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Information on SUBCLASS 3.4.2
Subclass Accession number: 127
Subclass: 3.4.2
Type: HE alpha-beta
DB: ArchDB-KI
 Number of loops: 3

Average sequence ID (%) : 24.2 +/- 2.4
Average RMSD (Å) : 0.60 +/- 0.23

Consensus geometry
d (Å): 7 delta (°): 45-90 theta (°): 135-180 rho (°): 90-135
Consensus Sequence: XXXPpXX
(φψ)-conformation: aabaabb
Pattern: x[ST]xxxxx[ST][CLV]xx[EL]x[P][DK][CS]x[V]x[FL][IL][LV]
Conservation:-0.3860.426-0.640-1.513-0.5970.069-0.4560.566-0.245-0.316-1.020-0.780-1.0203.1350.2151.131-0.5971.234-0.6680.5010.6310.330
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1bdg_*_2091bdg   -209230DTVGTLASCALEDPKCAVGLIVHHHHHHHHHHTT-TTEEEEEEEaaaaaaaaaaaabaaxabbxbb
1cza_N_4231cza   N423444YSRRFHKTLRRLVPDSDVRFLLHHHHHHHHHHHH-TTEEEEEEEaaaaaaaaaaaabaabbbbbbx
1cza_N_8711cza   N871892FSRIMHQTVKELSPKCNVSFLLHHHHHHHHHHHHSTTEEEEEEEaaaaaaaaaaaabaabbbbbbx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1bdg_*_2091bdg   *     GLCGLUCOSE D - 209
1bdg_*_2091bdg   *     GLCGLUCOSE T - 210
1bdg_*_2091bdg   *     GLCGLUCOSE I - 229
1cza_N_4231cza   N     ADPADENOSINE-5'-DIPHOSPHATE R - 425
1cza_N_4231cza   N     ADPADENOSINE-5'-DIPHOSPHATE R - 426
1cza_N_4231cza   N     ADPADENOSINE-5'-DIPHOSPHATE K - 429
Bibliographic annotations
LoopPDBChainAnnotationResidue
1cza_N_4231cza   RefA.E.ALESHIN,C.KIRBY,X.LIU,G.P.BOURENKOV,H.D.BARTUNIK,H.J.FROMM,R.B.HONZATKO. CRYSTAL STRUCTURES OF MUTANT MONOMERIC HEXOKINASE I REVEAL MULTIPLE ADP BINDING SITES AND CONFORMATIONAL CHANGES RELEVANT TO ALLOSTERIC REGULATION  J.MOL.BIOL. v.296;1001,2000NREGULATORY ADP BINDING RESIDUER - 425
1cza_N_4231cza   RefA.E.ALESHIN,C.KIRBY,X.LIU,G.P.BOURENKOV,H.D.BARTUNIK,H.J.FROMM,R.B.HONZATKO. CRYSTAL STRUCTURES OF MUTANT MONOMERIC HEXOKINASE I REVEAL MULTIPLE ADP BINDING SITES AND CONFORMATIONAL CHANGES RELEVANT TO ALLOSTERIC REGULATION  J.MOL.BIOL. v.296;1001,2000NREGULATORY ADP BINDING RESIDUER - 426

Clusters included in this Subclass
CLUSTER: HE.4.19