ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 5.2.1

Subclass Accession number: 178
Subclass: 5.2.1
Type: HH alpha-alpha
DB: ArchDB-KI

Number of loops: 6

Average sequence ID (%) : 28.4 +/- 3.2
Average RMSD (Å) : 0.49 +/- 0.13

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 90-135

rho (°): 180-225

Consensus Sequence:	XhXpXpXpX
(φψ)-conformation:	aalbppbaa

Pattern:	[IP]	[EN]	[ITV]	x	{AL}	x	{EKRS}	x	{QY}	x	{KRT}	x	x	[D]	[CLMW]	x	x	[ILV]	[G]	{CVY}	[ILV]	[AFGIL]	[AMY]	x	[FLM]	{AFL}	x
Conservation:	0.400	0.767	0.214	-0.510	-0.806	-0.513	-0.770	-0.566	-0.116	-0.123	-0.690	-0.953	-0.571	2.647	-0.306	1.584	0.511	0.619	2.647	-0.671	0.613	-0.949	-0.157	-0.793	0.308	-0.873	-0.941

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a06_*_187	1a06	-	187	213	PEVLAQKPYSKAVDCWSIGVIAYILLC	HHHHTT----THHHHHHHHHHHHHHHH	aaaaalbpxbaaaaaaaaaaaaaaaaN
1blx_A_188	1blx	A	188	214	PEVLLQSSYATPVDLWSVGCIFAEMFR	HHHHTT----THHHHHHHHHHHHHHHH	aaaaalxxbba-aaaaaaaaaaaaaaa
1cdk_A_207	1cdk	A	207	233	PEIILSKGYNKAVDWWALGVLIYEMAA	HHHHTT--B-TTHHHHHHHHHHHHHHH	aaaaavbxbbaaaaaaaaaaaaaaaaa
1cki_A_187	1cki	A	187	213	INTHLGIEQSRRDDLESLGYVLMYFNL	HHHHTTB---HHHHHHHHHHHHHHHHH	aaaaavbxxbaaaaaaaaaaaaaaaaa
1kob_A_219	1kob	A	219	245	PEIVDREPVGFYTDMWAIGVLGYVLLS	HHHHTT--B-HHHHHHHHHHHHHHHHH	aaaaalbxbbaaaaaaaaaaaaaaaaN
2csn_*_187	2csn	-	187	213	INTHLGREQSRRDDLEALGHVFMYFLR	HHHHTT----HHHHHHHHHHHHHHHHH	aaaaavxxxbaaaaaaaaaaaaaaaaa

Bibliographic annotations

Loop	PDB	Chain	Annotation	Residue
1cdk_A_207	1cdk RefD.BOSSEMEYER,R.A.ENGH,V.KINZEL,H.PONSTINGL,R.HUBER. PHOSPHOTRANSFERASE AND SUBSTRATE BINDING MECHANISM OF THE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT FROM PORCINE HEART AS DEDUCED FROM THE 2.0 ANGSTROMS STRUCTURE OF THE COMPLEX WITH MN==2+== ADENYLYL IMIDODIPHOSPHATE AND INHIBITOR PEPTIDE PKI(5-24) EMBO J. v.12;849,1993	A	PKI PEPTIDE BINDING RESIDUE	E - 230

Clusters included in this Subclass