ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 9.1.4

Subclass Accession number: 189
Subclass: 9.1.4
Type: HH alpha-alpha
DB: ArchDB-KI

Number of loops: 3

Average sequence ID (%) : 63.2 +/- 6.8
Average RMSD (Å) : 0.23 +/- 0.07

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 135-180

rho (°): 180-225

Consensus Sequence:	CWpXXPppRPTFp
(φψ)-conformation:	aapapaaapppaa

Pattern:	[EN]	[E]	[L]	[Y]	x	[IM]	[M]	x	[DR]	[C]	[W]	[HK]	x	x	[P]	[ES]	[EQ]	[R]	[P]	[T]	[F]	[EK]	[QY]	[IL]	x	[ES]	x	[L]	[D]
Conservation:	-0.495	0.403	0.003	1.201	-0.894	-0.495	0.403	-0.795	-0.894	1.999	2.797	-0.495	-0.994	-1.294	1.201	-0.695	-0.196	0.403	1.201	0.403	0.802	-0.396	-0.595	-0.396	-1.094	-0.695	-1.194	0.003	0.802

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ad5_A_489	1ad5	A	489	517	EELYNIMMRCWKNRPEERPTFEYIQSVLD	HHHHHHHHHHT-SSGGGS--HHHHHHHHH	aaaaaaaaaaaxaxaaaxxxaaaaaaaaa
1fgk_A_727	1fgk	A	727	755	NELYMMMRDCWHAVPSQRPTFKQLVEDLD	HHHHHHHHHHT-SSGGGS--HHHHHHHHH	aaaaaaaaaaaxaxaaaxxxaaaaaaaaa
2fgi_A_727	2fgi	A	727	755	NELYMMMRDCWHAVPSQRPTFKQLVEDLD	HHHHHHHHHHT-SSGGGS--HHHHHHHHH	aaaaaaaaaaaxaxaaaxxxaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Bibliographic annotations

Loop	PDB	Chain	Annotation	Residue
1fgk_A_727	1fgk RefM.MOHAMMADI, J.SCHLESSINGER, S.R.HUBBARD. STRUCTURE OF THE FGF RECEPTOR TYROSINE KINASE DOMAIN REVEALS A NOVEL AUTOINHIBITORY MECHANISM CELL v.86;577,1996	A	PHOSPHORYLATION SITE	Y - 730

Clusters included in this Subclass