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Information on SUBCLASS 0.1.2
Subclass Accession number: 14
Subclass: 0.1.2
Type: EH beta-alpha
DB: ArchDB-KI
 Number of loops: 6

Average sequence ID (%) : 67.4 +/- 16.0
Average RMSD (Å) : 0.36 +/- 0.25

Consensus geometry
d (Å): 3 delta (°): 0-45 theta (°): 45-90 rho (°): 225-270
Consensus Sequence: VARG
(φψ)-conformation: bbaa
Pattern: [CIV][IM][MV][AL][RS][G][DE][LT][AG]
Conservation:-0.4770.004-0.035-0.909-0.7102.3100.721-0.749-0.154
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a3x_A_2591a3x   A260268VMVARGDLGEEEEHHHHHbbxxaaaaa
1a49_A_2881a49   A289297IMVARGDLGEEEEHHHHHbbxxaaaaa
1aqf_A_2881aqf   A289297IMVARGDLGEEEEHHHHHbbxxaaaaa
1pkm_*_2881pkm   -289297IMVARGDLGEEEEHHHHHbbxxaaaaa
1pkm_*_3571pkm   -357365CIMLSGETAEEEESHHHHbbbbaaaaa
1pkn_*_2881pkn   -289297IMVARGDLGEEEEHHHHHbbxxaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a3x_A_2591a3x   A     PGA2-PHOSPHOGLYCOLIC ACID M - 261
1a3x_A_2591a3x   A     PGA2-PHOSPHOGLYCOLIC ACID V - 262
1a3x_A_2591a3x   A     MNMANGANESE (II) ION A - 263
1a3x_A_2591a3x   A     PGA2-PHOSPHOGLYCOLIC ACID A - 263
1a3x_A_2591a3x   A     PGA2-PHOSPHOGLYCOLIC ACID R - 264
1a3x_A_2591a3x   A     MNMANGANESE (II) ION G - 265
1a3x_A_2591a3x   A     PGA2-PHOSPHOGLYCOLIC ACID G - 265
1a3x_A_2591a3x   A     MNMANGANESE (II) ION D - 266
1a3x_A_2591a3x   A     PGA2-PHOSPHOGLYCOLIC ACID D - 266
1a3x_A_2591a3x   A     MNMANGANESE (II) ION L - 267
1a3x_A_2591a3x   A     PGA2-PHOSPHOGLYCOLIC ACID L - 267
1a49_A_2881a49   A     OXLOXALATE ION M - 290
1a49_A_2881a49   A     OXLOXALATE ION V - 291
1a49_A_2881a49   A     OXLOXALATE ION A - 292
1a49_A_2881a49   A     MGMAGNESIUM ION A - 292
1a49_A_2881a49   A     OXLOXALATE ION R - 293
1a49_A_2881a49   A     OXLOXALATE ION G - 294
1a49_A_2881a49   A     MGMAGNESIUM ION G - 294
1a49_A_2881a49   A     OXLOXALATE ION D - 295
1a49_A_2881a49   A     MGMAGNESIUM ION D - 295
1a49_A_2881a49   A     ATPADENOSINE-5'-TRIPHOSPHATE D - 295
1a49_A_2881a49   A     OXLOXALATE ION L - 296
1a49_A_2881a49   A     MGMAGNESIUM ION L - 296
1aqf_A_2881aqf   A     PEQL-PHOSPHOLACTATE M - 290
1aqf_A_2881aqf   A     PEQL-PHOSPHOLACTATE V - 291
1aqf_A_2881aqf   A     PEQL-PHOSPHOLACTATE A - 292
1aqf_A_2881aqf   A     MGMAGNESIUM ION A - 292
1aqf_A_2881aqf   A     PEQL-PHOSPHOLACTATE R - 293
1aqf_A_2881aqf   A     PEQL-PHOSPHOLACTATE G - 294
1aqf_A_2881aqf   A     MGMAGNESIUM ION G - 294
1aqf_A_2881aqf   A     PEQL-PHOSPHOLACTATE D - 295
1aqf_A_2881aqf   A     MGMAGNESIUM ION D - 295
1aqf_A_2881aqf   A     PEQL-PHOSPHOLACTATE L - 296
1pkn_*_2881pkn   *     PYRPYRUVIC ACID M - 290
1pkn_*_2881pkn   *     PYRPYRUVIC ACID V - 291
1pkn_*_2881pkn   *     PYRPYRUVIC ACID A - 292
1pkn_*_2881pkn   *     MNMANGANESE (II) ION A - 292
1pkn_*_2881pkn   *     PYRPYRUVIC ACID R - 293
1pkn_*_2881pkn   *     PYRPYRUVIC ACID G - 294
1pkn_*_2881pkn   *     MNMANGANESE (II) ION G - 294
1pkn_*_2881pkn   *     PYRPYRUVIC ACID D - 295
1pkn_*_2881pkn   *     MNMANGANESE (II) ION D - 295
1pkn_*_2881pkn   *     PYRPYRUVIC ACID L - 296
Bibliographic annotations
LoopPDBChainAnnotationResidue
1a49_A_2881a49   RefT.M.LARSEN,M.M.BENNING,I.RAYMENT,G.H.REED. STRUCTURE OF THE BIS(MG2+)-ATP-OXALATE COMPLEX OF THE RABBIT MUSCLE PYRUVATE KINASE AT 2.1 A RESOLUTION: ATP BINDING OVER A BARREL  BIOCHEMISTRY v.37;6247,1998AMg ION BINDING RESIDUE (ATP)D - 295
1a49_A_2881a49   RefT.M.LARSEN,M.M.BENNING,I.RAYMENT,G.H.REED. STRUCTURE OF THE BIS(MG2+)-ATP-OXALATE COMPLEX OF THE RABBIT MUSCLE PYRUVATE KINASE AT 2.1 A RESOLUTION: ATP BINDING OVER A BARREL  BIOCHEMISTRY v.37;6247,1998AMg ION BINDING RESIDUE (ATP)D - 295
1a49_A_2881a49   RefT.M.LARSEN,M.M.BENNING,I.RAYMENT,G.H.REED. STRUCTURE OF THE BIS(MG2+)-ATP-OXALATE COMPLEX OF THE RABBIT MUSCLE PYRUVATE KINASE AT 2.1 A RESOLUTION: ATP BINDING OVER A BARREL  BIOCHEMISTRY v.37;6247,1998AP-ATP BINDING RESIDUED - 295
1aqf_A_2881aqf   RefT.M.LARSEN,M.M.BENNING,G.E.WESENBERG,I.RAYMENT,G.H.REED. LIGAND-INDUCED DOMAIN MOVEMENT IN PYRUVATE KINASE: STRUCTURE OF THE ENZYME FROM RABBIT MUSCLE WITH MG2+, K+, AND L-PHOSPHOLACTATE AT 2.7 A RESOLUTION  ARCH.BIOCHEM.BIOPHYS. v.345;199,1997AMg ION BINDING RESIDUED - 295
1aqf_A_2881aqf   RefT.M.LARSEN,M.M.BENNING,G.E.WESENBERG,I.RAYMENT,G.H.REED. LIGAND-INDUCED DOMAIN MOVEMENT IN PYRUVATE KINASE: STRUCTURE OF THE ENZYME FROM RABBIT MUSCLE WITH MG2+, K+, AND L-PHOSPHOLACTATE AT 2.7 A RESOLUTION  ARCH.BIOCHEM.BIOPHYS. v.345;199,1997AMg ION BINDING RESIDUED - 295

Clusters included in this Subclass
CLUSTER: EH.0.3