1buc_A_3531buc   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 365
1buc_A_3531buc   A     CAAACETOACETYL-COENZYME A I - 365
1buc_A_3531buc   A     FADFLAVIN-ADENINE DINUCLEOTIDE Y - 366
1buc_A_3531buc   A     CAAACETOACETYL-COENZYME A Y - 366
1buc_A_3531buc   A     FADFLAVIN-ADENINE DINUCLEOTIDE E - 367
1buc_A_3531buc   A     CAAACETOACETYL-COENZYME A E - 367
1buc_A_3531buc   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 368
1buc_A_3531buc   A     CAAACETOACETYL-COENZYME A G - 368
1buc_A_3531buc   A     FADFLAVIN-ADENINE DINUCLEOTIDE T - 369
1buc_A_3531buc   A     CAAACETOACETYL-COENZYME A T - 369
1buc_A_3531buc   A     FADFLAVIN-ADENINE DINUCLEOTIDE N - 370
1buc_A_3531buc   A     FADFLAVIN-ADENINE DINUCLEOTIDE E - 371
1buc_A_3531buc   A     FADFLAVIN-ADENINE DINUCLEOTIDE V - 372
1buc_A_3531buc   A     CAAACETOACETYL-COENZYME A V - 372
1buc_A_3531buc   A     FADFLAVIN-ADENINE DINUCLEOTIDE M - 375
1buc_A_3531buc   A     CAAACETOACETYL-COENZYME A M - 375
1buc_A_3531buc   A     CAAACETOACETYL-COENZYME A V - 376
1is2_A_4071is2   A     FADFLAVIN-ADENINE DINUCLEOTIDE P - 416
1is2_A_4071is2   A     FADFLAVIN-ADENINE DINUCLEOTIDE T - 419
1is2_A_4071is2   A     FADFLAVIN-ADENINE DINUCLEOTIDE F - 420
1is2_A_4071is2   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 422
1is2_A_4071is2   A     FADFLAVIN-ADENINE DINUCLEOTIDE E - 423
1is2_A_4071is2   A     FADFLAVIN-ADENINE DINUCLEOTIDE N - 424
1is2_A_4071is2   A     FADFLAVIN-ADENINE DINUCLEOTIDE T - 425
1is2_A_4071is2   A     FADFLAVIN-ADENINE DINUCLEOTIDE V - 426
1is2_A_4071is2   A     FADFLAVIN-ADENINE DINUCLEOTIDE L - 429
1jqi_A_3541jqi   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 363
1jqi_A_3541jqi   A     CAAACETOACETYL-COENZYME A I - 366
1jqi_A_3541jqi   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 366
1jqi_A_3541jqi   A     CAAACETOACETYL-COENZYME A Y - 367
1jqi_A_3541jqi   A     FADFLAVIN-ADENINE DINUCLEOTIDE Y - 367
1jqi_A_3541jqi   A     CAAACETOACETYL-COENZYME A E - 368
1jqi_A_3541jqi   A     FADFLAVIN-ADENINE DINUCLEOTIDE E - 368
1jqi_A_3541jqi   A     CAAACETOACETYL-COENZYME A G - 369
1jqi_A_3541jqi   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 369
1jqi_A_3541jqi   A     CAAACETOACETYL-COENZYME A T - 370
1jqi_A_3541jqi   A     FADFLAVIN-ADENINE DINUCLEOTIDE T - 370
1jqi_A_3541jqi   A     FADFLAVIN-ADENINE DINUCLEOTIDE S - 371
1jqi_A_3541jqi   A     FADFLAVIN-ADENINE DINUCLEOTIDE E - 372
1jqi_A_3541jqi   A     CAAACETOACETYL-COENZYME A I - 373
1jqi_A_3541jqi   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 373
1jqi_A_3541jqi   A     CAAACETOACETYL-COENZYME A Q - 374
1jqi_A_3541jqi   A     CAAACETOACETYL-COENZYME A L - 376
1jqi_A_3541jqi   A     FADFLAVIN-ADENINE DINUCLEOTIDE L - 376
1jqi_A_3541jqi   A     CAAACETOACETYL-COENZYME A V - 377
1jqi_A_3541jqi   A     CAAACETOACETYL-COENZYME A H - 381
1jqi_A_3541jqi   A     CAAACETOACETYL-COENZYME A R - 384
3mdd_A_3623mdd   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 371
3mdd_A_3623mdd   A     FADFLAVIN-ADENINE DINUCLEOTIDE Q - 373
3mdd_A_3623mdd   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 374
3mdd_A_3623mdd   A     FADFLAVIN-ADENINE DINUCLEOTIDE Y - 375
3mdd_A_3623mdd   A     FADFLAVIN-ADENINE DINUCLEOTIDE E - 376
3mdd_A_3623mdd   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 377
3mdd_A_3623mdd   A     FADFLAVIN-ADENINE DINUCLEOTIDE T - 378
3mdd_A_3623mdd   A     FADFLAVIN-ADENINE DINUCLEOTIDE A - 379
3mdd_A_3623mdd   A     FADFLAVIN-ADENINE DINUCLEOTIDE Q - 380
3mdd_A_3623mdd   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 381
3mdd_A_3623mdd   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 384

Clusters included in this Subclass
CLUSTER: HH.8.13