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Information on SUBCLASS 6.2.1
Subclass Accession number: 1458
Subclass: 6.2.1 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
SCOP : 56511 (>75 %)  56512 (>75 %)  56513 (>75 %)  
 Number of loops: 23

Average sequence ID (%) : 11.9 +/- 15.2
Average RMSD (Å) : 0.913 +/- 0.265

Consensus geometry
d (Å): 13 delta (°): 45-90 theta (°): 135-180 rho (°): 225-270
Consensus Sequence: XXhXXpXXXp
(φψ)-conformation: bbppaabpaa
Pattern: xxxx[AGLPVWY][adenpst][dehkpq][adegnqrst]x[dhnprst]x[ADEKS][adegknqrst][afgilmtv][adgknrt]
Conservation:-1.000-0.926-0.477-1.514-0.370-0.2591.0620.339-0.1450.058-1.0582.4810.6070.594-0.392
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1fbl_*_1131fbl   -117131RIENYTPDLSREDVDEE----TTS-HHHHHbxabbxaabpaaaaa
1goi_A_601goi   A6072..CAWDPATNDAKAR..EE--TT--HHHHH..xbxpaaxxaaaaa
1gve_A_1031gve   A107121YLHFPDHGTPIEETLEE-S--TTS-HHHHHbxabxbaabpaaaaa
1hnj_A_411hnj   A4155ERHIAAPNETVSTMGEEEE--TT--HHHHHbbxbxxaabbaaaaa
1hzp_A_411hzp   A4155TRRFAADDESAASMAEEEE--TT--HHHHHbbbbxxaabbaaaaa
1i7q_A_4771i7q   A482496AGAGVVQDSIPEREAEE--B-TT--HHHHHbbbxbbaaxbaaaaa
1j93_A_2691j93   A269282.VVSLDWTVDMADGR.EEE--TTS-HHHHH.bbxxxaabxaaaaa
1jk3_A_1131jk3   A117131RINNYTPDMNREDVDEE-S--TTS-HHHHHbxabbxaabxaaaaa
1jkx_A_1481jkx   A152166AKVPVFAGDSEDDITEEEE--TT--HHHHHbbbxbbaapxaaaaa
1jqb_A_11341jqb   A11341146..AILPKDMPLENAV..EE--TTS-HHHHH..bxxpaaxpaaaaa
1k0g_A_3451k0g   A345358.TAQLPEQLHASDLL.EEE--TT--HHHHH.bbbxwaabbaaaaa
1l6j_A_1201l6j   A124138WIQNYSEDLPRAVIDEE----TTS-HHHHHbxabbxaabxaaaaa
1lou_A_21lou   A620VNIVLNPNLDQSQLAEEEEE-TT--HHHHHbbbbbpaaxxaaaaa
1mdb_A_1011mdb   A101115LPVFALPSHRSSEITEEEE--TT--HHHHHbxbxxbaaxbaaaaa
1ogw_A_121ogw   A1327ITLEVEPSDTIENVKEEEE--TTSBHHHHHbbbbbbaaxxaaaaa
1pyf_A_1211pyf   A123137YIHFPDEHTPKDEAVEE-S--SSS-HHHHHbxabxxaaxpaaaaa
1pz1_A_1211pz1   A123137QVHWPDPLVPIEETAEE-S--TTS-HHHHHbxabxbaabpaaaaa
1qmh_A_2471qmh   A250264FFVVGEKRVSAEVVAEEEE--TT--HHHHHbbbxxxaabxaaaaa
1qor_A_1061qor   A106119.AAILPAAISFEQAA.EEE--TTS-HHHHH.bbxxxaabxaaaaa
1r29_A_711r29   A7184.VINLDPEINPEGFN.EEE--TTS-HHHHH.bbxxpaaxxaaaaa
1r3s_A_2791r3s   A279292.VVGLDWTVAPKKAR.EEE--TTS-HHHHH.bbxbxaaxxaaaaa
1slm_*_961slm   -100114RIVNYTPDLPKDAVDEE----TTS-HHHHHbxabbxaabxaaaaa
1ub7_A_401ub7   A4054ERRVAAEDEYTSDLAEEEE--TT--HHHHHbbxbxpaabbaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1fbl_*_1131fbl   *     CACALCIUM ION T - 122
1fbl_*_1131fbl   *     CACALCIUM ION P - 123
1fbl_*_1131fbl   *     CACALCIUM ION D - 124
1gve_A_1031gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE H - 109
1gve_A_1031gve   A     CITCITRIC ACID H - 109
1gve_A_1031gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE F - 110
1gve_A_1031gve   A     CITCITRIC ACID F - 110
1gve_A_1031gve   A     GOLGLYCEROL D - 112
1gve_A_1031gve   A     GOLGLYCEROL H - 113
1gve_A_1031gve   A     GOLGLYCEROL G - 114
1gve_A_1031gve   A     GOLGLYCEROL T - 115
1gve_A_1031gve   A     GOLGLYCEROL I - 117
1hzp_A_411hzp   A     GOLGLYCEROL R - 43
1hzp_A_411hzp   A     GOLGLYCEROL D - 47
1hzp_A_411hzp   A     GOLGLYCEROL D - 48
1hzp_A_411hzp   A     GOLGLYCEROL E - 49
1hzp_A_411hzp   A     GOLGLYCEROL S - 50
1hzp_A_411hzp   A     GOLGLYCEROL S - 53
1hzp_A_411hzp   A     GOLGLYCEROL R - 61
1i7q_A_4771i7q   A     PYRPYRUVIC ACID Q - 481
1i7q_A_4771i7q   A     PYRPYRUVIC ACID A - 482
1i7q_A_4771i7q   A     BEZBENZOIC ACID G - 483
1i7q_A_4771i7q   A     PYRPYRUVIC ACID G - 483
1i7q_A_4771i7q   A     MGMAGNESIUM ION A - 484
1i7q_A_4771i7q   A     BEZBENZOIC ACID A - 484
1i7q_A_4771i7q   A     PYRPYRUVIC ACID A - 484
1i7q_A_4771i7q   A     MGMAGNESIUM ION G - 485
1i7q_A_4771i7q   A     BEZBENZOIC ACID G - 485
1i7q_A_4771i7q   A     PYRPYRUVIC ACID G - 485
1i7q_A_4771i7q   A     MGMAGNESIUM ION E - 495
1i7q_A_4771i7q   A     BEZBENZOIC ACID E - 495
1i7q_A_4771i7q   A     MGMAGNESIUM ION E - 498
1i7q_A_4771i7q   A     BEZBENZOIC ACID E - 498
1i7q_A_4771i7q   A     MGMAGNESIUM ION K - 502
1i7q_A_4771i7q   A     BEZBENZOIC ACID K - 502
1i7q_A_4771i7q   A     PYRPYRUVIC ACID K - 502
1jkx_A_1481jkx   A     138N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY -QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE T - 166
1jkx_A_1481jkx   A     138N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY -QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE V - 169
1jkx_A_1481jkx   A     138N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY -QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE Q - 170
1jkx_A_1481jkx   A     138N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY -QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE E - 173
1jkx_A_1481jkx   A     138N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY -QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE H - 174
1l6j_A_1201l6j   A     CACALCIUM ION S - 129
1l6j_A_1201l6j   A     CACALCIUM ION D - 131
1ogw_A_121ogw   A     LEF(4S)-5-FLUORO-L-LEUCINE L - 15
1ogw_A_121ogw   A     LEF(4S)-5-FLUORO-L-LEUCINE I - 23
1ogw_A_121ogw   A     LEF(4S)-5-FLUORO-L-LEUCINE V - 26
1ogw_A_121ogw   A     LEF(4S)-5-FLUORO-L-LEUCINE K - 27
1ogw_A_121ogw   A     LEF(4S)-5-FLUORO-L-LEUCINE I - 30
1pyf_A_1211pyf   A     MSESELENOMETHIONINE L - 121
1pyf_A_1211pyf   A     MSESELENOMETHIONINE Y - 123
1pyf_A_1211pyf   A     MSESELENOMETHIONINE N - 138
1pyf_A_1211pyf   A     MSESELENOMETHIONINE A - 139
1pyf_A_1211pyf   A     MSESELENOMETHIONINE L - 140
1pyf_A_1211pyf   A     MSESELENOMETHIONINE N - 141
1pz1_A_1211pz1   A     MSESELENOMETHIONINE Y - 122
1pz1_A_1211pz1   A     MSESELENOMETHIONINE Q - 123
1pz1_A_1211pz1   A     MSESELENOMETHIONINE V - 124
1pz1_A_1211pz1   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE H - 125
1pz1_A_1211pz1   A     MSESELENOMETHIONINE W - 126
1pz1_A_1211pz1   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE W - 126
1pz1_A_1211pz1   A     MSESELENOMETHIONINE E - 135
1pz1_A_1211pz1   A     MSESELENOMETHIONINE T - 136
1pz1_A_1211pz1   A     MSESELENOMETHIONINE A - 137
1pz1_A_1211pz1   A     MSESELENOMETHIONINE E - 138
1qor_A_1061qor   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 123
1qor_A_1061qor   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE K - 124
1qor_A_1061qor   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE T - 127
1qor_A_1061qor   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Y - 130
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gve_A_1031gve   A BC5CIT BINDING SITE FOR CHAIN AH - 109
1gve_A_1031gve   A AC7GOL BINDING SITE FOR CHAIN AH - 113

Clusters included in this Subclass
CLUSTER: EH.5.259
CLUSTER: EH.5.58
CLUSTER: EH.6.138
CLUSTER: EH.6.53
CLUSTER: EH.7.1
CLUSTER: EH.8.5