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Information on SUBCLASS 13.2.1
Subclass Accession number: 1585
Subclass: 13.2.1 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1.18 (>75 %)  1.18.1 (>75 %)  1.18.1.23.4 (>75 %)  3.4 (>75 %)  3.4.23 (>75 %)  3.4.23 (>75 %)  
GO : GO:0004175 (>50 %)  GO:0004175 (>75 %)  GO:0004190 (>50 %)  GO:0004190 (>75 %)  GO:0004324 (>75 %)  GO:0005489 (>75 %)  GO:0008233 (>50 %)  GO:0008233 (>75 %)  GO:0008937 (>75 %)  GO:0016730 (>75 %)  GO:0016731 (>75 %)  
SCOP : 50629 (>75 %)  50629 (>75 %)  50630 (>75 %)  50630 (>75 %)  50646 (>75 %)  50646 (>75 %)  52342 (>75 %)  52343 (>75 %)  52344 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 40.9 +/- 21.9
Average RMSD (Å) : 0.400 +/- 0.141

Consensus geometry
d (Å): 7 delta (°): 45-90 theta (°): 45-90 rho (°): 90-135
Consensus Sequence: hGhGhXpXXhGpVXPhh
(φψ)-conformation: bpappaaappllpppaa
Pattern: [G][IV][LV][G][LM][G][FWY]x[DET]x[AS][IV][DG][KRS][AV][DTV][P][IPV][FVW]x[EKN][AILM]
Conservation:1.6410.363-0.1041.6410.1891.6410.527-1.337-0.465-1.034-0.1040.3380.058-0.474-0.300-1.1092.162-0.788-0.483-1.187-0.370-0.805
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1dpj_A_1191dpj   A119140GILGLGYDTISVDKVVPPFYNAEEEE-S-GGG-GGG---HHHHHbbbxaxxaaaxxvlxxxaaaaa
1hrn_A_1191hrn   A119140GVVGMGFIEQAIGRVTPIFDNIEEEE-S-GGG-GGG---HHHHHbbbxaxxaaaxxvUpxxaaaaa
1lf2_A_1221lf2   A122143GILGLGWKDLSIGSVDPIVVELEEEE-S-GGGSTT----HHHHHbbbxaxxaaaxxvlxxwaaaaa
1qdm_A_1241qdm   A124145GILGLGFKEISVGKAVPVWYKMEEEE-S-GGG-GGG---HHHHHbbbxaxxaaaxxvlxxpaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1dpj_A_1191dpj   A     MANALPHA-D-MANNOSE D - 126
1dpj_A_1191dpj   A     NAGN-ACETYL-D-GLUCOSAMINE V - 130
1dpj_A_1191dpj   A     NAGN-ACETYL-D-GLUCOSAMINE D - 131
1dpj_A_1191dpj   A     MANALPHA-D-MANNOSE K - 132
1dpj_A_1191dpj   A     NAGN-ACETYL-D-GLUCOSAMINE K - 132
1dpj_A_1191dpj   A     MANALPHA-D-MANNOSE V - 133
1dpj_A_1191dpj   A     NAGN-ACETYL-D-GLUCOSAMINE V - 133
1dpj_A_1191dpj   A     MANALPHA-D-MANNOSE V - 134
1dpj_A_1191dpj   A     NAGN-ACETYL-D-GLUCOSAMINE V - 134
1dpj_A_1191dpj   A     MANALPHA-D-MANNOSE P - 135
1dpj_A_1191dpj   A     MANALPHA-D-MANNOSE Y - 138
1dpj_A_1191dpj   A     MANALPHA-D-MANNOSE N - 139
1dpj_A_1191dpj   A     MANALPHA-D-MANNOSE I - 141
1dpj_A_1191dpj   A     MANALPHA-D-MANNOSE Q - 142
1hrn_A_1191hrn   A     CHA1-HYDROXY-2-AMINO-3-CYCLOHEXYLPROPANE G - 119
1hrn_A_1191hrn   A     CHA1-HYDROXY-2-AMINO-3-CYCLOHEXYLPROPANE V - 120
1hrn_A_1191hrn   A     IP31-HYDROXY-3-METHYLBUTANE Q - 128
1hrn_A_1191hrn   A     NAGN-ACETYL-D-GLUCOSAMINE G - 131
1lf2_A_1221lf2   A     R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE I - 123
1lf2_A_1221lf2   A     R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE L - 131
1lf2_A_1221lf2   A     R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE S - 132
1lf2_A_1221lf2   A     R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE I - 133

Clusters included in this Subclass
CLUSTER: EH.12.5