ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 4.12.2

Subclass Accession number: 1266
Subclass: 4.12.2

PSSM

Type: EH beta-alpha
DB: ArchDB40

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Number of loops: 11

Average sequence ID (%) : 11.6 +/- 12.6
Average RMSD (Å) : 0.945 +/- 0.242

Consensus geometry

d (Å): 13

delta (°): 0-45

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	XhXXXcXp
(φψ)-conformation:	bbppapaa

Pattern:	x	[ilptv]	x	[acps]	x	[DEKNS]	x	[denrsy]	[adeqrt]	[ailmtv]	[aekqt]	[aegknqs]	[AILTV]	[acfilvy]	[ekqry]
Conservation:	-0.280	0.862	-0.261	0.678	-1.322	2.484	-1.595	-0.817	-0.112	-0.097	-0.060	-0.603	0.996	-0.196	0.322

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1aye_*_11	1aye	-	14	28	EIVPSNEEQIKNLLQ	EE---SHHHHHHHHH	bbbxabaaaaaaaaa
1ejd_A_364	1ejd	A	364	378	QVMATDLRASASLVL	EE--SSHHHHHHHHH	xbbbaxaaaaaaaaa
1gmu_A_71	1gmu	A	76	90	VVRCDDPFMLAKACY	EEE-S-HHHHHHHHH	bbxbabaaaaaaaaa
1hl2_A_161	1hl2	A	165	179	KQTSGDLYQMEQIRR	EE----HHHHHHHHH	xxxbaxaaaaaaaaa
1hsk_A_48	1hsk	A	52	66	YITPTKNEEVQAVVK	EE--SSHHHHHHHHH	bbbxabaaaaaaaaa
1itz_A_502	1itz	A	503	517	MLRPADGNETAGAYK	EE---SHHHHHHHHH	bxbxabaaaaaaaaa
1k66_A_117	1k66	A	119	133	IVKPLEIDRLTETVQ	EE--SSHHHHHHHHH	bxxxaxaaaaaaaaa
1k68_A_118	1k68	A	120	134	ITKSANLSQLFQIVK	EE--SSHHHHHHHHH	bxxxaxaaaaaaaaa
1luc_A_170	1luc	A	171	185	YVVAESASTTEWAAE	EE---SHHHHHHHHH	bbxxabaaaaaaaaa
1ni4_B_143	1ni4	B	144	158	VVSPWNSEDAKGLIK	EE---SHHHHHHHHH	bbbxaxaaaaaaaaa
1v4v_A_232	1v4v	A	235	249	YPVHLNPVVREAVFP	EE--S-HHHHHHHHH	bxxpapaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ejd_A_364	1ejd	A	PO4PHOSPHATE ION	T - 368
1ejd_A_364	1ejd	A	PO4PHOSPHATE ION	L - 370
1hl2_A_161	1hl2	A	3PY3-HYDROXYPYRUVIC ACID	K - 165
1hl2_A_161	1hl2	A	3PY3-HYDROXYPYRUVIC ACID	T - 167
1k68_A_118	1k68	A	PHDASPARTYL PHOSPHATE	K - 122
1k68_A_118	1k68	A	MGMAGNESIUM ION	K - 122
1luc_A_170	1luc	A	EDO1,2-ETHANEDIOL	E - 175
1luc_A_170	1luc	A	EDO1,2-ETHANEDIOL	S - 176
1luc_A_170	1luc	A	EDO1,2-ETHANEDIOL	S - 178
1luc_A_170	1luc	A	EDO1,2-ETHANEDIOL	T - 179
1luc_A_170	1luc	A	EDO1,2-ETHANEDIOL	W - 182
1ni4_B_143	1ni4	B	MSESELENOMETHIONINE	S - 146
1ni4_B_143	1ni4	B	MSESELENOMETHIONINE	P - 147
1ni4_B_143	1ni4	B	MSESELENOMETHIONINE	W - 148
1ni4_B_143	1ni4	B	MSESELENOMETHIONINE	N - 149
1ni4_B_143	1ni4	B	MSESELENOMETHIONINE	I - 157
1ni4_B_143	1ni4	B	MSESELENOMETHIONINE	K - 158
1ni4_B_143	1ni4	B	MSESELENOMETHIONINE	I - 161
1v4v_A_232	1v4v	A	MSESELENOMETHIONINE	Y - 235
1v4v_A_232	1v4v	A	MSESELENOMETHIONINE	P - 236
1v4v_A_232	1v4v	A	MSESELENOMETHIONINE	V - 237
1v4v_A_232	1v4v	A	MSESELENOMETHIONINE	H - 238
1v4v_A_232	1v4v	A	MSESELENOMETHIONINE	V - 243
1v4v_A_232	1v4v	A	MSESELENOMETHIONINE	V - 247
1v4v_A_232	1v4v	A	MSESELENOMETHIONINE	L - 251

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1hl2_A_161	1hl2	A	CATCATALYTIC LYSINE FORMING SCHIFF BASE	K - 165
1hl2_A_161	1hl2	A	AC13PY BINDING SITE FOR CHAIN A	T - 167

Clusters included in this Subclass

CLUSTER: EH.3.135

CLUSTER: EH.4.65

CLUSTER: EH.5.111