ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 2.2.1

Subclass Accession number: 101
Subclass: 2.2.1
Type: HE alpha-beta
DB: ArchDB-KI

Number of loops: 6

Average sequence ID (%) : 89.7 +/- 2.1
Average RMSD (Å) : 0.27 +/- 0.07

Consensus geometry

d (Å): 7

delta (°): 90-135

theta (°): 135-180

rho (°): 45-90

Consensus Sequence:	EASDGI
(φψ)-conformation:	aapabb

Pattern:	[F]	[D]	[E]	[I]	[L]	[EK]	[AV]	[ST]	[D]	[G]	[IV]	[M]	[V]
Conservation:	1.161	1.161	0.434	-0.294	-0.294	-1.021	-1.748	-1.203	1.161	1.161	-0.657	0.434	-0.294

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a3x_A_250	1a3x	A	250	262	FDEILKVTDGVMV	HHHHHHH-SEEEE	aaaaaaaxabbbx
1a49_A_279	1a49	A	279	291	FDEILEASDGIMV	HHHHHHHSSEEEE	aaaaaaaxabbbx
1aqf_A_279	1aqf	A	279	291	FDEILEASDGIMV	HHHHHHH-SEEEE	aaaaaaababbbx
1pkm_*_279	1pkm	-	279	291	FDEILEASDGIMV	HHHHHHHSSEEEE	aaaaaaaxabbbx
1pkn_*_279	1pkn	-	279	291	FDEILEASDGIMV	HHHHHHH-SEEEE	aaaaaaaxabbbx
1pky_A_230	1pky	A	230	242	FDEILEASDGIMV	HHHHHHHSSEEEE	aaaaaaaxabbbx

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1a3x_A_250	1a3x	A	PGA2-PHOSPHOGLYCOLIC ACID	M - 261
1a3x_A_250	1a3x	A	PGA2-PHOSPHOGLYCOLIC ACID	V - 262
1a3x_A_250	1a3x	A	MNMANGANESE (II) ION	A - 263
1a3x_A_250	1a3x	A	PGA2-PHOSPHOGLYCOLIC ACID	A - 263
1a49_A_279	1a49	A	OXLOXALATE ION	M - 290
1a49_A_279	1a49	A	OXLOXALATE ION	V - 291
1a49_A_279	1a49	A	OXLOXALATE ION	A - 292
1a49_A_279	1a49	A	MGMAGNESIUM ION	A - 292
1aqf_A_279	1aqf	A	PEQL-PHOSPHOLACTATE	M - 290
1aqf_A_279	1aqf	A	PEQL-PHOSPHOLACTATE	V - 291
1aqf_A_279	1aqf	A	PEQL-PHOSPHOLACTATE	A - 292
1aqf_A_279	1aqf	A	MGMAGNESIUM ION	A - 292
1pkn_*_279	1pkn	*	PYRPYRUVIC ACID	M - 290
1pkn_*_279	1pkn	*	PYRPYRUVIC ACID	V - 291
1pkn_*_279	1pkn	*	PYRPYRUVIC ACID	A - 292
1pkn_*_279	1pkn	*	MNMANGANESE (II) ION	A - 292

Clusters included in this Subclass

CLUSTER: HE.2.13